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Norfloxacin

Uses of Norfloxacin

  • The main use of Norfloxacin is to manage bacterial infections, specifically those of the urinary tract, gastrointestinal tract, and gonorrhoea. It belongs to a class of medications known as fluoroquinolones.

  • Secondary uses of Norfloxacin include managing prostatitis and travellers' diarrhoea, when these conditions are caused by susceptible bacterial strains.

Side effects of Norfloxacin

  • Nausea

  • Diarrhoea

  • Headache

  • Rash

  • Dizziness

How Norfloxacin works

  • Norfloxacin is part of the fluoroquinolone class of antibiotics.

  • It inhibits two important bacterial enzymes, DNA gyrase and topoisomerase IV. These enzymes are crucial for the process of bacterial DNA replication and repair, which means they are essential for the bacteria's survival and multiplication.

Certified content

Written By

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Dr Vatsalya D GhanekarMedical Content Writer| 5 years

MD Ayurveda

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Norfloxacin can be taken orally (tablets and oral suspension).

  • It is also available in injectable form for both intravenous and intramuscular administration.

Age and Dose Restrictions

  • Norfloxacin is intended for use in adults.

Contraindications

  • Norfloxacin is contraindicated in individuals with known allergies to the medication or other quinolones. It should not be administered to those with a history of tendon disorders related to quinolone use.

Other Medications to Avoid

  • Norfloxacin may interact with antigout agents (such as probenecid and colchicine), antacids (such as aluminium hydroxide), iron salts (like ferrous sulfate), zinc salts (such as zinc acetate) antiarrhythmic medicines (like amiodarone and sotalol), certain antibiotics (like erythromycin) and certain antipsychotics (like haloperidol).

Overdose and Missed Dose

  • If you suspect an overdose of Norfloxacin, contact your doctor immediately. Symptoms may include gastrointestinal discomfort and central nervous system disturbances.

  • If you miss a dose, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary, generally harmless, and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.

  • To manage nausea or an upset stomach that might occur with this medication, try taking it with food.

  • Drinking plenty of fluids may help to alleviate headaches.

Use in Driving and Operating Machinery

  • Norfloxacin may cause dizziness and affect your ability to drive or operate heavy machinery. If you feel dizzy or unsteady, avoid these activities.

Use in Pregnancy and Lactation

  • Norfloxacin is not recommended for use during pregnancy or lactation unless specifically advised by your doctor. Always consult your doctor before taking this medicine during pregnancy or while breastfeeding.

Caution in Other Conditions

  • Patients with liver issues, kidney problems or a history of seizures should exercise caution when taking Norfloxacin, as dosage adjustment may be needed.

Special Dietary and Lifestyle Recommendations

  • Maintain a good hydration level by drinking plenty of fluids while taking this medication, especially if you are experiencing diarrhoea.

  • To prevent urinary tract infections, aim to urinate regularly and empty your bladder each time.

  • Practise safe sex to prevent sexually transmitted diseases, such as gonorrhoea, for which Norfloxacin is often used.

Frequently asked questions

Norfloxacin has been linked to central nervous system effects such as anxiety and confusion, which can indirectly affect a person's mood. However, these side effects are quite rare.

There are reports of Norfloxacin causing insomnia or difficulty sleeping in some patients. If you experience such issues, you should consult your doctor.

Norfloxacin is not directly associated with affecting menstrual cycle disruptions. If you notice any changes in your menstrual cycle while taking this medicine, it is advised to consult your doctor.

Norfloxacin is an antibiotic, and there are no natural alternatives that have the same effectiveness against bacterial infections. Always consult your doctor before trying any alternatives or home remedies.

Yes, allergic reactions to Norfloxacin are possible, though rare. Symptoms can include rash, itching, swelling, severe dizziness and trouble breathing.

Rarely, norfloxacin may cause tendinitis and tendon rupture, especially in elderly patients over 60 years, those on corticosteroid therapy, and people with kidney, heart or lung transplants. Immediate discontinuation is required if tendon pain, inflammation or rupture occurs.

While loss of appetite is not a common side effect of Norfloxacin, it can occasionally occur due to gastrointestinal side effects such as nausea or abdominal pain.

Terms & Conditions


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