Home/Drugs By Ailments / Ledipasvir + Sofosbuvir

Ledipasvir + Sofosbuvir

Uses of Ledipasvir + Sofosbuvir

  • Ledipasvir + Sofosbuvir is primarily used for managing chronic hepatitis C virus (HCV) infection. It belongs to the group of antiviral medicines.

  • The medicine is also prescribed to manage HCV genotype 1 infection in patients with advanced liver disease, including decompensated cirrhosis.

Side effects of Ledipasvir + Sofosbuvir

  • Fatigue

  • Headache

  • Nausea

  • Insomnia

  • Diarrhoea

How Ledipasvir + Sofosbuvir works

  • Ledipasvir is classified as an HCV NS5A inhibitor. Simply put, it disrupts the workings of a protein called NS5A in the hepatitis C virus, which is crucial for the virus to multiply and survive.

  • Sofosbuvir is known as a nucleotide analogue NS5B polymerase inhibitor. It mimics the building blocks of the virus's genetic material and gets inserted into it.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Ledipasvir + Sofosbuvir can be taken orally (tablet and oral pellet).

Age and Dose Restrictions

  • This medicine is suitable for adults and children above 12 years of age or weighing at least 35 kg.

Contraindications

  • Ledipasvir + Sofosbuvir is contraindicated in patients with severe renal impairment or end-stage renal disease requiring dialysis.

Other Medications to Avoid

  • Ledipasvir + Sofosbuvir may interact with antibiotics (such as rifampin) and herbal medicines (St. John's wort).

Overdose and Missed Dose

  • If an overdose of Ledipasvir + Sofosbuvir is suspected, seek immediate medical attention.

  • In case of a missed dose, take it as soon as you remember on the same day. However, do not double the dose if it is near the time for your next dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Stay hydrated to manage symptoms such as fatigue and headaches.

  • Rest and relax to help manage fatigue.

Use in Driving and Operating Machinery

  • Ledipasvir + Sofosbuvir may cause dizziness or weakness in some patients. If you experience these side effects, avoid driving or operating heavy machinery until you feel well enough.

Use in Pregnancy and Lactation

  • It is always advised to consult your doctor before using this medicine during pregnancy or breastfeeding.

Caution in Other Conditions

  • Patients with decompensated cirrhosis should exercise caution when taking Ledipasvir + Sofosbuvir.

Special Dietary and Lifestyle Recommendations

  • Regular check-ups with your doctor are recommended to monitor the progress of the disease and the effectiveness of the medication.

Frequently asked questions

No, there are no commonly reported effects of Ledipasvir + Sofosbuvir on mood. However, individual reactions to medicine can vary, and if you notice any unusual changes, consult your doctor.

Yes, Ledipasvir + Sofosbuvir is safe for vegetarians and vegans. This medicine does not contain any animal-derived components.

No, there is no risk of addiction or dependence with Ledipasvir + Sofosbuvir.

It is important to discuss this with your doctor before starting any new medications or supplements, as they may interact with Ledipasvir + Sofosbuvir.

Yes, the duration of treatment with Ledipasvir + Sofosbuvir can range from 12 to 24 weeks, depending on the patient's liver disease status and prior HCV treatment history.

Yes, abruptly stopping any antiviral medication including Ledipasvir + Sofosbuvir can lead to viral resistance or disease relapse. Always follow your doctor’s advice regarding the duration of treatment.

There is no established link between Ledipasvir + Sofosbuvir and weight gain. However, different individuals may experience different side effects. If you notice any sudden, unexplained weight gain, please consult your doctor.

Terms & Conditions


Ledipasvir + Sofosbuvir in other salts

Available medicines for LEDIPASVIR + SOFOSBUVIR
Hepcvir L 400/90 MG Tablet 28
Hepcvir L 400/90 MG Tablet 28
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Pack of 28 Units
₹20500.00
MRP ₹25000.00
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Ledviclear 400/90 MG Tablet 28
Ledviclear 400/90 MG Tablet 28
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MRP ₹27500.00
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Reclaim L 400/90 MG Tablet 28
Reclaim L 400/90 MG Tablet 28
Lupin Ltd
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₹20500.00
MRP ₹25000.00
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Sofab Lp 400/90 MG Tablet 28
Sofab Lp 400/90 MG Tablet 28
Ranbaxy Laboratories Ltd
Pack of 28 Units
₹20500.00
MRP ₹25000.00
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Hepcinat Lp 400/90 MG Tablet 28
Hepcinat Lp 400/90 MG Tablet 28
Natco Pharma Ltd
Pack of 28 Units
₹15170.00
MRP ₹18500.00
18.00% OFF
Ledihep 400/90 MG Tablet 28
Ledihep 400/90 MG Tablet 28
Zydus Cadila
Pack of 28 Units
₹20500.00
MRP ₹25000.00
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Myhep Lvir Tablet 28
Myhep Lvir Tablet 28
Mylan
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₹13120.00
MRP ₹16000.00
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Hepcvir L 400/90 MG Tablet 14
Hepcvir L 400/90 MG Tablet 14
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Pack of 14 Units
₹10496.00
MRP ₹12800.00
18.00% OFF

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