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Saxagliptin

Uses of Saxagliptin

  • Saxagliptin is primarily used for managing type 2 diabetes mellitus and belongs to the group of medicines known as dipeptidyl peptidase-4 (DPP-4) inhibitors.

Side effects of Saxagliptin

  • Upper respiratory tract infection

  • Urinary tract infection

  • Headache

  • Diarrhoea

  • Hypoglycaemia

How Saxagliptin works

  • Saxagliptin is a Dipeptidyl Peptidase-4 (DPP-4) Inhibitor.

  • It works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4), which helps to increase levels of incretin hormones. These hormones enhance insulin secretion in response to meals and reduce glucose production in the liver, thereby lowering blood sugar levels.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Saxagliptin is available in tablet form for oral administration.

Age and Dose Restrictions

  • Saxagliptin is meant for use in adults and adolescents above 18 years of age.

Contraindications

  • Saxagliptin is contraindicated in patients with a history of hypersensitivity to any of its components.

  • It is also contraindicated in individuals with a history of pancreatitis.

Other Medications to Avoid

  • This medicine interacts with strong inhibitors of CYP3A4/5 enzymes, which may significantly increase saxagliptin exposure. These include antifungals (e.g., ketoconazole, itraconazole), antiretrovirals (e.g., atazanavir, ritonavir, nelfinavir), macrolide antibiotics (e.g., clarithromycin, telithromycin), and other medications (e.g., indinavir, nefazodone, saquinavir).

Overdose and Missed Dose

  • An overdose of Saxagliptin may lead to symptoms such as nausea, vomiting, and diarrhoea. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose of Saxagliptin, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For nausea or abdominal discomfort after taking Saxagliptin, try taking it with food or a glass of water.

  • If you experience dizziness after taking Saxagliptin, sit or lie down until the sensation passes.

Use in Driving and Operating Machinery

  • Saxagliptin may cause dizziness in some individuals. If you experience dizziness after taking this medicine, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • The safety of Saxagliptin in pregnancy and lactation has not been established. Consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Caution is advised when using Saxagliptin in patients with renal impairment or reduced kidney function. Dosage adjustments may be necessary based on kidney function.

  • Patients with a history of heart failure should also use Saxagliptin cautiously under medical supervision.

Special Dietary and Lifestyle Recommendations

  • Follow a balanced diet rich in whole grains, fruits, vegetables, and lean proteins to help manage blood sugar levels.

  • Monitor carbohydrate intake to avoid blood sugar spikes.

  • Engage in regular physical activity such as brisk walking, cycling, or swimming to improve insulin sensitivity.

  • Maintain a healthy weight to reduce the burden on your body's ability to use insulin effectively.

  • Avoid smoking and limit alcohol consumption as these can negatively impact blood sugar control and overall health.

Frequently asked questions

No, Saxagliptin is not a steroid. It belongs to the class of medicines known as dipeptidyl peptidase-4 (DPP-4) inhibitors, which are used to manage type 2 diabetes.

Saxagliptin does not usually impact sleep. However, each individual may react differently to the medicine. If you experience any issues with your sleep, consult your doctor.

Saxagliptin is not known to affect fertility. However, if you have concerns, it's best to consult with a doctor for personalized advice.

A balanced diet is recommended when taking Saxagliptin, especially one that assists in managing blood sugar levels. It is always advisable to consult your doctor for appropriate dietary advice based on your health condition.

Yes, it is generally safe to take Saxagliptin daily as prescribed by your doctor. The medicine should be taken exactly as directed and continued for as long as advised by your doctor.

Saxagliptin begins to work within a few hours of administration, helping to lower blood sugar levels effectively. However, it takes a few weeks of regular administration to observe its full benefits.

The duration of treatment with Saxagliptin varies based on the patient's condition and response to the medicine. It is usually prescribed as a long-term treatment for managing type 2 diabetes.

Terms & Conditions


Saxagliptin in other salts

Available medicines for SAXAGLIPTIN
Zaxaglit 5 Tablet 10
Zaxaglit 5 Tablet 10
Chemo Health Care Pvt Ltd
Pack of 10 Units
₹224.64
MRP ₹432.00
48.00% OFF
Saxaquest 2.5 Tablet 10
Saxaquest 2.5 Tablet 10
Morepen Laboratories Limited
Pack of 10 Units
₹96.06
MRP ₹192.50
50.10% OFF
Oxagliptin 2.5 MG Tablet 14
Oxagliptin 2.5 MG Tablet 14
Prevego Healthcare & Research Pvt.ltd.
Pack of 14 Units
₹272.45
MRP ₹546.00
50.10% OFF
Saxaquest 5 MG Tablet 10
Saxaquest 5 MG Tablet 10
Morepen Laboratories Limited
Pack of 10 Units
₹99.11
MRP ₹190.00
47.83% OFF
Riax 5 MG Tablet 14
Riax 5 MG Tablet 14
Dr. Reddys Laboratories Ltd
Pack of 14 Units
₹496.10
MRP ₹605.00
18.00% OFF
Glisaxapin Tablet 15
Glisaxapin Tablet 15
Steris Healthcare
Pack of 15 Units
₹142.22
MRP ₹285.00
50.10% OFF
Onglyza 2.5mg Tablet 14
Onglyza 2.5mg Tablet 14
Astrazeneca Pharma India Ltd
Pack of 14 Units
₹492.41
MRP ₹600.50
18.00% OFF
Onglyza 5mg Tablet 14
Onglyza 5mg Tablet 14
Astrazeneca Pharma India Ltd
Pack of 14 Units
₹545.71
MRP ₹665.50
18.00% OFF

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