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Thiamine

Uses of Thiamine

  • Thiamine is used to manage thiamine deficiencies and related disorders, such as Beriberi (muscle weakness, numbness, and poor reflexes) and Wernicke-Korsakoff syndrome (memory loss, confusion, and vision problems). 
  • It is an essential part of B-complex vitamin supplements and helps treat and prevent these conditions caused by thiamine deficiency.

Side effects of Thiamine

Potential side effects of Thiamine when taken in excess may include:

  • Mild allergic reactions such as rash or itching

  • Swelling

  • Gastrointestinal upset including nausea, vomiting and diarrhoea

  • Headache

  • Fatigue

How Thiamine works

  • Thiamine is a crucial B-complex vitamin.

  • It plays a critical role as a coenzyme in carbohydrate metabolism. It is essential for the conversion of pyruvate to acetyl-CoA in the Krebs cycle, which is crucial for energy production. Thiamine also supports nerve function by aiding in the synthesis of neurotransmitters.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Thiamine is available for oral use in the form of tablets and capsules.

  • It can also be acquired as a liquid solution for those who may have difficulty swallowing pills.

  • For more direct and immediate absorption, Thiamine is available as an injectable solution which is administered through the intramuscular or intravenous routes.

Age and Dose Restrictions

  • Thiamine supplements are suitable for adults and children alike, ensuring broad accessibility to those who might need them.

Contraindications

  • This medicine is contraindicated in individuals with a known allergy to Thiamine or any of the inactive components used in its formulations.

Other Medications to Avoid

  • Thiamine may interact with diuretics (such as furosemide and hydrochlorothiazide), and antibiotics (like trimethoprim), leading to potential negative effects on Thiamine levels or absorption in the body.

  • It is essential to consult a doctor before starting any new medications while taking Thiamine, especially those mentioned.

Overdose and Missed Dose

  • An overdose, though rare due to its water-soluble nature, might lead to symptoms like nausea or restlessness. In such cases, it is advisable to seek medical advice immediately.

  • If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. In that case, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If experiencing mild nausea or stomach upset with Thiamine, try taking it with food or a glass of water.

  • Administering the medicine at a different time of day may help if sleep disturbances occur.

Use in Driving and Operating Machinery

  • Thiamine does not typically affect your ability to drive or operate machinery. No specific precautions are usually required.

Use in Pregnancy and Lactation

  • Pregnant or breastfeeding women should consult their doctor before beginning Thiamine supplementation to ensure safety during these sensitive periods.

Caution in Other Conditions

  • Individuals with conditions affecting absorption from the digestive tract, such as Crohn's disease or gastric bypass surgery, should discuss with their doctor how best to manage their Thiamine levels.

Special Dietary and Lifestyle Recommendations

  • Incorporating thiamine-rich foods into your diet such as whole grains, pork, nuts, and seeds can help prevent deficiencies.

  • For individuals recovering from alcohol use disorder or those with high stress, it might be beneficial to monitor dietary intake to ensure sufficient Thiamine levels are maintained.

  • Regular monitoring of thiamine levels might be advisable for people with malabsorption issues or chronic illnesses linked with lower vitamin B1 levels.

Frequently asked questions

Yes, Thiamine plays a crucial role in energy metabolism. It helps convert carbohydrates into glucose, which the body utilises for energy.

Thiamine is essential for the proper functioning of the nervous system. It aids in the synthesis of neurotransmitters like acetylcholine and gamma-aminobutyric acid (GABA), which are involved in nerve signalling and muscle function.

The effects of Thiamine can be noticed within days to weeks, depending on the severity of the deficiency and the purpose of supplementation.

Thiamine deficiency can lead to serious health problems such as muscle weakness, paralysis, heart failure, confusion, vision problems, memory loss, and damage to the nervous system.

You can increase your Thiamine intake naturally by consuming foods rich in this vitamin. These include whole grains, legumes, nuts, seeds, pork, and fortified cereals.

Yes, chronic alcohol consumption can lead to Thiamine deficiency as it interferes with the absorption of this vitamin in the body.

Thiamine plays a role in energy metabolism, so a deficiency might decrease appetite, while supplementation could help normalize it.

Terms & Conditions


Thiamine in other salts

ASCORBIC ACID + BIOTIN + CALCIUM PANTOTHENATE + FOLIC ACID + METHYLCOBALAMIN + NIACINAMIDE + RIBOFLAVIN + THIAMINE MONONITRATE + ZINC SULPHATEBIOTIN + CALCIUM PANTOTHENATE + COPPER SULPHATE + COPPER SULPHATE PENTAHYDRATE + CYANOCOBALAMIN / VITAMIN B12 + FERROUS SULPHATE + MAGNESIUM OXIDE + MAGNESIUM SULPHATE MONOHYDRATE + NICOTINAMIDE + PYRIDOXINE HYDROCHLORIDE + RIBOFLAVIN / VITAMIN B2 + SODIUM BORATE + SODIUM MOLYBDATE DIHYDRATE + THIAMINE MONONITRATE + TOCOPHERYL ACETATE + TOTAL PHOSPHOROUS + TRIBASIC CALCIUM PHOSPHATE + VITAMIN A / RETINOL + VITAMIN C / ASCORBIC ACID + VITAMIN D3 (CHOLECALCIFEROL) + ZINC SULPHATEBIOTIN + CYANOCOBALAMIN / VITAMIN B12 + ELEMENTAL CHROMIUM + ELEMENTAL COPPER + ELEMENTAL MANGANESE + FOLIC ACID + GRAPE SEED EXTRACT + IODINE + MAGNESIUM + RIBOFLAVIN / VITAMIN B2 + SELENIUM + THIAMINE / VITAMIN B1 + VITAMIN A / RETINOL + VITAMIN B3 / NIACIN + VITAMIN B5 / PANTOTHENIC ACID + VITAMIN B6 / PYRIDOXINE + VITAMIN C / ASCORBIC ACID + VITAMIN D3 (CHOLECALCIFEROL) + VITAMIN E + ZINCCALCIUM PANTOTHENATE + CYANOCOBALAMIN + NICOTINAMIDE + PYRIDOXINE HYDROCHLORIDE + RIBOFLAVIN + THIAMINE MONONITRATEALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + THIAMINE MONONITRATE + VITAMIN B6 / PYRIDOXINEBIOTIN + CALCIUM PANTOTHENATE + CYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINE + VITAMIN C / ASCORBIC ACIDCYANOCOBALAMIN / VITAMIN B12 + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINEALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + PYRIDOXINE HYDROCHLORIDE + THIAMINE MONONITRATECHOLINE + FLAXSEED OIL + L-LYSINE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN A / RETINOL + VITAMIN B3 / NIACIN + VITAMIN B5 / PANTOTHENIC ACID + VITAMIN C / ASCORBIC ACID + VITAMIN D3 (CHOLECALCIFEROL) + VITAMIN ETHIAMINE / VITAMIN B1CYANOCOBALAMIN / VITAMIN B12 + D-PANTHENOL + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINED-PANTHENOL + L-LYSINE + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINECYANOCOBALAMIN / VITAMIN B12 + D-PANTHENOL + L-LYSINE + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINETHIAMINE HYDROCHLORIDEALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + THIAMINE + VITAMIN B6 / PYRIDOXINE
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