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Polyethylene Glycol

Uses of Polyethylene Glycol

  • Polyethylene Glycol's main use is as an osmotic laxative for the management of occasional constipation in adults and children and belongs to the group of laxative medicines.
  • In addition, it is also used for bowel preparation before colonoscopy, surgery, or other diagnostic procedures.

Side effects of Polyethylene Glycol

  • Nausea
  • Abdominal bloating
  • Cramping
  • Gas
  • Diarrhoea

How Polyethylene Glycol works

  • Polyethylene Glycol is an osmotic laxative.
  • When this medicine is taken, it does not get absorbed into the body but stays within the digestive tract. Here, it draws water from the body into the intestines, similar to a sponge absorbing water.
  • The increase in water content within the intestines softens the stool and increases its volume. These softer, bulkier stools stimulate the intestines to contract and push out the stool, aiding regular bowel movements.
  • Through this mechanism, Polyethylene Glycol effectively manages constipation and other bowel irregularities.

Certified content

Written By

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Ashmita BorgohainMedical Content Writer & Editor| 12 years

MSc (Applied Genetics)

Reviewed By

Dr. Meenakshi Maruwada
Dr. Meenakshi Maruwada Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Expert Advice

Dosage Forms Available

  • Polyethylene Glycol is available for use via oral route in the form of a powder for solution and ready-to-use solutions. The powder formulation is designed to be mixed with water or other beverages before consumption, whereas the ready-to-use solutions are pre-mixed and require no additional preparation.

Age and Dose Restrictions

  • This medicine is meant for adults and children above the age of 2 years. However, it should always be used under medical supervision.

Contraindications

  • Polyethylene Glycol is contraindicated in patients with known allergies to polyethylene glycol or any component of the formulation.
  • It is also contraindicated in patients with known or suspected gastrointestinal obstruction, perforation, or ileus.

Other Medications to Avoid

  • Polyethylene Glycol may interact with certain medications that affect bowel motility or are intended to treat constipation (such as loperamide).
  • Additionally, it may interact with medications that affect electrolyte balance (like diuretics). It is crucial to consult a doctor before starting any prescription or over-the-counter medications.

Overdose and Missed Dose

  • An overdose of Polyethylene Glycol may cause symptoms such as severe diarrhoea, nausea, or vomiting. In case of an overdose, immediately consult your doctor.
  • If you forget to take this medicine, take it as soon as you remember. However, if it's near the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up the doses.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of fluids can help manage dehydration or electrolyte imbalance.
  • Taking Polyethylene Glycol with food may help reduce gastrointestinal side effects like bloating or gas.

Use in Driving and Operating Machinery

  • Polyethylene Glycol does not typically affect your ability to drive or operate heavy machinery. However, avoid driving or operating machinery if you experience dizziness or lethargy after taking Polyethylene Glycol.

Use in Pregnancy and Lactation

  • Polyethylene Glycol is generally considered safe during pregnancy and breastfeeding. However, pregnant or nursing women should consult their doctor before starting the medication.

Caution in Other Conditions

  • Patients with kidney disease should use Polyethylene Glycol under medical supervision, as it may affect electrolyte balance and hydration status.
  • Patients with known or suspected bowel obstruction should also exercise caution while using Polyethylene Glycol.

Special Dietary and Lifestyle Recommendations

  • Drinking plenty of water throughout the day can help maintain your body's hydration status and promote regular bowel movements.
  • Consuming a balanced diet rich in fibre can help promote regular bowel movements and improve gut health.
  • Light physical activities like walking can stimulate the intestines and help manage constipation.

Frequently asked questions

Depending on the reason for use, there may be natural alternatives to Polyethylene Glycol. For constipation, increasing fibre intake, staying well-hydrated, and regular physical activity can help promote bowel regularity. However, it is always best to consult a doctor before starting any natural alternatives.

Polyethylene Glycol is a synthetic compound and does not contain any animal-derived ingredients, making it acceptable for people following vegetarian or vegan diets. However, always check with the manufacturer or your pharmacist, as other ingredients in the formulation may not be suitable for vegetarians or vegans.

Polyethylene Glycol is generally considered safe for use during breastfeeding. Still, it is recommended that breastfeeding women consult their doctor before starting this medication.

Polyethylene Glycol does not typically affect mood or hormones; it primarily draws water into the intestines to promote bowel movements.

There are no specific food items that you need to avoid while taking Polyethylene Glycol. However, staying hydrated and maintaining a balanced diet can help manage potential side effects.

Polyethylene Glycol does not typically cause dependency or withdrawal symptoms. It is not absorbed into the body system but works in the gut lumen.

Yes, there are other osmotic laxatives similar to polyethylene glycol available, such as lactulose and magnesium hydroxide. However, always consult your doctor before switching or starting new medications.

Terms & Conditions


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