Mifepristone + Misoprostol
ABORTIFACIENTUses of Mifepristone + Misoprostol
- Mifepristone + Misoprostol is used for the medical termination of pregnancy. This combination is effective for pregnancies up to 70 days from the first day of the last menstrual period. Mifepristone works by blocking the hormone needed to sustain pregnancy, while Misoprostol helps complete the termination process.
Side effects of Mifepristone + Misoprostol
- Uterine contractions or lower abdominal cramps
- Fetal malformations/birth defects
- Heavy bleeding
- Gastrointestinal cramping
- Nausea
- Vomiting
- Diarrhoea
How Mifepristone + Misoprostol works
- Mifepristone is an anti-hormone that blocks the effects of the progesterone hormone. This hormone is required to continue the pregnancy.
- Misoprostol is a prostaglandin. It helps in the contraction of the womb to expel the pregnancy from the womb.
- Together, both combine and act to terminate the pregnancy.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Mifepristone + Misoprostol can be taken orally (tablet, kit).
Age And Dose Restrictions
- This combination is not intended to be used for children. It is only recommended for adult females when prescribed by a doctor.
Contraindications
- This combination is contraindicated in patients with a history of mifepristone or misoprostol, females with ectopic pregnancy, bleeding disorders, asthma, porphyrias, adrenal disorder and liver disease.
Other Medications To Avoid With This Medicine
- Avoid taking anticoagulants (warfarin), antifungals (ketoconazole), corticosteroids (prednisone), and anticonvulsants (phenobarbital) with this combination. These medications may alter the safety and efficacy of Mifeprisonte + Misoprostol.
Overdose And Missed Dose
- In case of an overdose, contact the nearest hospital or your doctor immediately.
Management Of Side Effects
- Continue taking the combination as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.
Use In Driving And Operating Machinery
- This combination may make you feel dizzy. Do not drive or use machinery or work that requires your focus.
Use In Pregnancy And Lactation
- Failure to terminate a pregnancy after taking mifepristone as the first medicine while taking misoprostol in combination medicine is a 3-times risk of birth defects. This combination is not recommended for breastfeeding women.
Caution In Other Conditions
- This combination is not recommended in patients with liver or kidney diseases.
Special Dietary And Lifestyle Recommendation
- Maintain a healthy diet of fruits, vegetables, and whole grains to support overall well-being.
- Stay hydrated by drinking an adequate amount of water throughout the day.
- Get regular exercise to promote good health and boost your immune system.
- Avoid smoking and limit alcohol consumption for better health outcomes.
- Take sufficient rest and manage stress levels effectively.
Frequently asked questions
1. When should you not be using Mifepristone + Misoprostol?
Do not use this combination if your pregnancy is not confirmed or if your doctor suspects an extra-uterine pregnancy, severe asthma, which cannot be treated with medications, hereditary porphyrias and chronic adrenal failure.
2. Can you use Mifepristone + Misoprostol in liver diseases?
Be cautious about the use of liver disease while taking this combination.
3. Can you use Mifepristone + Misoprostol for kidney diseases?
Be cautious about the use of this combination in patients with kidney diseases.
4. What happens after using Mifepristone + Misoprostol?
Uterine bleeding will start after 1-2 days of taking the combination. This bleeding is not related to the success of the method. If pregnancy is not entirely removed. Surgical methods will be used to terminate the pregnancy completely. It is essential to take care of not becoming pregnant soon after the termination of pregnancy.
5. Does Mifepristone + Misoprostol affect your fertility?
You can become pregnant soon after the termination of the pregnancy. It is recommended to avoid pregnancy before the next menstrual period, and the use of the contraception method is recommended.
Mifepristone + Misoprostol in other salts
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