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Insulin Degludec

Uses of Insulin Degludec

  • Insulin Degludec is mainly used to manage high blood sugar levels in people with type 1 and type 2 diabetes. It falls under the class of long-acting insulin.

  • It is also used in combination with other diabetes medicines when required.

Side effects of Insulin Degludec

  • Hypoglycemia

  • Injection site reactions

  • Weight gain

  • Upper respiratory tract infections

  • Back pain

How Insulin Degludec works

  • Insulin Degludec is a long-acting basal insulin analogue.

  • It works by mimicking natural insulin, helping glucose enter cells for energy while lowering the amount of glucose in the bloodstream. Its ultra-long duration of action provides steady, prolonged blood sugar control, usually requiring once-daily dosing.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Insulin Degludec is available as a clear, colourless solution for subcutaneous injection in various concentrations.

  • The medicine is also supplied for single-patient-use in injectable pens for administering under the skin.

Age and Dose Restrictions

  • Insulin Degludec is indicated for use in adults as well as children who are 1 year of age and older.

  • It is used to manage high blood sugar levels in individuals with type 1 and type 2 diabetes mellitus.

Contraindications

  • Insulin Degludec is contraindicated in patients who have a known hypersensitivity to this medicine or any of its components.

Other Medications to Avoid

  • Insulin Degludec can interact with Thiazolidinediones (such as rosiglitazone, pioglitazone), other antidiabetic agents (like metformin, glyburide), ACE inhibitors (including lisinopril, enalapril), angiotensin II receptor blocking agents (such as losartan, valsartan), cholesterol-lowering medications (like fenofibrate, gemfibrozil), monoamine oxidase inhibitors (including selegiline, phenelzine), salicylates (such as aspirin), and sulfonamide antibiotics (such as trimethoprim/sulfamethoxazole).

  • It is essential to consult your doctor before starting any new prescription or over-the-counter medications.

Overdose and Missed Dose

  • Overdose of Insulin Degludec can result in severe hypoglycemia which can lead to unconsciousness, seizures, or even death. In such instances, immediate medical attention is required.

  • If you miss a dose of this medicine, administer it as soon as you remember. However, it should be injected at the same time each day and thus if your next scheduled dose is near, skip the missed dose.

Management of Side Effects

  • Most side effects of Insulin Degludec are temporary and generally resolve when you stop using this medicine. However, if you observe any severe side effects or worsening of any symptoms, please consult your doctor.

  • To manage injection site reactions such as pain or redness at the site of injection, rotate the injection sites within an injection area (upper arm, thigh, or abdomen) from one injection to the next.

  • Experiencing low blood sugar (hypoglycemia) is a common side effect; always carry a quick source of sugar (like candy or fruit juice) with you in case you experience these symptoms.

Use in Driving and Operating Machinery

  • Insulin Degludec is unlikely to affect your ability to drive or operate heavy machinery. However, since hypoglycemia (low blood sugar) can cause dizziness and confusion, avoid driving or using machinery if you experience these symptoms.

Use in Pregnancy and Lactation

  • There are limited data on the use of Insulin Degludec in pregnant women or during lactation. Therefore, consult your doctor before using this medicine during pregnancy and breastfeeding.

Caution in Other Conditions

  • Insulin Degludec should be used with caution in patients with renal or hepatic impairment as insulin requirements may be reduced in these individuals. Close glucose monitoring is recommended in these conditions.

Special Dietary and Lifestyle Recommendations

  • Maintaining a balanced diet that's low in sugar and high in fibre can help manage blood sugar levels.

  • Regular monitoring of blood sugar levels is advisable to ensure the medicine is working effectively.

  • Smoking and alcohol consumption can affect your blood sugar levels and should be avoided.

  • Regular physical activity can help keep your blood sugar levels in check; try to get at least 30 minutes of moderate-intensity exercise most days of the week.

  • It's important to maintain a healthy weight, as being overweight can make it harder to manage your diabetes.

Frequently asked questions

Yes, weight gain is a common side effect of Insulin Degludec, as it is with many types of insulin. However, maintaining a healthy diet and regular physical activity can help manage weight while on this medication.

Yes, Insulin Degludec is a man-made form of a hormone that is naturally produced in the body. It falls into the category of long-acting insulin medications.

There's no direct link between Insulin Degludec and mood changes. However, uncontrolled blood sugar levels as a result of diabetes can sometimes lead to mood swings.

Yes, there is no lactose or lactose-derived products in Insulin Degludec which makes it safe for people with lactose intolerance.

Insulin Degludec does not directly affect your appetite. However, managing your blood sugar levels can help control hunger pangs and prevent overeating.

Yes, hypoglycemia or low blood sugar is a common side effect of many insulins including Insulin Degludec. Regularly monitoring your blood sugar levels can help prevent this.

Abruptly stopping Insulin Degludec without medical advice can lead to high blood sugar levels, which may in turn lead to serious, possibly life-threatening complications.

Terms & Conditions

Available medicines for INSULIN DEGLUDEC
Tresiba Flextouch 100iu Prefilled Pen 3ml
Tresiba Flextouch 100iu Prefilled Pen 3ml
Abbott India Ltd.
Pack of 3 ML
₹1650.70
MRP ₹1942.00
15.00% OFF
Tresiba Penfill 100iu 3ml Pack Of 5 Injections
Tresiba Penfill 100iu 3ml Pack Of 5 Injections
Abbott India Ltd.
Pack of 5 Units
₹6120.00
MRP ₹7200.00
15.00% OFF

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