Vonoprazan

Dosage Forms Available

• Vonoprazan is available for use as oral tablets.

• This medicine is administered orally.

Age and Dose Restrictions

• This medicine is meant for use in adults. Specific guidance for children's use has not been provided, suggesting it is primarily intended for adult patients.

Contraindications

• Vonoprazan is contraindicated in patients with a known hypersensitivity to the medicine or any of its ingredients.

Other Medications to Avoid

• This medicine may interact with antibiotics (such as clarithromycin), chemotherapy agents (like methotrexate), cardiac glycosides (including digoxin), anticoagulants (such as warfarin), and antiretrovirals (like atazanavir).

Overdose and Missed Dose

• An overdose of Vonoprazan may lead to an increased incidence of its side effects such as diarrhoea and headache. If you suspect an overdose, it is important to seek medical attention promptly.

• If you miss a dose of Vonoprazan, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• If experiencing mild diarrhoea, consider taking the medication with food or increasing fluid intake.

• For headaches, adjusting the timing of the medication might help mitigate this side effect.

Use in Driving and Operating Machinery

• Vonoprazan does not specifically impair your ability to drive or operate machinery. However, if you experience side effects like headaches or dizziness, it may be wise to avoid such activities until these effects subside.

Use in Pregnancy and Lactation

• Vonoprazan should only be used during pregnancy or lactation if the potential benefits justify the potential risks. It is important to consult a doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

• Patients with severe liver problems should exercise caution when taking Vonoprazan due to the metabolism of the medicine being potentially affected by liver functionality.

• It is also advisable for individuals with serious kidney issues to consult a doctor before using Vonoprazan as dosage adjustments may be necessary.

Special Dietary and Lifestyle Recommendations

• To manage conditions like gastroesophageal reflux disease (GERD) which Vonoprazan is used for, consider eating smaller, more frequent meals instead of three large ones.

• Avoid foods that trigger reflux such as spicy foods, chocolate, caffeine, and acidic fruits.

• If you are dealing with GERD or erosive esophagitis, elevating the head of your bed by a few inches can help reduce symptoms at night.

• Reducing alcohol intake can also decrease stomach acid production which complements the action of Vonoprazan.

• Smoking cessation is advised as smoking can increase stomach acidity and delay healing of the stomach lining.