Metformin + Pioglitazone + Voglibose

Dosage Forms Available

• Metformin + Pioglitazone + Voglibose is available for oral use in the form of tablets.

Age and Dose Restrictions

• This medicine is meant for adults of age above 18 years. It is not recommended for use in children and adolescents.

Contraindications

• This combination therapy is contraindicated in patients with type 1 diabetes.

• Individuals with diabetic ketoacidosis must avoid it.

• Patients with severe renal impairment should not take this medication.

• Those with known hypersensitivity to metformin, pioglitazone, or voglibose should also not use this combination.

Other Medications to Avoid

• Metformin + Pioglitazone + Voglibose may interact with insulin, sulfonylureas (such as gliclazide and glipizide), cationic medicines (like cimetidine, amiloride, and digoxin), CYP2C8 inhibitors (such as gemfibrozil) and CYP2C8 inducers (like rifampicin).

Overdose and Missed Dose

• An overdose of Metformin + Pioglitazone + Voglibose may cause hypoglycaemia or lactic acidosis. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Gastrointestinal side effects can be managed by taking the medication with meals.

• For managing headaches, taking rest and staying hydrated can be helpful.

Use in Driving and Operating Machinery

• Metformin + Pioglitazone + Voglibose does not usually affect your ability to drive or operate machinery. However, if you experience dizziness or blurred vision after taking this medicine, avoid driving or operating machinery.

Use in Pregnancy and Lactation

• Metformin + Pioglitazone + Voglibose should be used during pregnancy and breastfeeding only if the potential benefits justify the potential risk to the foetus or child. It is advisable to consult your doctor before using this medicine during these periods.

Caution in Other Conditions

• Patients with congestive heart failure and hepatic impairment should use Metformin + Pioglitazone + Voglibose with caution and under regular monitoring.

Special Dietary and Lifestyle Recommendations

• Smoking cessation and limiting alcohol intake can help manage the symptoms of type 2 diabetes.

• Regular check-ups with your doctor are beneficial in tracking your progress and adjusting your medication if needed.