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Thyroxine

DRUGS FOR HYPOTHYROIDISM

Uses of Thyroxine

  • Thyroxine Sodium is used to treat hypothyroidism, a condition characterized by low levels of thyroid hormone, leading to a slowed metabolism. 
  • This hormone is essential for normal growth, development, and regulating the body's energy use (metabolic rate). It also plays a role in digestion, heart and muscle function, brain development, and bone health.

Side effects of Thyroxine

  • Increased appetite
  • Weight loss
  • Diarrhoea
  • Muscle spasm
  • Headache

How Thyroxine works

Thyroxine Sodium works by controlling DNA transcription and protein synthesis. Triiodothyronine (T3) and L-thyroxine (T4) enter the cell nucleus and attach to thyroid receptor proteins linked to DNA. This complex activates gene transcription and the production of messenger RNA and cytoplasmic proteins. The main physiological effects of thyroid hormones are primarily generated by T3, with the majority (about 80%) formed from T4 through deiodination in peripheral tissues.

Certified content

Written By

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Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Thyroxine Sodium is available for use via oral route (tablet).

Age and Dose Restrictions

  • This medicine is meant for adults and children based on body weight.

Contraindications

  • This medicine is contraindicated in patients with known allergies to Thyroxine Sodium and patients with uncorrected adrenal insufficiency.

Other Medications To Avoid With This Medicine

  • Some medications that interact with Thyroxine Sodium are anti-diabetic drugs like metformin, anti-acid medications like cimetidine, esomeprazole, and sucralfate, bile acid sequestrants like colesevelam, cholestyramine, estrogen-containing oral contraceptives, blood thinners like warfarin, medicines used to manage heart conditions like digitalis, and antidepressants like amitriptyline and maprotiline.

Overdose and Missed Dose

  • An overdose of this medication may cause irregular heartbeat, muscle spasms, headache, nervousness, irritability, difficulty sleeping, tremors, muscle weakness, increased appetite, weight loss, diarrhoea, heat intolerance, menstrual irregularities, and skin rash. If you observe these symptoms, inform your doctor and follow the advice accordingly.
  • If you forget to take this medicine, take it as soon as you remember. But avoid repeating the dose.

Management Of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

Use In Driving And Operating Machinery

  • This medication will not impair your ability to drive or operate machinery.

Use in Pregnancy and Lactation

  • This medicine may be taken during pregnancy and breastfeeding. However, it is always recommended to ask your doctor for advice before taking any medicine if you are pregnant, planning to become pregnant, or breastfeeding. 

Caution In Other Conditions

  • Patients with heart issues, and diabetes should exercise caution while taking this medicine.

Special Dietary & Lifestyle Recommendation

  • The thyroid gland relies on iodine to produce its hormone, so it's important to include iodized table salt in your diet. However, excessive intake can lead to hyperthyroidism, so moderation is key. Additionally, individuals with hypothyroidism may benefit from a balanced diet rich in nutrients and a regular dose of Thyroxine Sodium including a variety of vegetables in your meals can be beneficial.
  • Hypothyroidism often results in calcium and Vitamin D deficiencies, so incorporating calcium-enriched foods is recommended. Since hypothyroidism can slow metabolism, increasing protein intake with foods like eggs, milk, and pulses may help boost metabolism. Engaging in daily yoga and aerobics exercises can promote relaxation and enhance metabolism.
  • For those with hypothyroidism, prioritizing vegetables, fruits, and lean meats is advisable as these foods are low in calories and may aid in weight management. It's important to avoid Goitrogens, which can interfere with thyroid function. Foods like soy products, cabbage, broccoli, kale, and spinach should be consumed in moderation to support thyroid health.

Frequently asked questions

This medicine's onset of action may require a few weeks for full efficacy to be realised.

If you're allergic to this medicine, don't take it. Seek medical help right away if you have any allergic reactions. Also, exercise caution while taking this combination if you have heart disease and uncorrected adrenal insufficiency.

Please do not discontinue Thyroxine Sodium without consulting your doctor first. Abruptly stopping the medication may result in the return of symptoms.

No special precautions need to be taken for patients with kidney and liver issues while taking Thyroxine Sodium. However, it is always recommended to ask your doctor for advice if you have kidney or liver issues.

This medication may affect your fertility. Please discuss it with your doctor before taking it.

Terms & Conditions


Thyroxine in other salts

Available medicines for THYROXINE
Thyronorm 100mcg Tablet 120
Thyronorm 100mcg Tablet 120
Abbott India Ltd.
Pack of 120 Units
₹145.47
MRP ₹177.40
18.00% OFF
Thyronorm 50mcg Tablet 120
Thyronorm 50mcg Tablet 120
Abbott India Ltd.
Pack of 120 Units
₹117.67
MRP ₹138.43
15.00% OFF
Thyronorm 75mcg Tablet 120
Thyronorm 75mcg Tablet 120
Abbott India Ltd.
Pack of 120 Units
₹158.16
MRP ₹192.88
18.00% OFF
Thyronorm 25mcg Tablet 120
Thyronorm 25mcg Tablet 120
Abbott India Ltd.
Pack of 120 Units
₹159.40
MRP ₹194.39
18.00% OFF
Thyrox 25 Tablet 120
Thyrox 25 Tablet 120
Macleods Pharmaceuticals Pvt.ltd
Pack of 120 Units
₹159.40
MRP ₹194.39
18.00% OFF
Eltroxin 50mcg Tablet 120
Eltroxin 50mcg Tablet 120
Glaxosmithkline Pharmaceuticals Ltd.
Pack of 120 Units
₹98.03
MRP ₹119.55
18.00% OFF
Thyrox 50 Tablet 120
Thyrox 50 Tablet 120
Macleods Pharmaceuticals Pvt.ltd
Pack of 120 Units
₹113.51
MRP ₹138.43
18.00% OFF
Eltroxin 100mcg Tablet 120
Eltroxin 100mcg Tablet 120
Glaxosmithkline Pharmaceuticals Ltd.
Pack of 120 Units
₹145.48
MRP ₹177.41
18.00% OFF

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