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Stavudine

Uses of Stavudine

  • Stavudine, an antiretroviral medication, is primarily used to manage human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS). It belongs to the class of nucleoside reverse transcriptase inhibitors (NRTIs).

  • Additionally, this medicine can be used to prevent the transmission of HIV from a mother to her child during childbirth.

Side effects of Stavudine

  • Headache

  • Nausea and vomiting

  • Diarrhoea

  • Fatigue

  • Rash

How Stavudine works

  • Stavudine is a type of medicine known as a nucleoside reverse transcriptase inhibitor (NRTI).

  • It works by blocking the function of an enzyme called reverse transcriptase, which is needed by the human immunodeficiency virus (HIV) to reproduce itself.

  • When Stavudine gets added to the viral DNA, it results in the termination of the DNA chain. This prevents the replication (multiplication) of HIV within the body's cells.

  • By reducing the amount of HIV in the body, Stavudine helps to enhance the immune system's ability to fight off infections.

Certified content

Written By

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Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Reviewed By

Ashmita Borgohain
Ashmita BorgohainMedical Content Writer & Editor| 12 years

MSc (Applied Genetics)

Expert Advice

Dosage Forms Available

  • Stavudine is available for oral use (capsule, solution).

Age and Dose Restrictions

  • This medicine is intended for use in both adults and paediatric patients. The exact dosage and frequency of administration are determined by the doctor based on the patient's age, overall health status, and response to the treatment.

Contraindications

  • Stavudine is contraindicated in patients with known hypersensitivity or allergy to the medicine.

  • It is also contraindicated in patients with severe liver disease or pancreatitis.

Other Medications to Avoid

  • Stavudine can interact with other antiretroviral medications (like didanosine and zidovudine).

  • It may also interact with certain chemotherapy drugs (such as doxorubicin).

  • It may interact with antiviral medications (like ribavirin).

Overdose and Missed Dose

  • An overdose of Stavudine may lead to symptoms such as nausea, vomiting, headache, and fatigue. If you suspect an overdose, contact your doctor or the nearest healthcare center immediately.

  • If you miss a dose of Stavudine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For nausea and vomiting, try taking the medicine with or after a meal.

  • If you experience diarrhoea, drink plenty of water to stay hydrated.

  • Headache can often be managed by ensuring proper rest and hydration.

Use in Driving and Operating Machinery

  • Stavudine may cause dizziness or fatigue. Therefore, it is advised not to drive or operate heavy machinery until you are sure how the medicine affects you.

Use in Pregnancy and Lactation

  • Stavudine should only be used during pregnancy and breastfeeding if the potential benefits outweigh the risks. Please consult your doctor since they will determine this.

Caution in Other Conditions

  • Caution is advised in patients with a history of peripheral neuropathy, pancreatitis, kidney disease, liver problems, and diabetes while using Stavudine.

Special Dietary and Lifestyle Recommendations

  • Patients on antiretroviral therapy may benefit from a balanced diet that includes plenty of fruits, vegetables, whole grains, lean proteins, and healthy fats.

  • Regular physical activity also plays a crucial role in maintaining overall health and well-being.

  • Alcohol should be avoided as it can interfere with the effectiveness of the medication and exacerbate its side effects.

  • Smoking cessation is recommended as smoking can have a negative impact on your overall health and potentially worsen HIV symptoms.

Frequently asked questions

No, Stavudine is not a steroid. It is an antiretroviral medication used to help manage human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS).

There is no specific reference suggesting that Stavudine directly affects sleep. However, some of the side effects like fatigue could indirectly affect your sleep pattern. If you notice any changes in your sleep pattern after starting this medicine, it is important to consult your doctor.

There are no specific studies or references suggesting that Stavudine directly impacts fertility in humans. However, if you have concerns about fertility while taking this medication, it is crucial to discuss them with your doctor.

There are no specific dietary restrictions mentioned for patients taking Stavudine. However, a healthy diet can enhance the overall health and wellness of individuals living with HIV or AIDS.

Yes, it is safe to take Stavudine daily as prescribed by your doctor. It is used as part of a combination therapy to manage HIV infection.

The effects of Stavudine on viral load may be seen within a few weeks of starting treatment. However, immune system improvement may require several months. Individual results may vary depending on your condition.

The duration of treatment with Stavudine can vary from person to person. It depends on the individual's health condition, progress, and response to the medication.

Terms & Conditions


Available medicines for STAVUDINE
Stavir 30 MG Capsule 10
Stavir 30 MG Capsule 10
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Pack of 10 Units
₹28.95
MRP ₹35.31
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Stavir 30 MG Capsule 60
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Pack of 60 Units
₹197.05
MRP ₹240.30
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Stavex 40 MG Capsule 10
Stavex 40 MG Capsule 10
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Pack of 10 Units
₹73.80
MRP ₹90.00
18.00% OFF
Stavex 30 MG Capsule 10
Stavex 30 MG Capsule 10
Veritaz Healthcare Ltd
Pack of 10 Units
₹64.58
MRP ₹78.75
18.00% OFF
Virostav 30 MG Tablet 10
Virostav 30 MG Tablet 10
Sun Pharmaceutical Industries Ltd
Pack of 10 Units
₹31.16
MRP ₹38.00
18.00% OFF
Stahope 40 MG Tablet 60
Stahope 40 MG Tablet 60
Macleods Pharmaceuticals Pvt.ltd
Pack of 60 Units
₹194.78
MRP ₹237.54
18.00% OFF
Virostav 40 MG Tablet 10
Virostav 40 MG Tablet 10
Sun Pharmaceutical Industries Ltd
Pack of 10 Units
₹35.26
MRP ₹43.00
18.00% OFF
Stavir 40 MG Capsule 10
Stavir 40 MG Capsule 10
Cipla Ltd.
Pack of 10 Units
₹32.46
MRP ₹39.59
18.00% OFF

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