The primary use of Methylcobalamin + Nicotinamide + Vitamin B6 (Pyridoxine) is to manage vitamin B12, B3 and B6 deficiencies and related conditions like pernicious anaemia, pellagra, and pyridoxine-dependent seizures. It belongs to the group of essential B-vitamin supplements.
In addition, this combination is used to manage peripheral neuropathy caused by diabetes, alcoholism, or certain medications, lower homocysteine levels in the blood to reduce cardiovascular disease risk and support nervous system health and cognitive functions.
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Methylcobalamin is the biologically active form of Vitamin B12. It acts as a coenzyme for methionine synthase, an enzyme vital for DNA and protein synthesis. It also aids in red blood cell formation and the maintenance of nerve cells.
Nicotinamide, also known as Vitamin B3, is a precursor of NAD and NADP, which are coenzymes essential for cell metabolism and energy production. It also helps to regulate inflammation within the body.
Pyridoxine, or Vitamin B6, is transformed in the body into Pyridoxal 5'-Phosphate (PLP), a coenzyme participating in numerous metabolic reactions, neurotransmitter synthesis, and amino acid metabolism. When combined, these vitamins play complementary roles in maintaining overall health, particularly neurological health, and metabolic processes.
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Methylcobalamin + Nicotinamide + Vitamin B6 (Pyridoxine) can be taken orally in the form of tablets and capsules.
The combination is also available in liquid form for oral administration or nasogastric tube feeding.
For parenteral use, it is available as a solution for intramuscular, subcutaneous or slow intravenous injection.
This combination is suitable for adults and children above 12 years of age.
This medicine is contraindicated if you have a known hypersensitivity to any of the vitamins included in the combination.
People with abnormal red blood cells (megaloblastic anaemia) that are not caused by vitamin B12 deficiency should also avoid this medication.
This combination can interact with antibiotics (such as tetracyclines and quinolones), anticonvulsants (like phenytoin and carbamazepine), chemotherapy medicines (such as methotrexate and leflunomide), proton pump inhibitors (like omeprazole and rabeprazole) and certain antidiabetic medicines (such as metformin and dapagliflozin).
An overdose of Methylcobalamin + Nicotinamide + Vitamin B6 (Pyridoxine) may cause symptoms like nausea, vomiting, diarrhoea, and flushing of the skin. If you observe these symptoms, inform your doctor immediately.
If you forget to take your dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water may help manage nausea and vomiting.
Taking the medication after meals can reduce stomach upset.
This medicine may cause dizziness or drowsiness. It is advised to avoid driving or operating heavy machinery until you know how the medicine affects you.
The use of Methylcobalamin + Nicotinamide + Vitamin B6 (Pyridoxine) during pregnancy and breastfeeding should only be under medical supervision. Always consult your doctor before starting any medication.
Caution is advised in individuals with kidney disease, as these vitamins can accumulate in the body.
High-dose nicotinamide may worsen conditions like liver disease, peptic ulcers, and gallbladder issues.
Regular consumption of foods rich in B vitamins such as lean meats, eggs, dairy products, leafy greens, seeds and nuts can help maintain a healthy level of these vitamins in your body.
Regular exercise can also aid overall health and well-being.
Frequently asked questions
While not common, it is possible to have an allergic reaction to this combination. Symptoms may include skin rash, itching or swelling, severe dizziness and trouble breathing. If you experience these or any other unusual symptoms, contact your doctor immediately.
No, these vitamins usually don't directly affect appetite, but deficiencies can cause fatigue, weakness, and appetite loss. Correcting a deficiency may indirectly boost appetite by improving energy and well-being. If your appetite changes significantly while taking these supplements, consult your healthcare provider.
Yes, Methylcobalamin + Nicotinamide + Vitamin B6 (Pyridoxine) is usually given on prescription by a doctor. It is not typically available over the counter.
This combination should be taken under medical supervision. Though these are essential vitamins, excessive amounts can lead to side effects and interactions with other medications.
The onset of effect can vary depending on individual absorption rates, the severity of the deficiency, and other factors. Consult your doctor for detailed information.
Methylcobalamin + Nicotinamide + Vitamin B6 (Pyridoxine) is not directly associated with affecting mood or emotions. However, if you notice any unusual changes, consult your doctor.
No, Methylcobalamin + Nicotinamide + Vitamin B6 (Pyridoxine) is not a steroid. It is a combination of essential B vitamins used to manage certain vitamin deficiencies and related conditions.
Methylcobalamin + Nicotinamide + Vitamin B6 (pyridoxine) in other salts
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