Home/Drugs By Ailments / Prednisolone

Prednisolone

STEROID

Uses of Prednisolone

  • Prednisolone is used to treat a variety of conditions, including allergies, inflammation, blood disorders, skin diseases, eye diseases, respiratory issues, certain cancers, and endocrine problems.
  • It is also used to prevent organ rejection after a transplant and manage swelling and intestinal disorders.

Side effects of Prednisolone

  • Headache
  • Nausea
  • Acne
  • Increased appetite
  • Difficulty in falling asleep
  • Slow healing of cuts and wounds 
  • Increased sweating 

How Prednisolone works

  • Prednisolone belongs to the class of medications called corticosteroids
  • It mimics the cortisol secreted by the adrenal gland, which is responsible for stress and metabolism.
  • Low doses of prednisolone have anti-inflammatory effects, while high doses have an immunosuppressive effect. It binds to the glucocorticoid receptor and mediates the gene expression, which is responsible for decreased vasodilation, increased capillary permeability, reduced leukocyte migration to the inflammation site, promotes anti-inflammatory signals, and inhibits pro-inflammatory signals. 

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Prednisolone can be taken orally (tablet and solution).

Age And Dose Restrictions

  • It is intended to be used by adults and children only when prescribed by a doctor. 

Contraindications 

  • It is contraindicated in patients with a history of hypersensitivity to Prednisolone, children having history of exposure to chickenpox, measles, or shingles, patients having worm infestation, severe depression, diabetes, glaucoma, fungal eye infection, hypertension, pancreatitis, peritonitis, scleroderma, myasthenia gravis, osteoporosis, pheochromocytoma, or thrombophlebitis.

Other Medications To Avoid With This Medicine

  • Avoid taking medicines that are used to treat glaucoma and epilepsy (acetazolamide), anticoagulants (warfarin), cardiac medications (digoxin), oral contraceptives (ethinylestradiol), antifungals (ketoconazole), anti-tuberculous agents (rifampicin), antiviral medications (ritonavir), NSAIDs (aspirin), neuromuscular blocking agents (pancuronium), diuretics (hydrochlorothiazide) and immunosuppressants (tacrolimus) with Prednisolone. These medications may alter the safety and effectiveness of Prednisolone.

Overdose And Missed Dose

  • If you take an overdose of this medication by accident and experience any severe side effects or worsening of any of the symptoms, please consult your doctor. Strict adherence to the prescribed dose is essential.
  • If you miss a dose of Prednisolone, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management Of Side Effects

  • The side effects are resolved after discontinuing this medication. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • Refrain from driving or operating machinery after using this medication, as it may cause dizziness.

Use In Pregnancy And Lactation

  • Prednisolone is not recommended during pregnancy and breastfeeding.

Caution In Other Conditions

  • Caution is advised in older adults and patients with kidney and liver impairment.

Special Dietary And Lifestyle Recommendation

  • Monitor your weight by monitoring your calorie intake and regular physical activity.
  • Manage stress levels by finding healthy coping methods, such as spending time with loved ones and practising mindfulness methods like meditation and deep breathing.
  • Monitor your salt intake and limit high-sodium foods to help maintain healthy blood pressure levels.
  • Consider limiting or avoiding alcohol consumption, as excessive alcohol intake can adversely affect heart health.
  • Quitting smoking is a practical way to reduce the risk of heart disease, so if you smoke, seek support to quit.

Frequently asked questions

Yes, it is a steroid.

No, it is not recommended in pregnancy. 

No, it is not recommended for breastfeeding women.

It is better to take this tablet with food rather than without food to avoid stomach upset. 

Be cautious about the use of this medication in liver diseases. 

Be cautious about the use of this medication in kidney diseases. 

Terms & Conditions


Available medicines for PREDNISOLONE
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Omnacortil 5 Tablet 10
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