10 Li M 500 Sr Tablet 10

Apex Laboratories Ltd.

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MRP ~~₹128.60~~

₹105.45

₹12.86/UNITS

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Composition

Metformin (500 Mg) + Teneligliptin (20 Mg)

10 Li M 500 Sr Tablet 10 is primarily used to manage type 2 diabetes mellitus in adults. This combination medicine is part of the antidiabetic class of medications.

In addition to its primary use, this tablet helps improve the body's glucose tolerance, thereby aiding in the overall management of blood sugar levels in individuals with type 2 diabetes. It also plays a crucial role when monotherapy with either of its components isn't sufficient to achieve control over blood sugar levels.

Before you start taking this medicine, consult your doctor for the correct dosage and frequency based on your condition. It's essential to inform your doctor about any pre-existing conditions or ongoing medications before starting this medication. If you notice any side effects while taking the medicine, notify your doctor immediately. For optimal results, continue with the medication for the duration prescribed by your doctor.

10 Li M 500 Sr Tablet 10 is used to manage type 2 diabetes mellitus.

Directions for Use of 10 Li M 500 Sr Tablet 10

Swallow the tablet whole with a glass of water during a meal.
Do not split, crush, or chew the tablet; it must be swallowed whole.
Never exceed the recommended dose without consulting your doctor.
It's crucial not to stop taking this medicine without speaking to your doctor first.

10 Li M 500 Sr Tablet 10 is taken orally.

Side Effects of 10 Li M 500 Sr Tablet 10

Taking 10 Li M 500 Sr Tablet 10 may cause the following side effects:

Diarrhoea
Nausea
Vomiting
Abdominal discomfort
Headache
Indigestion

Managing the Side Effects:

Most side effects are temporary and generally harmless which resolve upon discontinuing the use of 10 Li M 500 Sr Tablet 10. However, if you experience any serious side effects or worsening of any symptoms, please consult your doctor.

Here are a few tips for managing common side effects:

Diarrhoea: You could try taking your medication with food.
Indigestion: If you're experiencing indigestion, consider taking this medicine after meals to lessen this effect.

10 Li M 500 Sr Tablet 10 combines two active ingredients:

Metformin (500 mg): As a biguanide antihyperglycemic agent, metformin enhances glucose tolerance in individuals with type 2 diabetes. It accomplishes this by reducing glucose production in the liver and decreasing glucose absorption in the intestines. Additionally, it helps increase peripheral glucose uptake and utilisation, thereby improving insulin sensitivity.
Teneligliptin (20 mg): Classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor, teneligliptin works by slowing down the inactivation of incretin hormones. This process increases their concentrations in the bloodstream, leading to reduced fasting and postprandial glucose levels in a glucose-dependent manner among patients with type 2 diabetes.

Pregnancy

If you're pregnant, it's best to be cautious when taking 10 Li M 500 Sr Tablet 10. Discuss this with your doctor before starting this medication.

Breastfeeding

Metformin is known to be excreted into human milk, while the effects of Teneligliptin on breastfed infants are unknown. If you're breastfeeding, consult your doctor before using this medicine.

Alcohol

Combining alcohol with this medicine could increase the risk of lactic acidosis, a serious medical condition. It's advised that you limit your alcohol intake while on this medication.

Liver

If you have liver issues, use 10 Li M 500 Sr Tablet 10 with caution. This medicine may affect liver function. Before starting, discuss your liver health with your doctor.

Kidney

This medicine is not used in patients with severe renal impairment. If you have kidney problems, it's important to consult your doctor before taking this medicine.

Using Machines & Driving

No specific precautions are necessary when driving or using machines while taking 10 Li M 500 Sr Tablet 10.

Allergy

If you know you're allergic to metformin, teneligliptin or any of the other ingredients in this medicine, avoid using 10 Li M 500 Sr Tablet 10.

Children

The safety and effectiveness of 10 Li M 500 Sr Tablet 10 for children have not been established. Always consult your doctor before giving this medicine to individuals under 18 years of age.

Older Patients

Older patients should take 10 Li M 500 Sr Tablet 10 under medical supervision, as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of 10 Li M 500 Sr Tablet 10

Drug-Drug Interactions

10 Li M 500 Sr Tablet 10 may interact with the following medicines:

CYP3A4 or P-gp inhibitors like ketoconazole or atazanavir may interact with 10 Li M 500 Sr Tablet 10, potentially increasing the plasma concentrations of teneligliptin.
Anticoagulants such as phenprocoumon or acenocoumarol may have reduced effects when taken with 10 Li M 500 Sr Tablet 10 due to metformin's influence.
Thyroid hormone supplements: Levothyroxine's effectiveness can be decreased by the presence of this medicine.
ACE Inhibitors like enalapril or lisinopril, when used with 10 Li M 500 Sr Tablet 10, can increase the hypoglycemic effect.

Drug-Food Interactions

None

Drug-Disease Interactions

10 Li M 500 Sr Tablet 10 can interact with the following diseases:

Renal Disease: Severe renal impairment can result in adverse reactions when this medicine is used.
Hepatic Impairment: This medicine should be used with caution in patients with liver disease.
Metabolic Acidosis: Patients diagnosed with metabolic acidosis, including diabetic ketoacidosis, should avoid using this medicine.

Daily Dose

It's crucial that you take your daily dose of 10 Li M 500 Sr Tablet 10 as prescribed by your doctor. Dosage may vary depending on individual factors such as your health condition and how you respond to the medicine. Always stick to the dosage recommended by your doctor, and never alter it without seeking medical advice.

Over Dose

In the case of an overdose, you might experience common side effects in a more pronounced way. However, it's always better not to panic and calmly inform your doctor about the situation. Remember, following the prescribed dosage helps prevent such situations.

Missed Dose

If you've missed a dose of 10 Li M 500 Sr Tablet 10, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Don't adjust your dosage or frequency without consulting your doctor.

Store 10 Li M 500 Sr Tablet 10 in a dry place below 30°C.
Shield it from light to maintain its effectiveness.
Keep this medicine unreachable for children, ensuring their safety.
Always check the expiration date before using the tablet.

Incorporate a balanced diet rich in fibre and low in simple sugars to help manage your blood sugar levels.
Regular physical activity like walking or yoga can also support glucose control, but always consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Biguanide Antihyperglycemic, DPP-4 Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is 10 Li M 500 Sr Tablet 10 used for?

This medicine is used to manage type 2 diabetes in adults when single therapy with either metformin or teneligliptin doesn't effectively control blood sugar.

How does 10 Li M 500 Sr Tablet 10 work?

Metformin in this tablet reduces glucose production in the liver, enhances glucose uptake and use, while teneligliptin increases insulin release and reduces glucagon secretion.

Can I take 10 Li M 500 Sr Tablet 10 during pregnancy?

It's best to consult your doctor. There aren't sufficient studies about its use during pregnancy, so it should be used only if clearly needed.

Is 10 Li M 500 Sr Tablet 10 safe for nursing mothers?

Metformin is known to pass into human milk, but the effect on a breastfed infant is unknown. Therefore, consult with your doctor before using this medicine on such occasions.

Can children take 10 Li M 500 Sr Tablet 10?

The safety and effectiveness of this medicine haven't been established for paediatric use. It's meant for adults and should be given to children only if prescribed by a doctor.

What happens if I overdose on 10 Li M 500 Sr Tablet 10?

Overdose can lead to serious conditions like lactic acidosis. Immediate medical attention is required in case of an overdose.

What should I do if I have severe joint pain after taking this medicine?

Severe and disabling joint pain can occur with DPP-4 inhibitors like teneligliptin. If you experience severe joint pain, consult your doctor.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

3RD FLOOR, SIDCO GARMENT COMPLEX GUINDY CHENNAI TAMIL NADU INDIA 600032

Country of origin: INDIA

References

Medlineplus. (n.d.). Metformin. Retrieved from https://medlineplus.gov/druginfo/meds/a696005.html
National Center for Biotechnology Information. (2013). Efficacy and safety of teneligliptin, a novel dipeptidyl peptidase-4 inhibitor, in Korean patients with type 2 diabetes mellitus: a 24-week multicentre, randomized, double-blind, placebo-controlled phase III trial. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650886/
U.S. Food and Drug Administration. (2006). FDA Approved Drug Products: Metformin Hydrochloride. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf
PubChem. (n.d.-aj). Metformin. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/metformin
PubChem. (n.d.-az). Teneligliptin. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Teneligliptin
Teneligliptin: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB11950

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