Acotrust Od 300 Mg Tablet 10

Acotrust Od Tablet 10

Dr. Reddys Laboratories Ltd

Strip of 10 Units

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MRP ~~₹423.50~~

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Composition

Acotiamide (300 Mg)

Acotrust OD Tablet is primarily used to manage functional dyspepsia, a chronic condition affecting the upper digestive tract. This medication belongs to a class known as prokinetic agents.

This medicine serves to regulate gut motility, reducing symptoms like post-meal fullness, difficulty in finishing a normal-sized meal, stomach pain and bloating. It provides relief from these discomforts that are characteristic of functional dyspepsia.

Before you start taking this medicine, consult your doctor who will advise you on the correct dosage and frequency. It's important to let your doctor know about any pre-existing medical conditions or ongoing medications. Always report any side effects that you notice while taking this medicine. Remember to continue taking the medication for the entire duration prescribed by your doctor for optimal benefits.

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Acotrust OD Tablet is used for the following:

Management of functional dyspepsia: This is a chronic digestive disorder that affects the upper part of your digestive tract.
Relief from postprandial fullness: This is when you feel uncomfortably full after eating a meal.
Reduction of early satiety: This symptom occurs when you can't finish a normal-sized meal because you feel full too quickly.
Alleviation of epigastric pain or burning: These are discomfort or burning sensations in the area located just below your ribs and above your belly button.
Relief from bloating: You may feel like your stomach is swollen or full of gas.

Directions for Use of Acotrust Od Tablet 10

Follow these instructions while taking Acotrust OD Tablet:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Always take this medicine in the morning before breakfast.
Do not stop taking this medicine without consulting your doctor.

Acotrust OD Tablet is taken orally.

Here are some common side effects that might occur while taking Acotrust OD Tablet:

Diarrhoea
Constipation
Nausea
Vomiting
Abdominal pain: This is discomfort or pain that you feel anywhere between your lower chest and groin.
Headache
Dizziness: You may feel lightheaded, as though you're going to faint.
Skin rash or pruritus: You might notice red, itchy spots on your skin.

Managing the Side Effects:

Most side effects are temporary and generally harmless, and they resolve when the use of Acotrust OD Tablet is discontinued. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage a couple of these common side effects:

Diarrhoea: Consider taking Acotrust OD Tablet with food to help manage this side effect.
Abdominal pain: If you experience stomach discomfort after taking the medicine, try having it with a meal.

Acotrust OD Tablet contains acotiamide (300 mg), which interacts with your body in the following ways:

Acetylcholinesterase Inhibition: Acotiamide prevents the breakdown of acetylcholine, a chemical messenger involved in movement of food in the gut. This leads to an increase in acetylcholine levels in the nervous system within the gut.
Enhanced Gut Motility: By increasing acetylcholine levels, acotiamide aids in promoting movement of food through your digestive system and speeding up stomach emptying.
Antagonistic Effects at M1 and M2 Receptors: Acotiamide also acts as an opponent at specific nerve cell receptors (M1 and M2 muscarinic receptors) in your gut. This helps improve how your gut moves food along.
Enhanced Neurotransmission at M3 and 5-HT4 Receptors: Acotiamide enhances signals at other specific nerve cell receptors (M3 receptor and 5-HT4 receptor) in your gut. The overall effect is better gut movement, reduced stomach accommodation, and relief from the discomforts of functional dyspepsia.

Pregnancy

Caution is advised while taking Acotrust OD Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

We don't know if Acotrust OD Tablet is passed into human milk. If you are breastfeeding, make sure to discuss this with your doctor before starting this medicine.

Alcohol

There is no known interaction between alcohol and Acotrust OD Tablet. However, it's always a good idea to limit alcohol consumption when taking any medicine.

Liver

If you have mild to moderate liver issues, this medicine can be taken with caution. However, if you suffer from severe liver disease, Acotrust OD Tablet is not recommended. Consult your doctor for advice.

Kidney

Caution is advised before using Acotrust OD Tablet if you have a history of kidney problems. It's smart to discuss any health concerns with your doctor before taking this medicine.

Using Machines & Driving

There is no information suggesting that the Acotrust OD Tablet affects one's ability to drive or operate machinery. However, if one feels dizzy after taking it, they should avoid these activities and speak to their doctor.

Allergy

Avoid using Acotrust OD Tablet if you are allergic to acotiamide or any other ingredients in the tablet.

Children

Acotrust OD Tablet should not be given to children or adolescents under 18 years of age due to insufficient data. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients can take Acotrust OD Tablet, but they should do so under medical supervision as they may be more susceptible to its effects. Doctors will guide older patients based on their health status, especially considering potential liver or kidney issues.

Drug-Drug Interactions

Acotrust OD Tablet interacts with the following medicines:

Strong CYP2D6 inhibitors: Medicines like paroxetine, fluoxetine, or quinidine may increase the levels of acotiamide in your body, leading to more pronounced effects or side effects.
Cholinergic agents: If you're taking medicines such as pilocarpine or donepezil alongside Acotrust OD Tablet, you may experience enhanced effects like slowed heart rate, low blood pressure, or stomach cramps.
Anticholinergic medicines: Medications like atropine, hyoscyamine, or dicyclomine may reduce the effectiveness of Acotrust OD Tablet by opposing its action on gut movement.

Drug-Food Interactions

No specific food interactions have been reported with Acotrust OD Tablet. However, it's always a good idea to maintain a balanced diet while on medication.

Drug-Disease Interactions

Acotrust OD Tablet interacts with the following diseases:

Severe liver disease: If you have severe liver damage, using this tablet might not be safe due to a lack of sufficient data on its use in such conditions.
Kidney disease: As acotiamide is excreted through urine, if you have kidney problems, your doctor will monitor your condition closely while you're on this medication.

Daily Dose

It's crucial to take the daily dose of Acotrust OD Tablet as your doctor directs. The amount may be adjusted based on your individual health and how you respond to the medicine. It's important to stick with the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

If you accidentally take too much of this medicine, you might experience symptoms such as vomiting, abdominal pain, or diarrhoea. It's important not to panic, but do inform your doctor about it.

Missed Dose

If you forget to take your Acotrust OD Tablet, take it as soon as you remember. But if it's almost time for the next dose, skip the one you missed and get back on track with your regular schedule. Do not take extra tablets without speaking with your doctor first.

Store your Acotrust OD Tablet at a cool, dry room temperature, not exceeding 30°C.
Keep the tablet out of direct sunlight and away from moisture.
Always keep this medicine out of reach of children.
Ensure you use the tablet before the expiry date printed on the product packaging.

To manage functional dyspepsia symptoms, try incorporating a fibre-rich diet, including whole grains, fruits and vegetables. Fibre aids in digestion and can help reduce bloating.
Regular physical activity can improve gut motility. Aim for at least 30 minutes of moderate exercise daily, such as brisk walking or cycling.

Fact Box

Drug Category	Prokinetic Agent
Therapeutic Category	Gastrointestinal Medication
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Functional Dyspepsia

What is Acotrust OD Tablet used for?

Acotrust OD Tablet is used to manage functional dyspepsia in adults, reducing symptoms like bloating and discomfort after meals.

How does Acotrust OD Tablet work?

It contains acotiamide, which increases the concentration of acetylcholine, enhancing gut movement and reducing dyspepsia symptoms.

Can I take Acotrust OD Tablet during pregnancy?

There's not enough data on its use during pregnancy. It should be avoided unless your doctor thinks the benefits outweigh the risks.

Is Acotrust OD Tablet safe for children?

No, the safety and effectiveness of this medicine in children and adolescents below 18 years haven't been established.

How should I take Acotrust OD Tablet?

Take one tablet orally with water before breakfast. The duration of treatment depends on how your body responds to it.

What adverse reactions may occur with Acotrust OD Tablet?

Common side effects include diarrhoea, constipation, nausea, vomiting, abdominal pain, headache, dizziness and skin rash. Serious adverse reactions are rare.

Can I take other medicines along with Acotrust OD Tablet?

Some medicines may interact with Acotrust OD Tablet, affecting how it works. Always consult your doctor before starting any new medicine.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Bigshare Services Pvt. Ltd. 306, Right Wing, 3rd Floor Amrutha Ville, Opp.Yash Hyderabad - 500082 Telangana

Country of origin: INDIA

References

Acotiamide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB12482
(n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098008/. Accessed on April 1, 2024.
PubChem. (n.d.-a). Acotiamide. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Acotiamide
Sinha, S. D., Sinha, S. K., Talluri, L., Bhashyakarla, R. K., Malladi, U., Dosi, R. V., Jain, M. K., Chary, S., Reddy, M., & Thakur, P. (2021). Efficacy and safety of orally administered acotiamide Extended-Release tablets among Functional Dyspepsia-Postprandial Distress Syndrome patients: a randomized, Double-Blind, Multicenter study. Curēus. https://doi.org/10.7759/cureus.14361

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