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Mefloquine

Uses of Mefloquine

  • Mefloquine is primarily used for the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax, and it belongs to the antimalarial medications.

Side effects of Mefloquine

  • Nausea and vomiting

  • Stomach pain

  • Diarrhea

  • Dizziness and loss of balance

  • Trouble sleeping

How Mefloquine works

  • Mefloquine is an antimalarial medicine.

  • It works by killing malaria parasites present in the blood. Mefloquine concentrates within the food vacuoles of these parasites and interrupts their ability to digest their food, hence inhibiting their standard growth and replication. This process helps to manage and eradicate the malarial infection.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Mefloquine is available in tablet form for oral administration.

Age and Dose Restrictions

  • Mefloquine is intended for both adults and children above 6 months of age.

Contraindications

  • Mefloquine is contraindicated in individuals with a known allergy to Mefloquine or any components of its formulation.

  • This medicine is not advisable for individuals with severe psychiatric disorders, such as severe depression and anxiety disorders.

  • It is also contraindicated in patients with epilepsy or other seizure disorders and severe liver disease.

Other Medications to Avoid

  • Mefloquine may interact with other antimalarial medications (eg., chloroquine and quinine), antiarrhythmics (eg., amiodarone), anticonvulsants (eg., valproic acid), certain antibiotics (eg., rifampin), and blood thinners (eg., warfarin).

Overdose and Missed Dose

  • Overdosing on Mefloquine might lead to symptoms such as nausea, vomiting, vision changes, seizures and heart rhythm disturbances. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose of Mefloquine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of fluids can help manage side effects like nausea and vomiting.

  • Resting and avoiding sudden movements can minimise dizziness and loss of balance.

  • Maintaining a regular sleep routine can help manage sleep disturbances.

Use in Driving and Operating Machinery

  • Mefloquine might impair your ability to drive or operate heavy machinery due to side effects like dizziness and vision changes. If you experience these side effects, avoid driving or operating heavy machinery until the effects subside.

Use in Pregnancy and Lactation

  • Mefloquine can be used during pregnancy if the potential benefit outweighs the risks. It is also considered compatible with breastfeeding. However, always consult your doctor before using this medication if you're pregnant or nursing.

Caution in Other Conditions

  • Individuals with a history of psychiatric conditions, liver disease, seizure disorders, or heart rhythm disorders should exercise caution while taking Mefloquine.

Special Dietary and Lifestyle Recommendations

  • Maintain a healthy diet to support overall health and recovery.

  • Ensure adequate hydration, especially in hot weather or when exercising.

  • Follow guidelines for preventing mosquito bites while in malaria-endemic areas, such as wearing long-sleeved clothing, sleeping under mosquito nets, and using insect repellents.

Frequently asked questions

Mefloquine has a long half-life of around 14-41 days, which means it stays in the body for a considerable period after administration.

Mefloquine can potentially have psychiatric side effects, including symptoms such as severe anxiety, paranoia, depression, hallucinations and even suicidal thoughts. If you experience any of these symptoms, seek medical attention immediately.

There is no known risk of addiction or dependency associated with the use of Mefloquine. It is an antimalarial medication, not a psychoactive substance.

There is no specific time of day to take Mefloquine. However, following a regular schedule can help ensure that you do not miss a dose.

You need a prescription to obtain Mefloquine as it is not available over the counter.

Mefloquine is usually taken for malaria management and as prescribed by the doctor for treatment. It is important to follow your doctor's advice regarding the dosage and frequency.

No, Mefloquine is not a steroid. It is an antimalarial medication used to both prevent and treat malaria.

Terms & Conditions


Mefloquine in other salts

Available medicines for MEFLOQUINE
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Mefloc 250 MG Tablet 4
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Mefex 250 MG Tablet 6
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Mefliam 250 MG Tablet 6
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Larimef Tablet 6
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