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Magnesium Valproate

Uses of Magnesium Valproate

  • Magnesium Valproate is primarily used for the management of epilepsy and bipolar disorder, and for the prevention of migraines. It belongs to the class of medicines known as anticonvulsants and mood stabilisers.

Side effects of Magnesium Valproate

  • Nausea and vomiting

  • Diarrhoea

  • Abdominal pain

  • Dizziness

  • Drowsiness

How Magnesium Valproate works

  • Magnesium Valproate is an anticonvulsant and a mood stabiliser. It works primarily by increasing the levels of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain.

  • GABA has a calming effect on our brains. It slows down overactive brain signals, helping to reduce seizures, stabilise moods, and prevent migraines.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage forms available

  • Magnesium Valproate is available for oral administration in the form of tablets, extended-release tablets and syrup.

Age and dose restrictions

  • This medicine is meant for use in adults only. The use of Magnesium Valproate is not approved for children or teenagers under 18 years of age.

Contraindications

  • Magnesium Valproate is contraindicated in patients with hypersensitivity to any components of the medicine.

  • It is also contraindicated in patients diagnosed with liver disease, urea cycle disorders, or mitochondrial disorders caused by mutations in mitochondrial DNA polymerase γ (POLG).

Other medications to avoid

  • Magnesium Valproate may interact with medications pain relievers and anti-inflammatory medicines (such as aspirin), benzodiazepines (sedatives like diazepam and alprazolam), carbapenems (antibiotics like meropenem and ertapenem), an anticonvulsant (like lamotrigine) and blood thinner (like warfarin).

Overdose and missed dose

  • Overdosing on Magnesium Valproate may lead to serious complications such as confusion, loss of consciousness, or life-threatening heart problems. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose of Magnesium Valproate, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Management of side effects

Most side effects of Magnesium Valproate are temporary and generally harmless, resolving once the medication is discontinued. However, if you experience any severe side effects or worsening of symptoms, please consult your doctor. Here are some tips for managing side effects:

  • If you experience nausea or vomiting, try taking the medication with meals.

  • Drinking plenty of water can help reduce the risk of dehydration from diarrhoea.

  • Regular rest techniques can help manage dizziness and drowsiness.

Use in driving and operating machinery

  • Magnesium Valproate may cause drowsiness or dizziness. If you experience these side effects, avoid driving or operating heavy machinery until you feel alert and safe to do so.

Use in pregnancy and lactation

  • It is recommended to consult your doctor before taking Magnesium Valproate during pregnancy or while breastfeeding, as this medicine may have potential risks.

Caution in other conditions

  • Patients with existing liver conditions should exercise caution when taking Magnesium Valproate as it has been linked to potential liver damage.

  • Regular monitoring of liver function is recommended for such patients while on this medication.

Special dietary and lifestyle recommendations

  • A balanced diet can help support overall health and well-being while managing conditions like epilepsy, bipolar disorder, and migraines.

  • Adequate sleep is crucial for controlling seizures and managing mood swings associated with bipolar disorder.

  • Reducing stress through relaxation techniques such as meditation or yoga can be beneficial for managing these conditions.

  • Avoiding triggers known to provoke seizures or migraines, such as excessive caffeine or alcohol, can be helpful in managing these conditions.

Frequently asked questions

No, Magnesium Valproate is not a steroid. This medicine is an anticonvulsant and mood stabiliser.

Magnesium Valproate can cause drowsiness as one of its side effects. If you experience excessive sleepiness or drowsiness while taking this medicine, you should consult your doctor immediately.

Magnesium Valproate is not directly associated with affecting fertility in men or women. However, if you are planning to conceive, you should discuss this with your doctor before starting on this medication.

Yes, it is safe to take Magnesium Valproate daily as long as it is prescribed by your doctor. The dosage and frequency of this medicine are usually determined by your health condition and response to treatment.

The onset of action for Magnesium Valproate varies depending on the condition being treated and individual response, but generally the therapeutic effect may start within a week of treatment and become fully apparent after several weeks.

Magnesium Valproate is a prescription medication and it is not available over the counter. You must have a valid prescription from a doctor to obtain this medicine.

There are no natural alternatives that have been demonstrated to have the same clinical efficacy as Magnesium Valproate for managing conditions such as epilepsy and bipolar disorder. Any change or cessation in treatment should only occur under medical supervision.

Terms & Conditions

Available medicines for MAGNESIUM VALPROATE
Macorate Cr 300 Tablet 10
Macorate Cr 300 Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹91.84
MRP ₹112.00
18.00% OFF
Magprol Cr 500 Tablet 10
Magprol Cr 500 Tablet 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹116.44
MRP ₹142.00
18.00% OFF
Macorate Cr 200 Tablet 10
Macorate Cr 200 Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹59.86
MRP ₹73.00
18.00% OFF
Macorate Cr 400 Tablet 10
Macorate Cr 400 Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹98.40
MRP ₹120.00
18.00% OFF
Magprol Cr 300 Tablet 10
Magprol Cr 300 Tablet 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹77.08
MRP ₹94.00
18.00% OFF
Magprol Cr 400 Tablet 10
Magprol Cr 400 Tablet 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹106.60
MRP ₹130.00
18.00% OFF
Magprol Cr 200 Tablet 10
Magprol Cr 200 Tablet 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹57.40
MRP ₹70.00
18.00% OFF
Macorate Cr 500 Tablet 10
Macorate Cr 500 Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹123.00
MRP ₹150.00
18.00% OFF

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