Acivir 400 Mg Tablet Dt 10

Acivir 400 Dt Tablet 10

Cipla Ltd.

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MRP ~~₹152.99~~

₹125.45

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Composition

Aciclovir / Acyclovir (400 Mg)

Acivir 400 Dt Tablet 10 is primarily used to treat viral infections caused by the herpes simplex virus and the varicella-zoster virus. This medication belongs to a class of medicines known as antivirals.

In addition to its primary use, it also helps manage conditions such as genital herpes, cold sores, chickenpox, and shingles. It alleviates symptoms and speeds up the healing process of sores.

Following your doctor's guidance on how and when to take this medication is important. Before starting Acivir 400 Dt Tablet 10, inform your doctor about any pre-existing conditions or medications you are taking. If you experience any side effects, notify your doctor immediately. To achieve the best results, continue taking the medicine for the full duration prescribed by your doctor.

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Acivir 400 Dt Tablet 10 is used for the following:

Management of herpes simplex virus infections, inclusive of genital herpes and cold sores
To control chickenpox, which is caused by the varicella-zoster virus, it is essential to follow prevention methods such as vaccination, practice good hygiene, and seek appropriate treatment if infected
Management of shingles, which is also known as herpes zoster and is caused by varicella-zoster virus
Management of herpes labialis, commonly referred to as cold sores

Directions for Use of Acivir 400 Dt Tablet 10

Here's how you should take Acivir 400 Dt Tablet 10:

Swallow the medicine by mouth with a glass of water.
Do not crush or chew the medicine.
Always stick to the prescribed dose.
Never take more than what your doctor has recommended.

Acivir 400 Dt Tablet 10 is taken orally.

Acivir 400 Dt Tablet 10 may lead to the following common side effects:

Headache
Dizziness
Nausea and vomiting
Diarrhoea
Fatigue
Fever
Stomach Pain
Red spots or bumps on your skin

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Acivir 400 Dt Tablet 10. However, if you experience any serious side effects or worsening symptoms, please consult your doctor.

Here are some suggestions for managing common side effects:

Nausea and Vomiting: Take Acivir 400 Dt Tablet 10 with meals to reduce this effect.
Stomach Pain: Consider taking the medicine after meals to ease this discomfort.

Acivir 400 Dt Tablet 10 contains aciclovir (400 mg), which has a specific mechanism of action:

Affinity for thymidine kinase: Aciclovir is selective for virus-infected cells due to its attraction towards an enzyme called thymidine kinase (TK). This enzyme is produced by the herpes simplex virus and the varicella zoster virus.
Inhibition of viral DNA synthesis: Once aciclovir enters the cell, cellular enzymes transform it into aciclovir triphosphate. This compound acts as a competitive inhibitor of viral DNA polymerase, stopping it from incorporating into the growing viral DNA chain and halting viral DNA replication.

Pregnancy

Caution is advised while taking Acivir 400 Dt Tablet 10 if you are pregnant. It is best to consult your doctor before starting this medication.

Breastfeeding

Breastfeeding mothers should take Acivir 400 Dt Tablet 10 with caution. Discuss the potential risks and benefits with your doctor.

Alcohol

There's no specific information about the interaction of Acivir 400 Dt Tablet 10 with alcohol. However, it's always a good idea to avoid or limit alcohol consumption while on any medication.

Liver

If you have liver problems, discussing them with your doctor before starting Acivir 400 Dt Tablet 10 is advised. This medicine may affect liver function.

Kidney

Caution is advised before using Acivir 400 Dt Tablet 10 if you have a history of any kidney problems. Consult your doctor before taking this medicine.

Using Machines & Driving

Acivir 400 Dt Tablet 10 may cause side effects like dizziness or tiredness which could affect your ability to drive or operate machinery. If you experience these or similar effects, avoid driving or operating machinery until you feel well again.

Allergy

If you're allergic to aciclovir or any other ingredients in Acivir 400 Dt Tablet 10, avoid using this medicine. Always inform your doctor about your allergies.

Children

Acivir 400 Dt Tablet 10 is an adult medication. Caution is advised while giving this medicine to children under 18. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should use Acivir 400 Dt Tablet 10 under medical supervision, as they may be more susceptible to side effects. This is especially important if they have liver or kidney issues or are taking other medications. Your doctor will provide guidance based on your health status.

Drug-Drug Interactions

Acivir 400 Dt Tablet 10 interacts with the following medicines:

Gout medications: Medicines like probenecid, used to manage gout, can interfere with the excretion of aciclovir, leading to higher blood levels of the medication.
Stomach ulcer medications: Cimetidine, used to manage stomach ulcers, may increase the blood levels of aciclovir by reducing its renal clearance.
Immunosuppressive medications: Mycophenolate mofetil, used post-organ transplantation and for Crohn's disease, when taken together with aciclovir, can lead to increased blood levels of both medications.

Drug-Food Interactions

The effects of Acivir 400 Dt Tablet 10 are not known to be influenced by any specific foods.

Drug-Disease Interactions

Acivir 400 Dt Tablet 10 interacts with the following diseases:

Renal impairment: If you have kidney problems, your body might be unable to properly eliminate aciclovir, leading to higher blood levels which can increase the risk of side effects.
Immunodeficiency: If your immune system is compromised due to a condition like HIV/AIDS or cancer treatment, you might have a slower response to aciclovir treatment.

Daily Dose

You should take Acivir 400 Dt Tablet 10 daily as per your doctor's prescription. The dosage might vary due to individual factors such as the condition's severity and your response to treatment. Always adhere to the prescribed dosage and consult your doctor before changing it.

Over Dose

If you unintentionally take more than the prescribed dose of Acivir 400 Dt Tablet 10, you may experience common side effects like headache, dizziness, or stomach pain in an increased manner. If these symptoms persist, inform your doctor.

Missed Dose

In case you miss a dose of Acivir 400 Dt Tablet 10, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and continue with your regular dosage schedule. Never adjust your dosage without consulting your doctor.

Store Acivir 400 Dt Tablet 10 at a temperature not exceeding 30°C.
Keep it in a dry place, shielded from light and moisture.
Make sure to keep this medicine out of reach of children and pets.
Remember to use the medicine before its expiriration date.

If you are managing herpes or chickenpox with Acivir 400 Dt Tablet 10, maintaining personal hygiene is crucial. Regular handwashing can help prevent the spread of these viruses.
For those with herpes, practising safe sex using barrier methods like condoms can help prevent transmission of the virus. It's recommended to abstain during an outbreak.

Fact Box

Drug Category	Viral DNA Synthesis Inhibitor
Therapeutic Category	Antiviral
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Genital Herpes, Cold Sores, Chickenpox

What is Acivir 400 Dt Tablet 10 used for?

Acivir 400 Dt Tablet 10 is an antiviral medicine used to manage viral infections caused by the herpes simplex virus and varicella zoster virus.

How does Acivir 400 Dt Tablet 10 work?

It contains aciclovir which stops the multiplication of the virus in human cells, inhibits viral DNA synthesis, helps clear infections, relieve symptoms, and reduce recurrences.

Can Acivir 400 Dt Tablet 10 be taken with or without food?

Yes, you can take Acivir 400 Dt Tablet 10 with or without food as instructed by your doctor. It should be dissolved in water before taking.

Who should use caution when taking Acivir 400 Dt Tablet 10?

Use it cautiously if you're pregnant or breastfeeding, elderly (over 65 years), or have kidney problems or immunodeficiency. Avoid it if you're allergic to aciclovir.

What are some common side effects of Acivir 400 Dt Tablet 10?

You may experience headaches, dizziness, nausea, vomiting, diarrhoea, fatigue, fever, stomach pain, skin rash, and sensitivity to light.

What precautions should I take while using Acivir 400 Dt Tablet 10?

Stay hydrated and get adequate rest during treatment. Also, ensure good hygiene to prevent the spread of infections like chickenpox and shingles.

Can other medications interact with Acivir 400 Dt Tablet 10?

Yes. It may interact with probenecid (for gout), cimetidine (for stomach ulcers), and mycophenolate mofetil (for Crohn's disease). Always inform your doctor about all the medicines you're taking.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

Acyclovir. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00787
Acyclovir: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a681045.html
Aciclovir: Medicine for cold sores, chickenpox, and shingles. (2022). NHS. https://www.nhs.uk/medicines/aciclovir/
ZOVIRAX® (acyclovir) Capsules ZOVIRAX® (acyclovir) Tablets ZOVIRAX® (acyclovir) Suspension PRESCRIBING INFORMATION. (2005, June). U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/018828s030%2C020089s019%2C019909s020lbl.pdf
About aciclovir. (2022). NHS. https://www.nhs.uk/medicines/aciclovir/about-aciclovir/
Acyclovir (ACV) uses and side effects | Children's Pittsburgh. (n.d.). Children's Hospital of Pittsburgh. https://www.chp.edu/our-services/transplant/liver/education/medications/aciclovir-zovirax

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