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Losartan

ANTIHYPERTENSIVE

Uses of Losartan

  • Losartan is primarily used to treat high blood pressure (hypertension) and heart failure. It helps reduce the risk of stroke and other cardiovascular events, such as myocardial infarction, in patients with hypertension. 
  • Additionally, it is effective in managing diabetic nephropathy, which is kidney disease that can occur in patients with type 2 diabetes

Side effects of Losartan

  • Dizziness
  • Stuffy nose 
  • Back pain
  • Upper respiratory tract infections
  • Hypotension
  • Diarrhoea
  • Anaemia
  • Fatigue
  • Hyperkalemia (increased blood potassium levels)

How Losartan works

  • Losartan is an anti-hypertensive agent.
  • It is an Angiotensin II Receptor blocker which acts by preventing the binding of angiotensin II to angiotensin receptors thereby blocking the effect of Angiotensin II (vasoconstriction) This leads to vascular smooth muscle relaxation and lowering of blood pressure. There is an increased blood flow to kidneys which helps in management of Diabetic Nephropathy.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Losartan is available for use via oral (tablet) route.

Age And Dose Restrictions

  • It can be used in adults and children above 6 years of age with appropriate dose calculation.

Contraindications 

  • Losartan use is contraindicated in patients with hypersensitivity to it and in diabetic patients taking Aliskiren. 

Other Medications To Avoid With This Medicine

  • Avoid taking Nonsteroidal anti-inflammatory medications, pain and anti-inflammatory agents, diuretics, lithium, medications for epilepsy, potassium supplements and antibiotics.

Overdose And Missed Dose

  • If a dose is missed, it should be taken if there is a time gap from the subsequent dose. If not, then a routine dosing regimen should be followed
  • Overdose symptoms of losartan will include hypotension, tachycardia or bradycardia. Inform your doctor about these effects and follow the instructions accordingly.

Management Of Side Effects

  • Take this medicine with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment. To avoid falls and injuries, sit down or lie down as soon as you feel dizzy. move carefully, when rising from a sitting or sleeping posture.

Use In Driving And Operating Machinery

  • This medicine can cause dizziness and drowsiness. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking this medicine. 

Use In Pregnancy And Lactation

  • Losartan is notrecommended for use in Pregnant and Lactating females.

Caution In Other Conditions

  • Caution is advised for use of Losartan in patients with liver disease and those with reduced kidney function.

Special Dietary And Lifestyle Recommendation

  • Alcohol consumption should be avoided when using losartan.
  • Monitor the renal function and potassium levels periodically as per doctor's instructions while using Losartan.
  • Individuals with hypertension and coronary artery disease should consider lifestyle modifications, including dietary changes such as a low-sodium, low-carbohydrate, and low-fat diet. Regular exercise, like brisk walking for at least 30 minutes daily, five days a week, is also recommended to control blood pressure.
  • Patients with hypertension are at a continuous risk of heart attacks and strokes. Hence, it is crucial to establish a routine for monitoring blood pressure through a digital blood pressure monitoring device at home or regular visits to the doctor.
  • Proper education on recognising the signs and symptoms of heart attacks and strokes is essential. This knowledge can lead to quicker interventions, minimising complications and ultimately promoting a faster and more complete recovery. 

Frequently asked questions

No. Losartan is not safe for use in pregnancy.

The average time taken to show the action by losartan is 60 minutes. But it may vary, from individual to individual.

No. Losartan is not recommended for use in breastfeeding females. 

Yes. Losartan can cause dizziness as a side effect in some patients.

No, Losartan does not affect fertility but can potentially cause fetal malformations and therefore is not recommended for use in pregnancy.

Yes. Losartan can cause Hyperkalemia (increased potassium levels in the blood.

Yes. Losartan use can cause weight gain in some patients.. 

It is recommended to stop taking alcohol while taking losartan tablets. 

Yes. Losartan can cause Bradycardia (reduced heart rate) in some patients.

Terms & Conditions


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