Tenvir 300 Mg Tablet 30

Tenvir Tablet 30

Cipla Ltd.

Bottle of 30 Units

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Composition

Tenofovir Disoproxil Fumarate (300 Mg)

Tenvir Tablet is primarily used to manage HIV-1 infection, a condition caused by the human immunodeficiency virus. It falls under the category of antiretroviral medications, specifically the class known as nucleotide reverse transcriptase inhibitors (NRTIs).

In addition to its main use in managing HIV-1 infection, this tablet is also used for the management of chronic hepatitis B virus (HBV) infection. Both these uses involve controlling viral infections to prevent them from causing further damage to your body.

Before you start taking this medicine, it's important to consult your doctor for the correct dosage and frequency. Your doctor needs to be aware of any pre-existing conditions or ongoing medications you're taking, as these can interfere with how this tablet works. If you experience side effects while on this medication, let your doctor know straight away.

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Tenvir Tablet is used for the following:

Managing HIV-1 infection in adults and children over 2 years old: This medicine is combined with other antiretroviral agents to control this condition.
Handling chronic hepatitis B virus (HBV) infection in adults and children over 12 years old: Tenvir Tablet helps control this viral liver infection.

Follow these instructions while taking Tenvir Tablet:

Swallow the tablet whole with a glass of water.
You can take this medicine with or without food.
Avoid crushing or chewing the tablet.
Always take the recommended dose, don't exceed it without consulting your doctor.
Don't stop taking this medicine without speaking to your doctor first. It's crucial to complete the course for effective management of your condition.

Tenvir Tablet is taken orally.

Taking Tenvir Tablet can cause the following common side effects:

Rash
Diarrhoea
Headache
Pain
Depression
Nausea
Asthenia: This means abnormal physical weakness or lack of energy, which you may experience after taking this medicine.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Tenvir Tablet . However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Tenvir Tablet with food to lessen this effect.
Nausea: If you are feeling nauseated, consider taking this medicine after meals.

Tenvir Tablet contains tenofovir disoproxil fumarate (300 mg), which acts on your body in multiple ways:

Conversion to Active Form: After you take Tenvir Tablet, it gets converted into an active form called tenofovir inside your body.
Inhibits Viral Replication: Tenofovir competes with the natural building blocks of DNA inside viruses like HIV-1 and HBV, effectively preventing them from replicating.
Leads to DNA Chain Termination: Once incorporated into the viral DNA, tenofovir causes premature termination of the DNA chain. This stops the virus from replicating further and helps control the infection in your body.

Pregnancy

It's recommended to consult your doctor before taking this medicine during pregnancy. Your doctor can best advise if the benefits outweigh any potential risks.

Breastfeeding

Mothers receiving Tenvir Tablet are advised not to breastfeed as the active ingredient may pass into breast milk and affect the baby.

Alcohol

Caution is advised regarding alcohol consumption while on this medication.

Liver

Tenvir Tablet could lead to severe hepatomegaly with steatosis, a liver condition. If you have any liver-related health issues, talking to your doctor before starting this medication is advisable.

Kidney

Tenvir Tablet has been known to cause renal impairment in some cases. If you have a history of kidney problems, consulting your doctor before starting this medication is recommended.

Using Machines & Driving

No specific data suggest that Tenvir Tablet impacts your ability to drive or operate machinery. However, any medicine can cause side effects which could affect these abilities. Be careful and consult your doctor if you experience anything unusual.

Allergy

If you have known allergies to tenofovir disoproxil fumarate or any other components of Tenvir Tablet , it's important that you discuss this with your doctor before starting the medication.

Children

Tenvir Tablet is not recommended for children under 2 years of age suffering from HIV-1 infection or under 12 years suffering from chronic HBV infection. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Tenvir Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Tenvir Tablet interacts with the following medicines:

Medicines Eliminated by Active Tubular Secretion: Medications such as cidofovir, acyclovir, valacyclovir, ganciclovir, and valganciclovir may interact with Tenvir Tablet. This may increase the concentration of either tenofovir or the co-administered medicine in your system.
Renal Function Reducing Medicines: Medicines that decrease renal function can increase concentrations of tenofovir. These could include certain types of diuretics like furosemide.
Adefovir Dipivoxil: Do not administer Tenvir Tablet with HEPSERA (adefovir dipivoxil), as it may lead to adverse reactions.

Drug-Food Interactions

There are no specific known interactions between Tenvir Tablet and food. It can be taken orally with or without food.

Drug-Disease Interactions

Tenvir Tablet interacts with the following diseases:

Hepatitis B: If you have chronic hepatitis B and discontinue the use of TDF, it might lead to a severe acute exacerbation of your hepatitis.
Bone Diseases: TDF has been associated with decreases in bone mineral density. If you have a history of pathologic bone fracture or risk factors for bone loss, this could be problematic.

Daily Dose

The daily dose of Tenvir Tablet should be taken as directed by your doctor. This dosage may vary based on personal factors such as the severity of your condition and your body's response to the medication. It's crucial to adhere to the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

In case you accidentally take more than the recommended dose of Tenvir Tablet, you may experience symptoms such as headache, diarrhoea, and nausea. If these symptoms persist, inform your doctor.

Missed Dose

If you miss a dose of Tenvir Tablet, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never double up on doses without consulting your doctor.

Store Tenvir Tablet in its original container, keeping it tightly closed.
Avoid exposing this medicine to excessive light, heat, or moisture.
Keep it out of sight and reach of children.
Ensure you use the product before its expiry date.

A balanced diet plays a key role in managing HIV or chronic hepatitis B: Aim for food rich in whole grains, lean proteins, and fresh fruits and vegetables.
Regular exercise can improve your overall wellbeing: Incorporate moderate physical activities such as walking or yoga into your daily schedule to help manage your condition better. Remember, always consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Nucleotide Reverse Transcriptase Inhibitor
Therapeutic Category	Antiretroviral Medicine
Available Dosage Types	Tablet
Habit Forming	No
Ailment	HIV-1 Infection, Chronic Hepatitis B

What is Tenvir Tablet used for?

Tenvir Tablet is used for managing HIV-1 infection and chronic Hepatitis B virus infections in adults and certain paediatric patients.

How does Tenvir Tablet work?

It contains tenofovir disoproxil fumarate, which inhibits the activity of certain enzymes in the viruses, slowing down their growth and spread in your body.

What should I do if I'm allergic to any component of Tenvir Tablet?

If you're allergic to any component of the Tenvir Tablet, avoid using it. Always consult your doctor for an alternative medicine.

Are there any side effects of Tenvir Tablet?

Common side effects include rash, diarrhoea, headache, pain, depression, weakness, and nausea.

Can I take Tenvir Tablet during pregnancy or while breastfeeding?

The safety of Tenvir Tablet during pregnancy or while breastfeeding isn't established. Consult your doctor if you are pregnant or nursing.

Are there any warnings or precautions while taking Tenvir Tablet?

Yes, kidney impairment, lactic acidosis, severe hepatitis B exacerbation, HIV-1 resistance in coinfected patients and bone loss are some concerns. Consult your doctor before use.

Does Tenvir Tablet interact with other medicines?

Yes, it may interact with medicines like cidofovir, acyclovir or adefovir dipivoxil. Discuss all your current medicines with your doctor before starting Tenvir Tablet.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

Gilead Sciences, Inc. (2012). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021356s042,022577s002lbl.pdf
Gilead Sciences, Inc. (2019). HIGHLIGHTS OF PRESCRIBING INFORMATION. https://www.gilead.com/-/media/files/pdfs/medicines/hiv/viread/viread_pi.pdf
Teva Canada Limited. (2017). PRODUCT MONOGRAPH. https://pdf.hres.ca/dpd_pm/00040336.PDF
Tenofovir disoproxil fumarate FDA label | NIH. (n.d.). https://clinicalinfo.hiv.gov/en/drugs/tenofovir-disoproxil-fumarate/fda-label
Tenofovir disoproxil: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00300

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