Naphazoline + Phenylephrine
Uses of Naphazoline + Phenylephrine
Naphazoline + Phenylephrine primarily provides relief from redness, puffiness, itching and watering of the eyes due to minor eye irritations, and falls under the category of decongestant medications.
This combination is also used to alleviate discomfort and minor irritation in the eyes caused by factors such as dust, smoke, smog, pollen, ragweed, grass, animal hair and dander, swimming, wearing contact lenses, common cold, hay fever or other upper respiratory allergies.
Side effects of Naphazoline + Phenylephrine
Temporary burning or stinging of the eye
Increased redness of the eye
Blurred vision
Headache or dizziness
Nervousness or drowsiness
How Naphazoline + Phenylephrine works
Naphazoline + Phenylephrine is a combination of two decongestant medications.
Naphazoline works by acting on the alpha receptors in the eyes, specifically in the conjunctival blood vessels. This causes them to constrict, which reduces redness and relieves minor eye irritation.
Phenylephrine also acts on the alpha receptors within the eye, causing vasoconstriction or narrowing of blood vessels. Additionally, it contracts the dilator muscle of the pupil, causing dilation of the pupil (mydriasis).
Certified content
Written By
MSc (Applied Genetics)
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Naphazoline + Phenylephrine is available in the form of a sterile ophthalmic solution for use via the topical route, to be applied directly to the eyes.
Age and Dose Restrictions
This medicine is designed for use by adults and children who are 6 years of age or older.
Contraindications
Naphazoline + Phenylephrine is contraindicated in patients with narrow-angle glaucoma or known hypersensitivity or allergy to any of the ingredients in this medication.
Other Medications to Avoid
This combination may interact with monoamine oxidase inhibitors (such as selegiline, isocarboxazid), tricyclic antidepressants (like amitriptyline, nortriptyline), beta-blockers (including atenolol, propranolol), anti-hypertensives (such as amlodipine, lisinopril), and cardiac glycosides (such as digoxin).
Overdose and Missed Dose
An overdose of Naphazoline + Phenylephrine can cause symptoms such as extreme drowsiness, sweating, decreased body temperature, slow heartbeat, and coma. In case of suspected overdose, seek immediate medical help.
If you miss a dose of this medicine, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Try to take the medicine at a time when you can rest and recover from the side effects, such as before bedtime.
Drink plenty of fluids to help ease the side effects and keep your body hydrated.
Use in Driving and Operating Machinery
Naphazoline + Phenylephrine may cause CNS depression, including drowsiness or dizziness. As such, it is advisable to avoid driving or operating heavy machinery while using this medication.
Use in Pregnancy and Lactation
This combination should be used only if prescribed by a doctor during pregnancy
Nursing mothers should use this medication only after medical consultation.
Caution in Other Conditions
Naphazoline + Phenylephrine should be used with caution in patients with heart disease, high blood pressure, diabetes or hyperthyroidism due to the potential for increased cardiovascular toxicity.
Special Dietary and Lifestyle Recommendations
Maintain clean eyes by avoiding touching them with dirty hands or exposing them to dust and irritants.
Regularly clean your contact lenses as per the manufacturer's instructions.
Try to avoid exposure to allergens known to trigger your symptoms such as dust, pollen, animal hair and dander.
Practice good eye hygiene by washing your eyes with clean water regularly.
If you are prone to allergies, wearing protective eyewear outdoors could help reduce eye irritation.
Frequently asked questions
Is Naphazoline + Phenylephrine a steroid?
No, Naphazoline + Phenylephrine is not a steroid. It consists of two decongestant medications known for their efficacy in relieving minor eye irritations.
Can Naphazoline + Phenylephrine affect my mood?
Although Naphazoline + Phenylephrine is primarily used for eye relief, it can potentially cause central nervous system depression, which may result in drowsiness or nervousness.
Can I use Naphazoline + Phenylephrine during menstruation?
There is no specific contraindication for using Naphazoline + Phenylephrine during menstruation. However, if you experience any discomfort or unusual side effects, consult your doctor.
Is Naphazoline + Phenylephrine a vegan product?
There is no clear information about the vegan status of Naphazoline + Phenylephrine. It is recommended to check the product packaging or consult your doctor or pharmacist for detailed information.
Is there a risk of addiction with Naphazoline + Phenylephrine?
Naphazoline + Phenylephrine is not known to cause addiction or dependence. However, prolonged use may lead to rebound congestion or chronic eye redness.
What happens if I stop using Naphazoline + Phenylephrine suddenly?
As Naphazoline + Phenylephrine is not an addictive substance, stopping its use suddenly should not trigger withdrawal symptoms. Nevertheless, always consult your doctor before making changes to your medication regimen.
Can I use Naphazoline + Phenylephrine if I have high blood pressure?
Naphazoline + Phenylephrine should be used with caution in patients with high blood pressure. Although it is primarily used for eye conditions, it can potentially impact blood pressure levels.
Naphazoline + Phenylephrine in other salts
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