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Lidocaine / Lignocaine + Metronidazole + Sucralfate

Uses of Lidocaine / Lignocaine + Metronidazole + Sucralfate

  • The primary use of Lidocaine / Lignocaine + Metronidazole + Sucralfate lies in the management of various anorectal conditions such as anal fissures, fistulas, and haemorrhoids. It belongs to the group of topical analgesic, antibiotic, and protectant medicines.

  • Apart from managing these specific anorectal conditions, this combination medicine may also be used before or after anal/rectal surgery to prevent infection and promote healing.

Side effects of Lidocaine / Lignocaine + Metronidazole + Sucralfate

  • Burning sensation

  • Stinginess or itchiness

  • Redness or irritation

  • Unusual taste in the mouth

  • Headache

How Lidocaine / Lignocaine + Metronidazole + Sucralfate works

  • Lidocaine / Lignocaine + Metronidazole + Sucralfate is a comprehensive therapeutic combination for anorectal disorders.

  • Lidocaine / Lignocaine is a local anaesthetic. It dulls the pain by blocking nerve signals in the area where it is applied. This results in quick relief from discomfort and pain.

  • Metronidazole is an nitroimidazole antibiotic. It stops the growth of bacteria that can cause infections in the anorectal region, helping to prevent further infection and reduce inflammation.

  • Sucralfate acts as a protectant. It forms a gel-like barrier when it comes into contact with moisture, covering wounded tissues. This protective layer shields the damaged area from irritants, enabling it to heal more effectively. Sucralfate also triggers the production of certain chemicals in the body called prostaglandins and growth factors, which aid in tissue repair.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Lidocaine / Lignocaine + Metronidazole + Sucralfate is available as a cream, ointment or gel for external use.

  • It is applied topically to the affected area around the anus (perianal region).

Age and Dose Restrictions

  • This combination medication is meant for adults and children over 12 years of age.

Contraindications

  • This medicine is contraindicated in patients with known hypersensitivity to lidocaine, other local anaesthetics, or metronidazole.

  • It is also contraindicated in patients with deep wounds or puncture injuries in the application area and active sexually transmitted infections in the application area.

Other Medications to Avoid

  • This combination may interact with other local anaesthetics (such as bupivacaine, ropivacaine), anticoagulants (such as warfarin, heparin), H2 antagonists (like cimetidine, ranitidine), and certain anti-seizure medicines (such as phenytoin, phenobarbital).

Overdose and Missed Dose

  • Overdose of Lidocaine / Lignocaine + Metronidazole + Sucralfate is unlikely as it is intended for external use only. Using the prescribed dosage is recommended to avoid any side effects.

  • If you miss a dose of this medication, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply double the amount to make up for a missed dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage burning, stinging, itching, or dryness at the application site, you can try applying a moisturizer after the medication has been absorbed.

  • To manage rectal irritation or rash, keep the area clean and dry. Avoid the use of harsh soaps or wipes.

  • If you experience a metallic taste in your mouth, drinking plenty of water or chewing sugar-free gum may help.

Use in Driving and Operating Machinery

  • This medication does not usually affect your ability to drive or operate heavy machinery. However, if you feel dizzy or disoriented after applying this medicine, avoid such activities.

Use in Pregnancy and Lactation

  • The use of Lidocaine / Lignocaine + Metronidazole + Sucralfate during pregnancy and breastfeeding is not recommended unless advised by your doctor.

Caution in Other Conditions

  • Patients with severe liver disease should exercise caution when using this combination medication due to metronidazole's known potential for liver toxicity.

Special Dietary and Lifestyle Recommendations

  • Eat a high-fibre diet to prevent constipation, which can worsen anal fissures and haemorrhoids.

  • Avoid straining during bowel movements; take your time.

  • Regularly exercise to promote healthy bowel movements.

  • Avoid sitting for long periods; it can increase pressure on the veins in the anus.

Frequently asked questions

Lidocaine / Lignocaine + Metronidazole + Sucralfate is not directly associated with affecting the menstrual cycle. However, everybody is different and experiences with medications can vary. If you notice any significant changes, please consult your doctor.

Lidocaine / Lignocaine + Metronidazole + Sucralfate is not directly associated with affecting mood swings. However, the relief from pain and discomfort it provides might indirectly improve mood.

While some natural home remedies may provide temporary relief for symptoms of anorectal disorders, Lidocaine / Lignocaine + Metronidazole + Sucralfate is a medical combination specifically designed to manage pain, prevent infection, and promote tissue healing in these conditions. Always consult your doctor before trying alternative remedies.

There is no effect of this combination medication on appetite. However, if you notice any significant changes in appetite while using this medication, please consult your doctor.

No, Lidocaine / Lignocaine + Metronidazole + Sucralfate is not a steroid. It belongs to the group of topical analgesic, antibiotic, and protectant medicines.

Lidocaine / Lignocaine + Metronidazole + Sucralfate provides quick pain relief, but complete healing of the damaged tissue may take several weeks. Always follow your doctor's advice on the duration of use.

No, it is not recommended to cover the treated area with a plastic bandage or dressing unless directed by your doctor.

Terms & Conditions


Lidocaine / Lignocaine + Metronidazole + Sucralfate in other salts

METRONIDAZOLEOFLOXACIN + METRONIDAZOLEMETRONIDAZOLE + NORFLOXACINMETRONIDAZOLE + TETRACYCLINEFURAZOLIDONE + METRONIDAZOLECLINDAMYCIN + CLOTRIMAZOLE + METRONIDAZOLELIDOCAINE / LIGNOCAINE + NIFEDIPINEBECLOMETHASONE DIPROPIONATE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINELIDOCAINE / LIGNOCAINE + PRILOCAINEBENZALKONIUM CHLORIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINEMETRONIDAZOLE + POVIDONE IODINEGABAPENTIN + LIDOCAINE / LIGNOCAINEORNIDAZOLE + POVIDONE IODINE + SUCRALFATEMETRONIDAZOLE + MUPIROCINCIPROFLOXACIN + CLOBETASOL PROPIONATE + METRONIDAZOLE + TERBINAFINECHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINEOXETACAINE + SUCRALFATEPOVIDONE IODINE + SUCRALFATE + TINIDAZOLECHLORHEXIDINE + LIDOCAINE / LIGNOCAINE + SILVER SULFADIAZINESUCRALFATECALAMINE + CETRIMIDE + CHLOROCRESOL + DIMETHICONE + SUCRALFATE + ZINC OXIDECHLORHEXIDINE GLUCONATE + SILVER SULFADIAZINE + SUCRALFATELIDOCAINE / LIGNOCAINE + TETRACAINECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINE + TROXERUTIN + ZINC OXIDECHLORHEXIDINE GLUCONATE + LIDOCAINE / LIGNOCAINE + METRONIDAZOLECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + ZINCCALCIUM DOBESILATE + HYDROCORTISONE ACETATE + LIDOCAINE / LIGNOCAINE + ZINCCLOTRIMAZOLE + LIDOCAINE / LIGNOCAINEPOVIDONE IODINE + SUCRALFATEBECLOMETHASONE DIPROPIONATE + CLOTRIMAZOLE + LIDOCAINE / LIGNOCAINE + OFLOXACINLIDOCAINE / LIGNOCAINE + PHENAZONEBECLOMETHASONE DIPROPIONATE + CHLORAMPHENICOL + CLOTRIMAZOLE + LIDOCAINE / LIGNOCAINEBECLOMETHASONE DIPROPIONATE + CLOTRIMAZOLE + LIDOCAINE / LIGNOCAINE + NEOMYCINLIDOCAINE / LIGNOCAINE + PARADICHLOROBENZENE + TURPENTINE OILBECLOMETHASONE DIPROPIONATE + CLOTRIMAZOLE + GENTAMICIN + LIDOCAINE / LIGNOCAINEBACLOFEN + GABAPENTIN + LIDOCAINE / LIGNOCAINECETRIMIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINE + TANNIC ACIDCHLORHEXIDINE GLUCONATE + METRONIDAZOLEMETRONIDAZOLE + NALIDIXIC ACIDADRENALINE + LIDOCAINE / LIGNOCAINEDOMPERIDONE + SUCRALFATEMETRONIDAZOLE + OFLOXACIN + SIMETHICONEMETRONIDAZOLE + RIFAXIMINALLANTOIN + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + ZINC OXIDECIPROFLOXACIN + METRONIDAZOLEDILOXANIDE + METRONIDAZOLE
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