Noxitef 400 Mg Tablet 10

Noxitef Tablet 10

Leeford Healthcare

Strip of 10 Units

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MRP ~~₹52.5~~

₹26.25

₹5.25/Units

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Composition

Norfloxacin (400 Mg)

Noxitef Tablet 10 is primarily used to manage urinary tract infections (UTIs). It is an antibiotic medication, specifically a fluoroquinolone antibiotic.

In addition to managing UTIs, Noxitef Tablet 10 is also used to manage gonococcal urethritis and cervicitis, prostatitis, and select gastrointestinal infections, such as travellers' diarrhoea.

Consulting your doctor is crucial in determining your correct dosage and frequency. Always inform your doctor about any pre-existing conditions or current medications you are on before starting this medicine. Should you experience any side effects, contact your doctor right away. Continue taking the medicine for the prescribed duration for optimal results.

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Noxitef Tablet 10 is used for managing the following health conditions:

Urinary tract infections involving the kidneys, bladder, ureters or urethra
Gonococcal urethritis and cervicitis caused by a type of bacteria called Neisseria gonorrhoeae
Prostatitis, which is the inflammation of the prostate gland
Certain types of gastrointestinal infections like travellers' diarrhoea

Here are the instructions you need to follow while taking Noxitef Tablet 10:

Swallow the tablet whole with a glass of water.
Take this medicine on an empty stomach, either 1 hour before or 2 hours after meals.
Do not break, crush or chew the tablet.
You must complete the entire course as your doctor advises, even if symptoms improve.
Always consult your doctor before adjusting your dosage or stopping this medicine.

Noxitef Tablet 10 is taken orally.

Noxitef Tablet 10 may have the following common side effects:

Nausea
Abdominal pain
Diarrhoea
Headache
Dizziness
Skin rash or itching

Managing the Side Effects:

Most side effects are temporary and generally harmless, and they resolve when you discontinue using Noxitef Tablet 10. However, if you experience serious side effects or worsening symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Noxitef Tablet 10 with food to lessen this effect.
Abdominal pain: Consider taking this medicine after meals to help manage this symptom.

Noxitef Tablet 10 contains Norfloxacin (400 mg), which interacts with your body in the following ways:

Inhibition of Bacterial Enzymes: Norfloxacin works by inhibiting two essential bacterial enzymes - DNA gyrase and topoisomerase IV.
Prevention of Bacterial Replication: By halting the action of these enzymes, Norfloxacin prevents bacteria from replicating, repairing, and transcribing their DNA.
Broad-Spectrum Antibacterial Activity: This mechanism gives Norfloxacin a broad-spectrum antibacterial activity against Gram-positive and Gram-negative bacteria, helping manage various bacterial infections effectively.

Pregnancy

Caution is advised while taking Noxitef Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it's crucial to discuss the potential risks and benefits with your doctor before starting Noxitef Tablet 10.

Alcohol

Consuming alcohol while taking Noxitef Tablet 10 can increase the risk of dizziness, drowsiness, and lightheadedness, making it unsafe to engage in activities requiring alertness. Additionally, alcohol may exacerbate potential gastrointestinal side effects like nausea or stomach upset.

Liver

If you have mild to moderate liver impairment, caution is advised while taking Noxitef Tablet 10. This medicine is not recommended for severe liver diseases. Discuss any liver problems with your doctor before starting this medicine, as it may affect liver function.

Kidney

If you have a history of kidney problems, it's a good idea to consult your doctor before taking Noxitef Tablet 10.

Using Machines & Driving

Noxitef Tablet 10 may cause dizziness or headache. If you experience these side effects, avoid driving or operating heavy machinery until the symptoms subside.

Allergy

Noxitef Tablet 10 is contraindicated in patients with a known allergy to norfloxacin or other quinolone antibiotics. Always inform your doctor about any allergies before starting this medication.

Children

Safety and efficacy in children have not been established for Noxitef Tablet 10. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Noxitef Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age as they might also have liver and kidney issues and might be on other medications. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Noxitef Tablet 10 interacts with the following medicines:

Antacids, iron or zinc supplements: These may hinder the absorption of Noxitef Tablet 10, affecting its efficacy. Examples include aluminium hydroxide and ferrous sulphate.
Anticoagulants: Medicines such as warfarin may interact with Noxitef Tablet 10, potentially increasing the risk of bleeding.
Medicines for diabetes: They may interact with this medication, leading to altered medicine effects. Examples include metformin.

Drug-Food Interactions

Certain food items can interfere with the effectiveness of Noxitef Tablet 10:

Dairy products: Consuming dairy products around the same time as taking Noxitef Tablet 10 could reduce its absorption in the body, decreasing its effectiveness.

Drug-Disease Interactions

Noxitef Tablet 10 interacts with the following diseases:

Kidney Disease: Patients with kidney disease may need dose adjustments of Noxitef Tablet 10 due to decreased renal function.
Seizures: Individuals with a history of seizures could experience an increase in seizure frequency when taking this medicine.
Myasthenia Gravis: This medicine can worsen muscle weakness in people suffering from myasthenia gravis.

Daily Dose

Your doctor will determine the daily dose of Noxitef Tablet 10, considering factors like the severity of your condition and your response to the medication. Following the prescribed dosage without exceeding is crucial unless your doctor advises otherwise.

Over Dose

If you accidentally take more Noxitef Tablet 10 than prescribed, you may experience symptoms like nausea or headaches. It's important to inform your doctor if such situations arise or if these symptoms persist.

Missed Dose

If you forget to take Noxitef Tablet 10 at the scheduled time, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed one and continue with your regular schedule. Always consult your doctor before making any changes to your dosage.

Store Noxitef Tablet 10 in a cool place, ideally below 30°C.
Keep it away from direct sunlight and moisture.
Ensure it's out of reach of children and pets.
Always check the expiry date before use, and do not use it if expired.

Increase your water intake for urinary tract infections managed by Noxitef Tablet 10. This helps flush out bacteria and accelerates recovery.
If you're dealing with gastrointestinal infections like travellers' diarrhoea, maintain a light diet rich in probiotics, such as yoghurt, which can help restore gut health.

Fact Box

Drug Category	DNA Synthesis Inhibitor
Therapeutic Category	Fluoroquinolone Antibiotic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Urinary Tract Infections, Gonococcal Urethritis, Travellers' Diarrhoea

What is Noxitef Tablet 10 used for?

Noxitef Tablet 10 is primarily used to manage bacterial infections such as urinary tract infections, gonococcal urethritis and cervicitis, prostatitis, and certain gastrointestinal infections.

How does Noxitef Tablet 10 work?

This medicine works by inhibiting key bacterial enzymes, disrupting the bacteria's ability to replicate and repair their DNA, and thus effectively managing the infection.

What are the common side effects of Noxitef Tablet 10?

Common side effects can include nausea, abdominal pain, diarrhoea, headaches, dizziness, and sometimes skin rash or itching.

Can Noxitef Tablet 10 be taken on an empty stomach?

Yes, it's recommended to take this medicine on an empty stomach either one hour before or two hours after meals to enhance absorption.

When should I stop taking Noxitef Tablet 10?

You should not stop taking the medicine until you have completed the entire course as prescribed by your doctor, regardless of symptom improvement.

Can I take Noxitef Tablet 10 if I am pregnant or breastfeeding?

Consult your doctor before taking this medicine if you are pregnant or breastfeeding since it may not be safe to use in these situations.

Can Noxitef Tablet 10 interact with other medicines?

Yes, it may interact with specific medications, such as antacids, blood thinners, and certain other medicines. Always inform your doctor about all the medicines you're currently taking.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Leo House, Shaheed Bhagat Singh Nagar, Dugri Dhandra Road, Near Joseph School Ludhiana PB 141002 IN

Country of origin: INDIA

References

FDA. (n.d.). NOROXIN (NORFLOXACIN). https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019384s062lbl.pdf
Food and Drug Administration. (2011). Supplement approval for NOROXIN tablets. https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2011/019384s056ltr.pdf
Arrow. (1 C.E.). Arrow – Norfloxacin. https://medsafe.govt.nz/profs/Datasheet/a/ArrowNorfloxacintab.pdf
Summary of product characteristics. (2021). http://www.efda.gov.et/wp-content/uploads/2023/08/Norfloxacin_Norfloxacin-Tablets_medicamen-Biotech-Ltd.pdf
Norfloxacin: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01059
PubChem. (n.d.). Norfloxacin. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Norfloxacin

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