Metoprolol Succinate

Dosage Forms Available

• Metoprolol Succinate is available for oral use (extended-release tablets).

Age and Dose Restrictions

• This medicine is meant for adults above 18 years of age. Safety and effectiveness in paediatric patients have not been established.

Contraindications

• Metoprolol Succinate is contraindicated in patients with known allergies to it or any of its constituents.
• It is also contraindicated in patients with cardiogenic shock, severe bradycardia, heart block greater than first-degree, sick sinus syndrome, and decompensated heart failure.

Other Medications to Avoid

• This medicine may interact with CYP2D6 inhibitors (such as paroxetine and fluoxetine), catecholamine-depleting medicines (such as reserpine and guanethidine), and antidiabetic agents (like insulin and metformin).

Overdose and Missed Dose

• An overdose of this medication may cause severe hypotension, bradycardia, heart failure, cardiogenic shock, and cardiac arrest. If you observe any of these symptoms, inform your doctor immediately.
• If you forget to take your dose of Metoprolol Succinate, take it as soon as you remember. However, do not double up on the dose if it is nearly time for your next scheduled dose.

Management of Side Effects

Most side effects are temporary, generally harmless, and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water and including more fibre in your diet will help manage side effects like constipation.
• If you feel nauseous after taking this medicine, taking it with food or a snack might help.

Use in Driving and Operating Machinery

• This medicine may cause dizziness and fatigue, affecting your ability to drive or operate heavy machinery. It is best to avoid these activities until you know how Metoprolol Succinate affects you.

Use in Pregnancy and Lactation

• Metoprolol Succinate should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus.
• As Metoprolol is passed into human milk, caution should be exercised when using this medicine during breastfeeding.

Caution in Other Conditions

• Patients with liver impairment should exercise caution when taking this medicine, as dose adjustment may be required.
• It should also be used with caution in patients with peripheral arterial circulatory disorders, pre-existing conduction disorders, and those at risk of hypoglycemia or hyperthyroidism.

Special Dietary and Lifestyle Recommendations

• Following a diet low in salt and avoiding high-cholesterol foods can help manage high blood pressure and heart conditions.
• Regular moderate-intensity exercise like walking or cycling can help improve blood pressure, heart health, and overall fitness.