Nandrolone
Uses of Nandrolone
Nandrolone is primarily used for managing conditions such as anaemia, cachexia (wasting syndrome), osteoporosis, and certain types of breast cancer. It belongs to the group of synthetic anabolic-androgenic steroids (AAS).
Additionally, it has been used off-label for conditions like hereditary angioedema (which causes episodes of swelling) and to manage anaemia associated with chronic kidney failure.
Side effects of Nandrolone
Headaches
Diarrhoea
Nausea and vomiting
Stomach pain
Symptoms of masculinisation like acne and increased hair growth
How Nandrolone works
Nandrolone is an anabolic-androgenic steroid (AAS) medication.
It works by being an agonist of the androgen receptor, which means it binds to these receptors and activates them. These are the same receptors that are targeted by androgens like testosterone and dihydrotestosterone (DHT). This stimulates protein synthesis and encourages muscle growth. It also stimulates appetite and bone growth. It also has a strong anabolic effect, meaning it promotes tissue growth.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Nandrolone is available for use via an intra-muscular route (injection).
Age and Dose Restrictions
This medicine is primarily meant for adults.
Contraindications
This medicine is contraindicated in patients with known allergies to Nandrolone.
It is also contraindicated in patients with prostate cancer, carcinoma of the breast in females, pregnancy and severe kidney damage.
Other Medications to Avoid With This Medicine
Nandrolone may interact with other erythropoiesis-stimulating agents (ESAs) (Erythropoietin), anticoagulants ( warfarin and aspirin), and diabetes medications ( insulin, glipizide, and glimepiride).
Overdose and Missed Dose
An overdose of this medication may result in symptoms such as gastrointestinal discomfort like nausea, abdominal pain, and diarrhoea. More severe symptoms can include jaundice, liver damage, and kidney impairment or failure. In such scenarios, inform your doctor immediately.
If you miss a scheduled dose of this medication, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not double up on doses.
Management of Side Effects
Most side effects are temporary, generally harmless, and resolve upon stopping this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drink plenty of fluids and increase your fibre intake to manage symptoms like constipation.
If you have an upset stomach or nausea, try taking this medicine with food or a small snack.
Use in Driving and Operating Machinery
Nandrolone is unlikey to influence machines using and driving. Still, it is advised to avoid driving or operating heavy machinery if you experience these side effects after administering the medication.
Use in Pregnancy and Lactation
The use of Nandrolone is not recommended during pregnancy, as it may harm the foetus.
It is also not recommended for breastfeeding mothers, as Nandrolone is passed into breast milk.
Caution in Other Conditions
Patients with pre-existing liver or kidney disease/insufficiency, cardiac disease, epilepsy, mellitus diabetes or migraine should exercise caution when taking Nandrolone.
Special Dietary and Lifestyle Recommendation
Regular light exercises like walking or stretching can help maintain muscle mass and bone strength.
Regularly monitor blood glucose levels if you are a patient with diabetes, as Nandrolone can interact with insulin and oral diabetes medications.
Frequently asked questions
Can Nandrolone cause mood changes?
Yes, as with other anabolic-androgenic steroids, Nandrolone can cause mood changes like mood swings, anxiety, irritability, and depression.
Is there any natural alternative to Nandrolone?
No known natural alternative provides the same effects as this medicine.
Can I take Nandrolone if I am allergic to other steroids?
If you have a history of allergic reactions to other steroid medicines, it is advisable not to take this medicine without consulting your doctor first.
Can Nandrolone affect menstrual cycles in women?
Yes, it can have an impact on the menstrual cycle in women, causing irregularities or cessation of periods.
Does Nandrolone have any effect on appetite?
Yes, one of the effects of Nandrolone is the stimulation of appetite.
Is there any specific test required before starting Nandrolone?
Your doctor may recommend certain tests before starting you on this medicine to ensure it is safe for you. These may include liver function tests or hormone level checks.
How does Nandrolone affect hormone levels in the body?
This medicine is an anabolic steroid and it can impact the body's hormonal balance by suppressing natural testosterone production. This could lead to hormonal imbalances if not monitored.
Nandrolone in other salts
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