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Loperamide

ANTIDIARRHOEAL

Uses of Loperamide

  • Loperamide is mainly used to treat short periods of acute diarrhoea. 
  • It is usually prescribed with the oral rehydration salt solution, which compensates for the body's fluid loss and salts during diarrhoea. 
  • Travellers dealing with diarrhoea from dietary changes or contaminated water can also find relief with loperamide. 

Side effects of Loperamide

  • Constipation
  • Dizziness
  • Nausea
  • Headache
  • Flatulence

How Loperamide works

  • Loperamide is a long-acting anti-diarrheal medication. 
  • It works by slowing down the movement of the intestines and reducing the amount of fluid secreted into the gut. This helps to slow down the passage of stool through the colon and allows more time for the body to absorb fluids and electrolytes. As a result, the stool becomes more solid, and bowel movements are less frequent.

Certified content

Written By

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Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available for Loperamide

  • Loperamide can be taken orally (tablet and capsule). 

Age And Dosage Restrictions for Loperamide

  • It is given to adults and children above 12 years of age. 

Contraindications of Loperamide

  • It is contraindicated in patients with a history of hypersensitivity to Loperamide, patients having inflammatory bowel disease, liver disease, or renal impairment.

Medications To Avoid With Loperamide

  • Avoid taking medications for HIV (ritonavir), medications for abnormal heartbeats (quinidine), antifungals (itraconazole), medications for high cholesterol (gemfibrozil), medications for excessive urination (desmopressin), and antiallergics (diphenhydramine) with Loperamide. These medications may alter the safety and effectiveness of Loperamide.

Overdose And Missed Dose

  • Overdose can cause sleepiness, nausea and vomiting, constipation, difficulty passing urine, weak breathing, muscle stiffness and uncoordinated movements. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
  • If you miss a dose of this medicine, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

​​Management Of Side Effects

  • Continue taking the medication as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • This medicine can cause dizziness. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking this medicine. 

Use In Pregnancy And Lactation

  • Loperamide is not recommended in pregnant and breastfeeding women.

Caution In Other Conditions

  • Caution is advised in elderly patients, especially patients with severe diarrhoea, liver and kidney impairment.

Special Dietary And Lifestyle Recommendation

  • Take a balanced diet with adequate fluid and electrolyte intake.
  • Diarrhoea can lead to dehydration and electrolyte imbalances, so it is essential to replenish lost fluids and electrolytes. 
  • Patients should be encouraged to drink water and clear fluids such as broth and sports drinks to maintain hydration. 
  • Additionally, patients should eat foods that are easy to digest and avoid foods that can aggravate diarrhoea, such as spicy or high-fibre foods.
  • One should rest and avoid strenuous physical activity during bouts of diarrhoea. 
  • Additionally, practice good hygiene, such as washing hands frequently and avoiding close contact with others to prevent the spread of infection. 
  • Avoid smoking, as smoking can irritate the digestive tract and worsen diarrhoea.

Frequently asked questions

The first dose of this medicine takes a few minutes to a few hours to act on the intestine's inner lining. 

You should take this medicine with or without a meal, as advised by the doctor. You must complete the course of treatment.

This medicine decreases intestinal movement by acting on the intestinal inner lining. As a result, food travels more slowly through the stomach. The reduced bowel movement makes the food stay longer in the intestine, resulting in increased water absorption and relief of symptoms of diarrhoea.

You can take this medicine with or without meals. Swallow the medicine with a glass of water. 

A single dose of this medicine is effective for about 8–12 hours.

Yes, this medicine is relatively safe if prescribed by a doctor. 

Yes, Loperamide can be used for managing diarrhea associated with Irritable Bowel Syndrome (IBS). It helps by slowing down bowel movements and reducing the frequency of diarrhea.

Loperamide is sometimes used to manage diarrhea during opiate withdrawal, but it does not address other withdrawal symptoms and should not be used as a primary treatment for withdrawal.

Loperamide is not considered addictive when used as directed for diarrhea. However, misuse or taking it in high doses can lead to serious health issues and potentially contribute to dependence.

Taking Loperamide with Cimetidine, an acid reducer, can increase Loperamide levels in the blood. This may enhance its effects and potential side effects, so it's important to use them together only under medical advice.

Terms & Conditions

Available medicines for LOPERAMIDE
Lopamide Tablet 10
Lopamide Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹20.89
MRP ₹25.48
18.00% OFF
Lomofen Plus Tablet 20
Lomofen Plus Tablet 20
Rpg Life Sciences Ltd.
Pack of 20 Units
₹41.00
MRP ₹50.00
18.00% OFF
Lupidium Tablet 10
Lupidium Tablet 10
Lupin Ltd
Pack of 10 Units
₹6.69
MRP ₹13.40
50.10% OFF
Imodium Capsule 4
Imodium Capsule 4
Janssen
Pack of 4 Units
₹15.15
MRP ₹16.90
10.37% OFF
Roko Capsule 10
Roko Capsule 10
Cipla Ltd.
Pack of 10 Units
₹12.71
MRP ₹25.48
50.10% OFF
Eldoper Capsule 15
Eldoper Capsule 15
Micro Labs Ltd
Pack of 15 Units
₹52.07
MRP ₹63.50
18.00% OFF
Eldoper Capsule 10
Eldoper Capsule 10
Micro Labs Ltd
Pack of 10 Units
₹52.07
MRP ₹63.50
18.00% OFF
Ridol Tablet 10
Ridol Tablet 10
Gufic Bioscience Ltd
Pack of 10 Units
₹18.64
MRP ₹22.73
18.00% OFF

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