Nortriptyline

Dosage Forms Available

• Nortriptyline can be taken orally (capsules and solution).

Age and Dose Restrictions

• This medication is prescribed for adults and children above the age of 6 years.

Contraindications

• This medicine is contraindicated in patients with hypersensitivity to Nortriptyline or any other tricyclic antidepressants. It is also contraindicated in patients with recent myocardial infarction, heart block, severe cardiovascular disorders, and those undergoing concurrent MAO inhibitor therapy.

Other Medications to Avoid

• Nortriptyline may interact with MAO inhibitors (such as selegiline, isocarboxazid), SSRIs (such as escitalopram, fluoxetine), SNRIs (such as venlafaxine, duloxetine), CYP2D6 inhibitors (like fluoxetine, quinidine) and sympathomimetics (like phenylephrine, epinephrine).

Overdose and Missed Dose

• An overdose of Nortriptyline can cause symptoms like irregular heartbeat, severe drowsiness and seizures. Immediate medical attention should be sought in such cases.

• If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage dry mouth caused by this medication.

• If you experience constipation, increase your fibre intake by consuming fruits, vegetables and whole grains.

Use in Driving and Operating Machinery

• Nortriptyline may cause drowsiness or dizziness. Avoid driving or operating heavy machinery if you experience these side effects.

Use in Pregnancy and Lactation

• Nortriptyline should only be used during pregnancy and lactation if the benefits outweigh the potential risks. It is advised to consult your doctor before using this medicine during pregnancy and lactation.

Caution in Other Conditions

• Patients with a history of seizures, cardiovascular disease, glaucoma, or liver disease should exercise caution when taking Nortriptyline.

Special Dietary and Lifestyle Recommendations

• Mind-body practices like yoga, meditation, and deep breathing exercises can help manage stress and improve mood.

• It's advisable to maintain a regular sleep schedule to manage symptoms of depression effectively.