Nimesulide + Serratiopeptidase

Dosage Forms Available

• Nimesulide + Serratiopeptidase is available in the form of tablets and capsules for oral consumption.

Age and Dose Restrictions

• This combination therapy is intended for adults and children over the age of 12. It is not recommended for use in children under 12 years of age due to safety and efficacy concerns.

Contraindications

• Nimesulide + Serratiopeptidase is contraindicated in individuals who are allergic to either nimesulide or serratiopeptidase, or any other ingredients present in the formulation.

• It is also contraindicated in patients with severe liver, kidney, or heart failure and those with active gastrointestinal ulcers.

Other Medications to Avoid

• The Nimesulide + Serratiopeptidase combination can interact with anticoagulants (e.g., warfarin and edoxaban), antiplatelet medications (e.g., clopidogrel and cilostazol), other NSAIDs (e.g., ibuprofen and etoricoxib), ACE inhibitors (e.g., lisinopril and quinapril), diuretics (e.g., furosemide and torsemide), lithium-containing medications, methotrexate, corticosteroids (e.g., prednisone and triamcinolone), and selective serotonin reuptake inhibitors (SSRIs) (e.g., fluoxetine and citalopram).

Overdose and Missed Dose

• An overdose of Nimesulide + Serratiopeptidase may lead to severe gastrointestinal bleeding, kidney damage, or liver damage. If you suspect an overdose, contact your doctor immediately.

• If you miss a dose of this medication, take it as soon as you remember. However, if it is near the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and typically resolve once the medication is discontinued.

• To manage nausea, take this medication with or after meals.

• If you experience stomach discomfort, taking an antacid recommended by your doctor may help.

• Drinking plenty of fluids can help prevent dehydration, which can occur due to adverse effects like vomiting or diarrhoea.

Use in Driving and Operating Machinery

• Nimesulide + Serratiopeptidase can cause dizziness or sleepiness in some individuals. If you experience these side effects, it is advised to avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

• Nimesulide + Serratiopeptidase is not recommended during pregnancy or while breastfeeding unless deemed essential by your doctor. Always consult your doctor before taking this medication if you are pregnant or breastfeeding.

Caution in Other Conditions

• Patients with a history of gastrointestinal ulcers, liver disease, kidney disease, heart disease, or high blood pressure should exercise caution while taking Nimesulide + Serratiopeptidase.

Special Dietary and Lifestyle Recommendations

• Maintain a balanced diet rich in fruits, vegetables, and lean proteins to promote overall health.

• Limit intake of foods high in sodium, as it can worsen swelling and inflammation.

• Regular, moderate physical activity can help manage pain and improve joint flexibility. However, avoid strenuous activities that could exacerbate your condition.

• Adequate rest and sleep are essential for recovery and healing.

• Avoid smoking and limit alcohol consumption, as they can increase the risk of gastrointestinal bleeding.