Lamivudine + Stavudine

Dosage Forms Available

• Lamivudine + Stavudine is available for oral administration in the form of fixed-dose combination tablets.

Age and Dose Restrictions

• This medicine is meant for use in adults and children above 12 years of age.

Contraindications

• Lamivudine + Stavudine is contraindicated in individuals with known hypersensitivity to any of the components.

• It should not be used by patients with severe liver impairment, active disease of the pancreas (pancreatitis), or advanced peripheral neuropathy.

Other Medications to Avoid

• This medicine may interact with nucleoside reverse transcriptase inhibitors (e.g., didanosine), cytotoxic medications (e.g., doxorubicin), antiviral medications (e.g., ribavirin), and interferon alfa.

• Consult your doctor before starting any new medications, including prescription medcations, over-the-counter medicines, vitamins, and herbal supplements while using Lamivudine + Stavudine.

Overdose and Missed Dose

• Overdose of Lamivudine + Stavudine may result in severe lactic acidosis or liver enlargement. Immediate medical attention is required if symptoms such as unusual muscle pain, fast or irregular heartbeat, severe drowsiness, feeling cold, or shortness of breath occur.

• If you miss a dose of Lamivudine + Stavudine, take it as soon as you remember. However, if it is time for the next dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to make up for a missed dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

• Drinking plenty of fluids can help manage side effects like headache, nausea, and diarrhoea.

• Rest and relaxation may help manage fatigue and malaise.

Use in Driving and Operating Machinery

• Lamivudine + Stavudine may cause dizziness, drowsiness, or fatigue. Avoid driving or operating heavy machinery if you experience these side effects.

Use in Pregnancy and Lactation

• Consult your doctor before using Lamivudine + Stavudine during pregnancy or breastfeeding. Use is advised only if the potential benefits outweigh the risks.

Caution in Other Conditions

• Patients with kidney problems or history of pancreatitis should take caution when taking Lamivudine + Stavudine. Regular monitoring of kidney function and liver enzymes is recommended.

Special Dietary and Lifestyle Recommendations

• Maintain a healthy diet to support immune function.

• Regular moderate exercise can boost your immune system and energy levels.

• If you smoke or consume alcohol, consider stopping or reducing your intake as these may weaken your immune system.

• Attend regular check-ups with your doctor to monitor your health condition.