Loratadine
Uses of Loratadine
Loratadine is primarily used to manage symptoms of allergic conditions such as hay fever (allergic rhinitis) and hives (urticaria). It belongs to the class of medicines known as antihistamines.
In addition to this, this medicine can be used to relieve symptoms associated with other upper respiratory allergies. These symptoms include sneezing, runny nose, itchy or watery eyes, and itching of the nose or throat. It is also used to manage itching and redness caused by chronic idiopathic urticaria.
Side effects of Loratadine
Headache
Drowsiness
Fatigue
Dry mouth
Stomach pain
How Loratadine works
Loratadine is a long-acting antihistamine.
It works by selectively blocking the binding of histamine to H1 receptors. Histamine is a chemical that the body releases during allergic reactions, causing symptoms like itching, sneezing, and watering of the eyes.
By inhibiting the binding of histamine to its receptors, Loratadine ensures that these allergy symptoms are reduced or do not manifest at all. This does not prevent the actual release of histamine from cells but reduces its effects on the body.
Certified content
Written By
MSc (Applied Genetics)
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
- Loratadine is available in several formulations for oral administration. These include regular tablets, orally disintegrating tablets (do not require water to dissolve), liquid syrup, and chewable tablets.
Age and Dose Restrictions
- Loratadine is intended for use in adults and children aged 6 years and older. For individuals under the age of 2 years, this medicine should only be given under the supervision of a doctor.
Contraindications
- Loratadine is contraindicated in patients with hypersensitivity to this medicine or any of its inactive ingredients.
Other Medications to Avoid
- Loratadine may interact with other antihistamines (e.g., diphenhydramine), cough and cold medicines (e.g., acetaminophen, cetrizine), and other central nervous system depressants (e.g., diazepam, clonazepam).
Overdose and Missed Dose
- An overdose of Loratadine, though, unlikely due to its large margin of safety, may cause symptoms such as drowsiness or sleepiness. In children, agitation and increased heart rate have been observed.
- If a dose of Loratadine is missed, it should be taken as soon as it is remembered. However, if it is near the time for the next dose, skip the missed dose and resume the regular dosing schedule.
Management of Side Effects
Most side effects of Loratadine are temporary, generally harmless, and resolve when the medication is discontinued. However, if you experience any severe side effects or worsening of symptoms, please consult your doctor.
- Drinking plenty of fluids can help manage dry mouth.
- Resting or getting a good night's sleep can reduce feelings of fatigue or drowsiness.
Use in Driving and Operating Machinery
- Loratadine may have a minimal effect on the ability to drive or operate machinery. However, if you experience drowsiness, avoid these activities.
Use in Pregnancy and Lactation
- The safety of Loratadine during pregnancy is not yet fully established. It is advised to consult a doctor when considering this medication during pregnancy and lactation.
Caution in Other Conditions
- Patients with liver or kidney impairment should use Loratadine with caution, as they may require a lower dose.
- Also, certain formulations of the medicine may contain sugar and/or aspartame, which could pose a risk to patients with diabetes and phenylketonuria.
Special Dietary and Lifestyle Recommendations
- Minimize exposure to allergens such as pollen, dust mites, and animal dander.
- Keep your home clean and dust-free.
- Maintain good personal hygiene to prevent contact with allergens.
- Use air purifiers in your home to reduce airborne allergens.
- Monitor local weather reports for high pollen count days and stay indoors if possible.
Frequently asked questions
Will Loratadine affect fertility?
No evidence suggests that Loratadine affects fertility in men or women. If you have concerns about this, it is best to consult your doctor.
Are there any particular diet restrictions while taking Loratadine?
There are no specific diet restrictions while taking Loratadine. This medication can be taken with or without food.
Is it safe to take Loratadine daily?
Yes, this medicine can be taken daily for the duration prescribed by your doctor to manage symptoms of allergic conditions.
How much time does Loratadine take to work?
Loratadine starts working within 1-3 hours of taking the medication.
What is the best time to take Loratadine?
Loratadine can be taken any time of the day; however, it is advisable to check with your doctor regarding the optimal time of consumption to benefit from the medication.
What is the duration of treatment with Loratadine?
The duration of treatment with Loratadine varies according to the patient's condition and response to therapy. Always follow your doctor's instructions.
Is Loratadine available over the counter, or do I need a prescription?
Loratadine is available over the counter in many countries but it’s always important to use it under the supervision of a doctor.
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