Phenylephrine + Tropicamide
Uses of Phenylephrine + Tropicamide
Phenylephrine + Tropicamide is primarily used in ophthalmology for diagnostic procedures and short-term therapeutic purposes. It belongs to the group of ophthalmic diagnostic agents.
It is indicated for dilating the pupil (mydriasis) for diagnostic eye examinations, inducing short-acting mydriasis in pre-and post-operative states, and relaxing the ciliary muscle (cycloplegia) for diagnostic procedures.
Side effects of Phenylephrine + Tropicamide
Stinging or burning sensation in the eye
Increased sensitivity to light (photophobia)
Blurred vision
Dry mouth
Rapid heartbeat (tachycardia)
How Phenylephrine + Tropicamide works
Phenylephrine + Tropicamide is a combination medicine used in ophthalmic applications.
Phenylephrine is a decongestant that works by reducing swelling of blood vessels. This substance affects the α1-adrenergic receptor in the eye, causing the dilator muscle of the pupil to contract and thus widen or dilate the pupil (mydriasis).
Tropicamide is an anticholinergic agent that blocks acetylcholine, a neurotransmitter, at muscarinic receptors in the eye. It relaxes the sphincter muscle of the iris and the ciliary muscle, also contributing to the dilation of the pupil and temporary paralysis of the ciliary muscle (cycloplegia).
Certified content
Written By
MD Ayurveda
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Phenylephrine + Tropicamide is available in the form of eye drops.
Age and Dose Restrictions
This medicine can be used by adults and children aged 6 years and above. A doctor should determine the dose and duration of use of this medicine.
Contraindications
This medicine is contraindicated in patients with known hypersensitivity to any component of the formulation.
It is also contraindicated in patients with narrow-angle glaucoma.
Other Medications to Avoid
Phenylephrine + Tropicamide may interact with monoamine oxidase inhibitors (selegiline and isocarboxazid), tricyclic antidepressants (amitriptyline and clomipramine), and other sympathomimetic agents (ephedrine and pseudoephedrine).
This combination may also interact with alpha-blockers (such as tamsulosin and doxazosin) and beta-blockers (such as propranolol and metoprolol).
Overdose and Missed Dose
In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.
If you miss a dose of this medicine, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and return to your regular dosing schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage burning or stinging sensation in the eye after using this medicine, one can try blinking rapidly or closing the eyes for a few minutes.
To manage increased sensitivity to light, try wearing sunglasses or staying in a dim environment until the effects of the medicine subside.
For managing a dry mouth, drinking water frequently or chewing sugar-free gum may help.
Use in Driving and Operating Machinery
Phenylephrine + Tropicamide may cause temporary blurred vision. Therefore, driving or operating heavy machinery should be avoided until the vision is clear.
Use in Pregnancy and Lactation
Consult your doctor before using Phenylephrine + Tropicamide during pregnancy and breastfeeding. The safety of this medicine in these conditions is not well established.
Caution in Other Conditions
Patients with hypertension, hyperthyroidism, or cardiovascular disease should exercise caution when using Phenylephrine + Tropicamide.
Also, patients with narrow anterior chamber angles or those with a history of allergic reactions to either component should use this medicine cautiously under the doctor's supervision.
Special Dietary and Lifestyle Recommendations
Maintain regular eye check-ups to monitor the health of your eyes, especially if you frequently use eye drops.
Ensure a balanced diet rich in vitamin A and omega-3 fatty acids for overall eye health.
Rest your eyes often when performing tasks that require visual concentration, such as reading or working on a computer.
Protect your eyes from excessive light or UV radiation by wearing sunglasses.
Frequently asked questions
Can Phenylephrine + Tropicamide affect vision?
Yes, one of the side effects of Phenylephrine + Tropicamide is blurred vision. Following administration, patients may temporarily experience difficulty focusing on close objects. It is advised to avoid tasks requiring clear vision, such as reading or operating machinery, until the effects have subsided.
Is a prescription required for purchasing Phenylephrine + Tropicamide?
Yes, a prescription from a registered medical practitioner is required to purchase Phenylephrine + Tropicamide.
Can Phenylephrine + Tropicamide cause dry mouth?
Yes, one of the common side effects of Phenylephrine + Tropicamide is dry mouth. It is important to stay hydrated while using this medicine.
How does Phenylephrine + Tropicamide affect my heartbeat?
Phenylephrine + Tropicamide can lead to tachycardia, which is a rapid heartbeat. You should consult your doctor if you have any heart-related conditions before using this medicine.
Are there any alternatives to Phenylephrine + Tropicamide?
There may be other medicine combinations available that can act in a similar way as Phenylephrine + Tropicamide. Please consult your doctor for advice on alternatives.
Can I wear contact lenses while using Phenylephrine + Tropicamide?
The solution should not come into contact with soft contact lenses due to the risk of discolouration. Therefore, it's recommended to remove your contact lenses before application.
Do I need a prescription to buy Phenylephrine + Tropicamide?
Yes, a prescription from a registered medical practitioner is typically required to acquire Phenylephrine + Tropicamide.
Phenylephrine + Tropicamide in other salts
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