Methylcobalamin + Nicotinamide + Vitamin B6 / Pyridoxine is primarily used to prevent or manage nutritional deficiencies and belongs to the group of essential nutrient supplements.
It is also indicated for certain health conditions, such as cognitive disorders (Alzheimer's disease, dementia), cardiovascular diseases, metabolic disorders (homocystinuria), skin conditions (acne, psoriasis), and peripheral neuropathy.
Gastrointestinal disturbances
Headache
Skin flushing
Allergic reactions
Sensory neuropathy
Methylcobalamin, a form of vitamin B12, acts as a catalyst for the enzyme methionine synthase, which helps convert homocysteine into methionine. This process is important for the production of red blood cells and maintaining the health of the nervous system.
Nicotinamide, a form of vitamin B3, is a precursor to two essential coenzymes, nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate. These coenzymes are involved in many bodily processes, including energy production, DNA repair, and cellular signalling.
Pyridoxine, or vitamin B6, is transformed into the biologically active form pyridoxal 5'-phosphate (PLP). As a coenzyme, PLP aids a variety of enzymes involved in amino acid metabolism, neurotransmitter synthesis, and heme biosynthesis. Heme is a vital component of haemoglobin, which carries oxygen in our blood.
BDS, MDS
Bachelor of Dental Surgery
Dosage Forms Available
Methylcobalamin + Nicotinamide + Vitamin B6 / Pyridoxine is available as tablets, capsules, and injectable solutions for oral administration.
The injectable solutions are administered via the intramuscular route.
Age and Dose Restrictions
This medicine is meant for use in adults and children.
Contraindications
Methylcobalamin + Nicotinamide + Vitamin B6 / Pyridoxine is contraindicated in individuals with hypersensitivity to any of its components.
Other Medications to Avoid
This combination may interact with anti-diabetic medications (such as glimepiride and metformin), anticonvulsants (like carbamazepine and phenobarbital), and blood pressure medications (such as beta blockers and ACE inhibitors).
Overdose and Missed Dose
An overdose of Methylcobalamin + Nicotinamide + Vitamin B6 / Pyridoxine might lead to symptoms like headache or gastrointestinal disturbances. If an overdose is suspected, it is crucial to consult a doctor immediately.
If you miss a dose of this medicine, take it as soon as you remember, unless it is nearly time for the next dose. In that case, skip the missed dose and continue with your regular dosing schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If experiencing nausea, try taking this medicine with food or after meals.
For headaches, ensure adequate hydration and rest.
Use in Driving and Operating Machinery
There is no indication that Methylcobalamin + Nicotinamide + Vitamin B6 / Pyridoxine affects the ability to drive or operate machinery. However, monitor how you feel after taking it before engaging in such activities.
Use in Pregnancy and Lactation
Consult your doctor before using Methylcobalamin + Nicotinamide + Vitamin B6 / Pyridoxine during pregnancy and lactation. The safety of this medicine in these conditions should be assessed by a healthcare provider.
Caution in Other Conditions
Patients with kidney disorders should use Methylcobalamin + Nicotinamide + Vitamin B6 / Pyridoxine cautiously. Impaired renal function may affect the elimination of the vitamins, leading to potential accumulation.
Special Dietary and Lifestyle Recommendations
Maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins to support overall health while managing conditions related to vitamin deficiencies.
Regular physical activity can help improve circulation and overall health, potentially mitigating some symptoms related to peripheral neuropathy.
Managing stress through relaxation techniques like yoga or meditation can be beneficial for cognitive health and general well-being.
Frequently asked questions
No, Methylcobalamin + Nicotinamide + Vitamin B6 / Pyridoxine is not a steroid. It is a combination of essential nutrients, primarily used as a dietary supplement.
Yes, this combination plays important roles in the synthesis of various neurotransmitters that regulate mood and cognitive function.
There is no direct evidence to suggest that this combination affects menstruation. However, if you notice any changes in your menstrual cycle while taking this supplement, it is advisable to consult your doctor.
Yes, apart from managing nutritional deficiencies, this combination is also used off-label for conditions like Alzheimer's disease and dementia as well as skin conditions like acne and psoriasis.
Yes, these vitamins can be manufactured synthetically and are usually vegan-friendly. However, it is advisable to check the product label or consult with the manufacturer to confirm
No, this vitamin combination does not have addictive properties. However, long-term use should always be under the supervision of a doctor.
No, these essential nutrients do not lead to dependency or withdrawal symptoms. However, excessive or prolonged consumption can lead to certain side effects, such as sensory neuropathy.
Methylcobalamin + Nicotinamide + Vitamin B6 / Pyridoxine in other salts
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