Miconazole + Mometasone + Nadifloxacin is a combination medicine primarily used to manage mixed skin infections involving fungal organisms like dermatophytes and yeasts, along with susceptible bacterial strains. It belongs to the group of antifungal, corticosteroid, and antibiotic medicines.
Additionally, it is effective against superficial mycoses such as dermatophytosis, cutaneous candidiasis, pityriasis versicolor complicated by secondary bacterial infections, and inflammatory conditions like seborrhoeic dermatitis.
Burning or stinging sensation at the application site
Itching
Irritation
Redness (erythema)
Dryness
Scaling
Peeling of skin
Miconazole + Mometasone + Nadifloxacin is an antifungal, steroidal and antibacterial combination.
Miconazole acts as an antifungal agent stopping the growth of fungi. It achieves this by inhibiting the production of a substance called ergosterol, that's crucial for the structure of fungal cell membranes. Lack of ergosterol disrupts the cell membranes, causing leakage of cellular contents and leading to the death of the fungi.
Mometasone is a corticosteroid. It works by binding to certain receptors inside cells and changing the way these cells behave. This in turn results in reduced production of substances that trigger inflammation, itching, redness, and swelling in the skin.
Nadifloxacin, being a fluoroquinolone antibiotic, targets bacteria causing infections. It interferes with two important bacterial enzymes called DNA gyrase and topoisomerase IV. By disrupting these enzymes, it hinders bacterial DNA replication process, thereby killing the bacteria and clearing up the infection.
The combined action of these three components facilitates comprehensive management of mixed skin infections involving both fungi and bacteria.
MSc (Applied Genetics)
BMS, FMC, MD Resident
Miconazole + Mometasone + Nadifloxacin is available as a topical medication in the form of a cream, lotion, or ointment.
These are all designed for external use on the skin.
The medicine is mostly intended for use in adults.
However, it can also be used in children, teenagers, and the elderly if prescribed by a doctor.
This medicine should not be used by individuals with a known allergy to miconazole, mometasone or nadifloxacin.
This combination may interact with other topical products including corticosteroids (e.g., hydrocortisone) and other antifungals (e.g., clotrimazole).
Before starting any prescription or over-the-counter medications, it is crucial to consult your doctor.
Overdose of this combination medication is unlikely as it is intended for external use only. Using the prescribed dosage is recommended to avoid any side effects.
If you forget to apply this medicine, do so as soon as you remember. However, if it is nearly time for the next application, skip the missed dose and continue on your regular schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage skin dryness or irritation caused by this medication, use a gentle, fragrance-free moisturiser.
Reducing the frequency of application may also help manage these side effects.
Miconazole + Mometasone + Nadifloxacin is applied topically and should not affect your ability to drive or operate heavy machinery.
The safety of this medicine for use in pregnancy and breastfeeding has not been established.
It is advised to consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding, before using this medicine.
Patients with extensive skin injuries or burns should exercise caution when applying this medication due to the possibility of increased absorption leading to systemic effects.
To help prevent fungal and bacterial infections, maintain good personal hygiene.
Regularly clean and dry the affected areas of skin, particularly if they are prone to sweating.
Avoid tight-fitting clothes that can cause chafing and increase the risk of skin infections.
Follow a balanced diet to keep your immune system strong and better able to fight off skin infections.
Frequently asked questions
You may observe improvement in symptoms within 1-2 weeks of regular use. Complete healing may take between 2-4 weeks. If no improvement is seen after 2 weeks, it is advisable to consult your doctor.
This combination medicine is usually safe to use on the face. However, avoid using this around the eyes, mouth, and nostrils unless directed by a doctor.
The safety and efficacy of this combination in children have not been firmly established. Therefore, it should be used with caution and only under a paediatric prescription.
The safety of this combination during pregnancy has not been conclusively established. It is wise to consult your doctor before using this medication, to appraise yourself of the potential benefits and risks of using this medication.
Acne is not a known side effect of this combination. However, if you notice any worsening of acne or any new skin reactions while using this medicine, consult your doctor.
Nadifloxacin, one of the components of this combination, may cause photosensitivity or increased sensitivity to sunlight. Thus, it is advisable to avoid sun exposure and use sun protection while using this medicine.
It is generally advisable to avoid heavy cosmetics on the area of the skin being treated. Cosmetics may interfere with the medicine's ability to work and may also increase the risk of skin irritation.
Miconazole + Mometasone + Nadifloxacin in other salts
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