Tenofovir Disoproxil Fumarate

Dosage Forms Available

• Tenofovir Disoproxil Fumarate is available in the form of tablets and oral powder for oral administration.

• The oral powder form should be mixed with soft food prior to consumption, while the tablet should be swallowed without chewing or crushing.

Age and Dose Restrictions

• This medicine is intended for use by adults and children.

• For children with HIV-1 infection, it is suitable from age 2 years and above.

• In cases of chronic Hepatitis B infection, it is appropriate for use in children aged 12 years and above who weigh at least 35 kg.

Contraindications

• Tenofovir Disoproxil Fumarate is contraindicated in patients who have demonstrated hypersensitivity to any of the components of this medicine.

Other Medications to Avoid

• Tenofovir disoproxil fumarate may interact with antiretroviral medicines (e.g., didanosine), nephrotoxic medications (e.g., aminoglycosides), anticonvulsants (e.g., carbamazepine, phenytoin), antimycobacterials (e.g., rifampin) and hepatotoxic medicines (e.g., acyclovir, valacyclovir).

Overdose and Missed Dose

• An overdose of Tenofovir Disoproxil Fumarate can lead to harmful effects on the body. If you suspect an overdose, seek immediate medical attention.

• If a dose of this medicine is missed, it should be taken as soon as possible. If it is close to the time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double up the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage side effects such as diarrhoea and nausea.

• Taking this medication with food may help reduce gastrointestinal upset.

Use in Driving and Operating Machinery

• Tenofovir Disoproxil Fumarate may cause side effects like fatigue and dizziness that may impair your ability to drive or operate machinery.

Use in Pregnancy and Lactation

• Consultation with a doctor is advised before using Tenofovir Disoproxil Fumarate during pregnancy or while breastfeeding.

Caution in Other Conditions

• Individuals with kidney problems should exercise caution when using Tenofovir Disoproxil Fumarate, as this medication may affect kidney function.

Special Dietary and Lifestyle Recommendations

• Maintain a balanced diet rich in fruits, vegetables, whole grains, lean proteins, and low-fat dairy to support overall health.

• Regular physical activity can improve general health and immunity.

• Avoid smoking and limit alcohol consumption to prevent further liver damage if you have Hepatitis B.

• Use barrier methods of contraception (like condoms) to prevent transmission of HIV during sexual activity.

• Practice good hygiene habits, like regular hand washing, to prevent the spread of Hepatitis B.