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Sodium Carboxymethyl Cellulose

Uses of Sodium Carboxymethyl Cellulose

  • Sodium Carboxymethyl Cellulose is used as a flocculating agent, chelating agent, emulsifier, thickening agent, and water-retaining agent. It is primarily used in eye drops to treat dry eyes by soothing irritation and keeping the eyes moist. 
  • It also serves as a stabilizer and thickening agent in various pharmaceutical formulations, particularly in topical and oral products. It belongs to the group of cellulose derivatives.

Side effects of Sodium Carboxymethyl Cellulose

  • Eye irritation and redness with ophthalmic use

  • Stinging and tearing with ophthalmic use

  • Temporary minor burning, stinging or irritation

How Sodium Carboxymethyl Cellulose works

  • Sodium Carboxymethyl Cellulose is a lubricant, pharmaceutical excipient, and thickener.

  • It acts by increasing the viscosity of formulations, such as eye drops, to improve comfort and effectiveness. The higher consistency helps to lubricate and protect the surface of the eye, rendering the formulation more efficacious.

  • Also, as a solubility enhancer in oral medications, it boosts the bioavailability of certain medicines. This means it helps the body to absorb more of the medicine, making it more effective.

  • In topical products like creams and ointments, it acts as an emulsifier and stabiliser. It keeps the different ingredients in these formulations evenly distributed, ensuring their uniform application and effect on your skin.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Sodium Carboxymethyl Cellulose is available for use via the ophthalmic route in the form of eye drops and topically as an ointment.

  • It is also available for topical use in creams and lotions.

Age and Dose Restrictions

  • This medicine is meant for use by adults and children. Specific age restrictions may depend on the formulation and concentration of Sodium Carboxymethyl Cellulose used in the product.

Contraindications

  • This medicine is contraindicated in patients with known hypersensitivity to Sodium Carboxymethyl Cellulose or other cellulose derivatives.

Other Medications to Avoid

  • This combination may interact with other eye medications (such as antihistamine eye drops including ketotifen and olopatadine), and oral medications that alter tear production (such as anticholinergics like atropine).

Overdose and Missed Dose

  • An overdose of Sodium Carboxymethyl Cellulose, especially in eye drop form, is generally not harmful. In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

  • Overdose of Sodium Carboxymethyl Cellulose in topical form is unlikely as it is intended for external use only. Using the prescribed dosage is recommended to avoid any side effects.

  • If a dose is missed, apply the medicine when you remember but skip it if it is almost time for your next scheduled application. Do not double the amount to be applied.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If eye irritation occurs due to eye drops, blinking several times can help spread the eye drop evenly across the eye surface.

  • For topical forms, if irritation occurs, reducing the frequency of application may help alleviate discomfort.

Use in Driving and Operating Machinery

  • The ophthalmic form of Sodium Carboxymethyl Cellulose may cause temporary blurred vision after application. Avoid driving or operating heavy machinery until your vision is clear.

Use in Pregnancy and Lactation

  • It is advisable to consult a doctor before using Sodium Carboxymethyl Cellulose during pregnancy or while breastfeeding. The safety profile has not been fully established under these conditions.

Caution in Other Conditions

  • Patients with severe allergic conditions should exercise caution when using products containing Sodium Carboxymethyl Cellulose due to potential hypersensitivity reactions.

Special Dietary and Lifestyle Recommendations

  • For individuals using Sodium Carboxymethyl Cellulose for dry eyes, increasing hydration by drinking plenty of water can be beneficial.

  • Incorporating omega-3 fatty acids into your diet, found in fish like salmon and nuts like walnuts, can help improve overall eye health.

  • For skin conditions managed by topical forms of Sodium Carboxymethyl Cellulose, maintaining a clean and moisturised skin regimen can enhance the effectiveness of the treatment.

Frequently asked questions

Sodium Carboxymethyl Cellulose is widely used in the pharmaceutical, food, and cosmetic industries. In pharmaceuticals, it is used as an excipient in oral solid dosage forms to enhance medicine bioavailability, as a thickening agent in ophthalmic preparations like eye drops to increase comfort and effectiveness, and as an emulsifier and stabilizer in topical preparations like creams and ointments.

In rare cases, Sodium Carboxymethyl Cellulose might cause allergic reactions such as hives, itching, and rashes. If you experience any sudden or severe symptoms, please consult your doctor immediately.

Yes, Sodium Carboxymethyl Cellulose is generally recognized as safe (GRAS) for use in food manufacturing as a thickener, emulsifier, and stabilizer.

Yes, Sodium Carboxymethyl Cellulose is used as a thickening agent and stabilizer in personal care products including cosmetics.

When used in ophthalmic preparations like eye drops, Sodium Carboxymethyl Cellulose may temporarily cause blurred vision. Therefore, it is advisable to avoid driving or operating machinery until your vision clears.

Sodium Carboxymethyl Cellulose works in eye drops by acting as a lubricant, which helps relieve dryness and irritation in the eyes. It binds to the surface of the eye forming a protective layer that mimics natural tears. This layer increases the moisture retention on the ocular surface, reducing evaporation and maintaining hydration.

Sodium Carboxymethyl Cellulose may affect the absorption or efficacy of concurrently administered medications. It is recommended to keep a list of all products used and consult a doctor before combining medications.

Terms & Conditions


Available medicines for SODIUM CARBOXYMETHYL CELLULOSE
Osmolube Eye Drops 10ml
Osmolube Eye Drops 10ml
Choroid Laboratories Private Limited
Pack of 10 ML
₹102.00
MRP ₹120.00
15.00% OFF
Eycool 0.5 % Eye Drop 10 ML
Eycool 0.5 % Eye Drop 10 ML
Akums Drugs And Pharmacueticals Ltd
Pack of 10 ML
₹114.80
MRP ₹140.00
18.00% OFF
Clymist 0.5 % Eye Drop 10 ML
Clymist 0.5 % Eye Drop 10 ML
Clyde Biotech (p) Ltd
Pack of 10 ML
₹44.71
MRP ₹54.52
18.00% OFF
Lacridrops 0.5 % Eye Drops 10  ML
Lacridrops 0.5 % Eye Drops 10 ML
Renace Pharmacueticals
Pack of 10 ML
₹106.60
MRP ₹130.00
18.00% OFF
Zemoist Eye Drops 10ml
Zemoist Eye Drops 10ml
Entod Pharmaceuticals Ltd
Pack of 10 ML
₹73.80
MRP ₹90.00
18.00% OFF
C Cel 0.5% Eye Drops 10ml
C Cel 0.5% Eye Drops 10ml
Prg Pharma Pvt Ltd
Pack of 10 ML
₹45.10
MRP ₹55.00
18.00% OFF
Tearvet Eye Drops 10ml
Tearvet Eye Drops 10ml
Corneal Labs Pvtltd
Pack of 10 ML
₹114.80
MRP ₹140.00
18.00% OFF

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