Vinpocetine
Uses of Vinpocetine
Vinpocetine is primarily used to manage cognitive disorders such as memory loss, attention deficit, and mental confusion, especially in older individuals. It belongs to the group of Nootropic medications.
Additionally, Vinpocetine has been used to manage Alzheimer's disease and other types of dementia, and to enhance recovery after an ischemic stroke. It may also be beneficial in managing certain hearing and visual problems related to poor blood circulation.
Side effects of Vinpocetine
Gastrointestinal disturbances such as nausea and diarrhoea
Cardiovascular effects including low blood pressure, rapid heartbeat
Neurological effects like headache and dizziness
Sleep disturbances
Nervousness
How Vinpocetine works
Vinpocetine is a type of nootropic medicine.
It primarily works by increasing the blood flow to the brain. This is done by widening the blood vessels and reducing the thickness of the blood, enhancing circulation in the brain.
Vinpocetine also shields brain cells from potential damage caused by conditions such as ischemia (lack of oxygen) or hypoxia (low oxygen levels).
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Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Vinpocetine is available for use via the oral route in the form of tablets and capsules.
Age and Dose Restrictions
Vinpocetine is intended for use by adults of age above 18 years.
Contraindications
Vinpocetine is contraindicated in individuals with hypersensitivity to Vinpocetine or any of its components.
It should not be used by those with active bleeding or a history of bleeding disorders.
It is also contraindicated in patients with severe hypotension or unstable blood pressure.
Other Medications to Avoid
Vinpocetine may interact with anticoagulants and antiplatelet medicines (such as warfarin and clopidogrel), medications that lower blood pressure (like lisinopril and atenolol), calcium channel blockers (such as amlodipine and verapamil), and glucocorticoids and immunosuppressants (like prednisone and tacrolimus).
Overdose and Missed Dose
An overdose of Vinpocetine may lead to gastrointestinal disturbances, cardiovascular effects such as low blood pressure and rapid heartbeat, and neurological effects like headache, dizziness, sleep disturbances, and nervousness. If you observe these symptoms, inform your doctor immediately and follow their advice.
If you forget to take your regular dose of Vinpocetine, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed one and continue with your regular dosing schedule.
Management of Side Effects
Most side effects of Vinpocetine are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water may help to manage any gastrointestinal disturbances such as nausea and diarrhea.
Resting in a quiet, dark room may help to manage headaches.
If you feel dizzy, make sure to sit or lie down until the feeling passes.
Use in Driving and Operating Machinery
Vinpocetine may cause dizziness, sleep disturbances, and nervousness. Therefore, it is advisable not to drive or operate heavy machinery if you experience these side effects after taking the medicine.
Use in Pregnancy and Lactation
Always consult your doctor before using this medicine during these periods.
Caution in Other Conditions
Patients with low blood pressure should exercise caution when taking Vinpocetine as it may further lower blood pressure.
It is also advisable to discontinue Vinpocetine at least two weeks before any scheduled surgery to minimise the risk of bleeding.
Special Dietary and Lifestyle Recommendations
Regular physical activity can help improve circulation, which may enhance the effectiveness of Vinpocetine.
Eating a balanced diet rich in vitamins and minerals can support overall brain health.
Adequate rest and sleep can help maintain optimal cognitive function.
Frequently asked questions
Is Vinpocetine safe for long-term use?
Vinpocetine is generally well-tolerated. It is advisable to use Vinpocetine under medical supervision and for the shortest duration necessary.
Can Vinpocetine improve my memory even if I am healthy?
Some studies suggest that Vinpocetine may enhance memory and cognitive performance in healthy adults.
Is Vinpocetine available over the counter or do I need a prescription?
In India, Vinpocetine is typically available only through a prescription. It is not commonly sold as an over-the-counter dietary supplement. It is important to consult with a healthcare provider before starting Vinpocetine or any new medication, as they can provide guidance on its use and ensure it is appropriate for your condition.
Is Vinpocetine a natural substance or a synthetic compound?
Vinpocetine is a synthetic compound. It is derived from vincamine, an alkaloid found in the periwinkle plant (Vinca minor). While it is not naturally occurring, it is based on a natural substance.
Are there any natural alternatives to Vinpocetine?
Vinpocetine itself is derived from a natural source, the periwinkle plant (Vinca minor). However, it is important to note that natural does not necessarily mean safer or more effective. If you are considering alternative options, consult your doctor first for advice tailored to your specific circumstances.
Can I stop taking Vinpocetine abruptly?
As with any medicine, you should not stop taking Vinpocetine without first consulting your doctor as this could cause withdrawal symptoms or worsen your condition.
Does Vinpocetine have any effect on mood or emotions?
While there is no direct link between Vinpocetine and mood regulation, this medicine may improve cognitive function including memory and attention, which could potentially impact mood indirectly. However, this is highly individual and can vary from person to person.
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