Metformin + Pioglitazone + Teneligliptin

Dosage Forms Available

• Metformin + Pioglitazone + Teneligliptin is available in tablet form.

• It is administered orally, typically taken with meals to enhance absorption and minimize gastrointestinal discomfort.

Age and Dose Restrictions

• This medicine is intended for use by adults only. It is not recommended for children or adolescents.

Contraindications

• Metformin + Pioglitazone + Teneligliptin is contraindicated in patients with severe renal impairment, end-stage renal disease, or those undergoing dialysis.

• It is also contraindicated in patients with acute or chronic metabolic acidosis, including diabetic ketoacidosis.

• Patients with a history of bladder cancer should avoid this medication due to the risks associated with Pioglitazone.

Other Medications to Avoid

• This combination may interact with certain medications, including diuretics (like furosemide), corticosteroids (such as prednisone), and beta-blockers (like propranolol). These interactions can potentially affect blood glucose control, either by increasing or decreasing the effectiveness of the diabetes management regimen, and may require closer monitoring for hypoglycemia or hyperglycemia.

Overdose and Missed Dose

• An overdose of Metformin + Pioglitazone + Teneligliptin might lead to severe hypoglycemia, lactic acidosis, or other metabolic disturbances. Immediate medical attention is crucial in the event of an overdose.

• If you miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage nausea, try taking the medication with food or at night.

• In cases of mild hypoglycemia symptoms, consuming a fast-acting source of sugar like glucose tablets can help.

Use in Driving and Operating Machinery

• This medication may affect your ability to drive or operate machinery. If you experience dizziness or drowsiness after taking Metformin + Pioglitazone + Teneligliptin, avoid driving or engaging in any potentially hazardous activities.

Use in Pregnancy and Lactation

• Metformin is generally considered safe during pregnancy; however, the safety of Pioglitazone and Teneligliptin has not been fully established. This combination should only be used if the potential benefits outweigh the risks.

• Consult your doctor before using this medication during pregnancy or while breastfeeding.

Caution in Other Conditions

• Patients with impaired liver function or congestive heart failure should use Metformin + Pioglitazone + Teneligliptin with caution. Regular monitoring of liver enzymes and cardiac function may be necessary.

• Caution is also advised for elderly patients due to the increased risk of adverse effects such as lactic acidosis or heart failure.

Special Dietary and Lifestyle Recommendations

• Maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins to help manage type 2 diabetes. Avoid excessive sugary and fatty foods.

• Regular physical activity can significantly improve blood glucose control. Aim for at least 150 minutes per week of moderate aerobic activity or 75 minutes per week of vigorous activity.

• Monitor blood glucose levels regularly as advised by your doctor to ensure effective management of diabetes.

• Stay hydrated by drinking plenty of water throughout the day, as dehydration can affect blood sugar levels.

• Manage stress through techniques such as yoga, meditation, or deep breathing exercises. Stress can impact glucose metabolism and diabetes management.