Ondansetron + Pantoprazole

Dosage Forms Available

• Ondansetron + Pantoprazole is available for oral consumption as a tablet.

Age and Dose Restrictions

• This combination is intended for use by adults 18 years of age and older.

Contraindications

• This combination is contraindicated in patients with known allergies to either component.

• It is also contraindicated for patients with severe liver impairment.

Other Medications to Avoid

• This combination may interact with antidepressants (such as duloxetine, escitalopram), diuretics (such as furosemide), blood thinners (such as clopidogrel), antibiotics (such as clarithromycin, metronidazole), anti-fungal medications (such as ketoconazole), and HIV medications (such as atazanavir, nelfinavir).

Overdose and Missed Dose

• An overdose of this combination may result in excessive dryness of the mouth, confusion, blurred vision, severe dizziness or fainting. If you suspect an overdose, it is important to seek medical attention immediately.

• If you miss a dose, take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take an extra dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage nausea, take the medication with or after food.

• If experiencing mild headaches or dizziness, ensure adequate hydration by drinking plenty of water.

Use in Driving and Operating Machinery

• This combination can sometimes cause dizziness or blurred vision. It may affect your ability to drive or operate heavy machinery. Avoid these activities if you experience these side effects.

Use in Pregnancy and Lactation

• The safety of using Ondansetron + Pantoprazole during pregnancy and lactation has not been fully established. It is advised to consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

• Those with a history of cardiac conditions such as arrhythmias should be cautious due to the potential QT prolongation effect of Ondansetron.

Special Dietary and Lifestyle Recommendations

• Avoid foods that trigger heartburn, such as spicy foods, chocolate, caffeine, and fatty foods.

• Eat smaller, more frequent meals instead of three large meals a day.

• Do not lie down immediately after eating; wait at least three hours.

• Elevate the head of your bed to help prevent stomach acid from flowing back into the oesophagus while sleeping.