Lamivudine

Dosage Forms Available

• Lamivudine is available as tablet and solution for oral administration.

Age and Dose Restrictions

• Lamivudine is intended for use in both adults and children.

Contraindications

• Lamivudine is contraindicated in patients with a known hypersensitivity to Lamivudine or any of its components. Patients with severe kidney disease or diabetes must not take this medication unless recommended by their doctor.

Other Medications to Avoid

• Lamivudine can interact with other antiretroviral medicines (e.g., zidovudine, abacavir) and certain hepatitis B medications (e.g., entecavir, telbivudine).

Overdose and Missed Dose

• An overdose of Lamivudine can result in severe nausea, vomiting, or unusual tiredness. If you suspect an overdose, contact your doctor immediately.
• If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• If you experience nausea after taking Lamivudine, try taking it with food.
• Drinking plenty of fluids can help manage diarrhoea or constipation caused by Lamivudine.
• Resting and avoiding strenuous activities can help manage fatigue caused by Lamivudine.

Use in Driving and Operating Machinery

• Lamivudine does not usually affect your ability to drive or operate machines. However, if you feel dizzy, do not drive or operate machines until you feel well again.

Use in Pregnancy and Lactation

• The safety of using Lamivudine during pregnancy is not established. Therefore, it should only be used during pregnancy if the potential benefits outweigh the risks. This medicine can pass into breast milk. Therefore, breastfeeding while using this medication is not recommended.

Caution in Other Conditions

• Caution should be exercised when using Lamivudine in patients with a history of pancreatitis or hepatic impairment because it can worsen these conditions.

Special Dietary and Lifestyle Recommendations

• It is essential to avoid risky behaviours such as sharing needles or having unprotected sex to prevent the spread of HIV or hepatitis B.