Stavudine

Dosage Forms Available

• Stavudine is available for oral use (capsule, solution).

Age and Dose Restrictions

• This medicine is intended for use in both adults and paediatric patients. The exact dosage and frequency of administration are determined by the doctor based on the patient's age, overall health status, and response to the treatment.

Contraindications

• Stavudine is contraindicated in patients with known hypersensitivity or allergy to the medicine.

• It is also contraindicated in patients with severe liver disease or pancreatitis.

Other Medications to Avoid

• Stavudine can interact with other antiretroviral medications (like didanosine and zidovudine).

• It may also interact with certain chemotherapy drugs (such as doxorubicin).

• It may interact with antiviral medications (like ribavirin).

Overdose and Missed Dose

• An overdose of Stavudine may lead to symptoms such as nausea, vomiting, headache, and fatigue. If you suspect an overdose, contact your doctor or the nearest healthcare center immediately.

• If you miss a dose of Stavudine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• For nausea and vomiting, try taking the medicine with or after a meal.

• If you experience diarrhoea, drink plenty of water to stay hydrated.

• Headache can often be managed by ensuring proper rest and hydration.

Use in Driving and Operating Machinery

• Stavudine may cause dizziness or fatigue. Therefore, it is advised not to drive or operate heavy machinery until you are sure how the medicine affects you.

Use in Pregnancy and Lactation

• Stavudine should only be used during pregnancy and breastfeeding if the potential benefits outweigh the risks. Please consult your doctor since they will determine this.

Caution in Other Conditions

• Caution is advised in patients with a history of peripheral neuropathy, pancreatitis, kidney disease, liver problems, and diabetes while using Stavudine.

Special Dietary and Lifestyle Recommendations

• Patients on antiretroviral therapy may benefit from a balanced diet that includes plenty of fruits, vegetables, whole grains, lean proteins, and healthy fats.

• Regular physical activity also plays a crucial role in maintaining overall health and well-being.

• Alcohol should be avoided as it can interfere with the effectiveness of the medication and exacerbate its side effects.

• Smoking cessation is recommended as smoking can have a negative impact on your overall health and potentially worsen HIV symptoms.