Adquin Oz 200500 Mg Tablet 10

Adquin-oz 200/500 MG Tablet 10

Advent Life Sciences Pvt Ltd

Pack of 10 Units

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Composition

Ofloxacin (200 Mg) + Ornidazole (500 Mg)

Adquin-oz 200/500 MG Tablet 10 is a combination of norfloxacin and tinidazole used to treat bacterial and parasitic infections, including urinary tract, respiratory, gastrointestinal, and sexually transmitted infections. It also treats conditions like dysentery, pelvic inflammatory disease, and is used as a surgical prophylactic agent.

Before you start taking this medicine, consult your doctor for accurate dosage and frequency based on your health condition and response to treatment. Also, inform your doctor about any pre-existing conditions or ongoing medications that you're currently taking. If you notice any side effects while you are on this medicine, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

Adquin-oz 200/500 MG Tablet 10 is a combination of two antibiotics used to treat a wide range of bacterial and parasitic infections. It is effective in managing infections in the urinary tract, kidneys, prostate, skin, soft tissues, bones, joints, and pelvic region. It also treats respiratory tract infections like pneumonia and bronchitis, ear, nose and throat infections, and sexually transmitted diseases like chancroid. Additionally, it is used for gastrointestinal infections, prophylaxis before surgery, and managing intra-abdominal infections such as peritonitis.

Directions for Use of Adquin-oz 200/500 MG Tablet 10

Follow these instructions while taking Adquin-oz 200/500 MG Tablet 10:

Swallow the tablet whole with a glass of water.
Ensure you do not crush or chew the tablet.
The tablets should be taken on an empty stomach, either 1 hour before or 2 hours after meals.
Do not stop taking this medicine without consulting your doctor first, even if symptoms improve earlier.

Adquin-oz 200/500 MG Tablet 10 is taken orally.

Side Effects of Adquin-oz 200/500 MG Tablet 10

Adquin-oz 200/500 MG Tablet 10 may cause the following side effects:

Nausea
Vomiting
Diarrhoea
Abdominal pain
Difficulty falling asleep
Mild skin rash

Managing the Side Effects:

Most side effects are temporary and generally harmless, and they resolve when the use of Adquin-oz 200/500 MG Tablet 10 is discontinued. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

How Adquin-oz 200/500 MG Tablet 10 Works?

Adquin-oz 200/500 MG Tablet 10 contains two active ingredients:

Ofloxacin (200 mg): This belongs to the fluoroquinolone class of antibiotics. It works by inhibiting certain enzymes in bacteria called DNA gyrase and topoisomerase IV, which are required for DNA replication, transcription, repair and recombination. By interfering with these processes, it leads to bacterial cell death.
Ornidazole (500 mg): A nitroimidazole antibiotic and antiprotozoal agent, ornidazole disrupts the DNA structure in susceptible organisms, leading to cell death in anaerobic bacteria and protozoa.

Together, these components provide broad-spectrum activity against aerobic and anaerobic bacteria and certain protozoan parasites. They work synergistically to enhance the efficacy of this medicine.

Pregnancy

Adquin-oz 200/500 MG Tablet 10 is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Adquin-oz 200/500 MG Tablet 10 is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Alcohol should be strictly avoided while taking Adquin-oz 200/500 MG Tablet 10 and for 48 hours after the last dose due to the potential disulfiram-like reaction with ornidazole, which can cause severe nausea, vomiting, sweating, headache, palpitations, and chest pain.

Liver

Caution is advised while taking Adquin-oz 200/500 MG Tablet 10 in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Adquin-oz 200/500 MG Tablet 10. This medicine may affect liver function.

Kidney

Caution is advised before using Adquin-oz 200/500 MG Tablet 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Adquin-oz 200/500 MG Tablet 10 may cause dizziness or fatigue. Caution is advised while driving or operating machinery until you know how the medication affects you.

Allergy

This medicine is contraindicated for those with a known hypersensitivity to quinolones, nitroimidazoles, or any components of the formulation. If you have a history of allergies, discuss them with your doctor before starting on Adquin-oz 200/500 MG Tablet 10.

Children

Caution is advised while giving Adquin-oz 200/500 MG Tablet 10 to anyone under 18 years of age. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Adquin-oz 200/500 MG Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Interactions of Adquin-oz 200/500 MG Tablet 10

Drug-Drug Interactions

Adquin-oz 200/500 MG Tablet 10 may interact with the following medicines:

Alpha-2 adrenergic receptor agonists: The combination of molecules in this medicine could lead to increased levels of alpha-2 adrenergic receptor agonists tizanidine in your blood, potentially causing undesirable effects like low blood pressure or sedation.
Xanthines: Using both medications might increase levels of xanthines like theophylline, risking side effects such as rapid heart rate and seizures.
Blood thinners like warfarin, when taken along with this medicine, could enhance the anticoagulant effect of warfarin, raising the risk of bleeding complications.
Cyclosporine: A combination of both medications may raise cyclosporine levels, leading to kidney problems.
Tricyclic antidepressants taken along with this medication could risk the possibility of increasing side effects like dizziness and confusion.
NSAIDs used together with this medication might heighten the risk of seizures or convulsions.

Drug-Food Interactions

Certain food items can interfere with Adquin-oz 200/500 MG Tablet 10. Those include:

Dairy products: Foods rich in calcium, like milk or yoghurt, may decrease the absorption of ofloxacin.

Drug-Disease Interactions

Adquin-oz 200/500 MG Tablet 10 can interact with the following diseases:

Epilepsy: This medicine could potentially trigger seizures or fits.
G6PD enzyme deficiency: People with this condition may be at risk of developing haemolytic anaemia (breakdown of red blood cells) while taking this medication.
Severe renal impairment: In patients with severe kidney disease, there's a potential for accumulation of ornidazole, thereby increasing the risk of side effects.
Myasthenia gravis: This condition could worsen with the use of this medicine due to its neuromuscular blocking activity.

Dosage of Adquin-oz 200/500 MG Tablet 10

Daily Dose

Always take the daily dose of Adquin-oz 200/500 MG Tablet 10 as suggested by your doctor. Your doctor may adjust the dosage based on factors like your health condition and response to the medicine. Always stick to the prescribed dosage and never alter it without seeking your doctor's advice.

Over Dose

If you accidentally take more than the recommended dose, you might experience more intense common side effects like nausea, dizziness, and headache. If these symptoms persist or worsen, do inform your doctor.

Missed Dose

If you forget to take your regular dose of Adquin-oz 200/500 MG Tablet 10, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store your Adquin-oz 200/500 MG Tablet 10 at room temperature, between 15-30°C.
Protect it from light and moisture to maintain its effectiveness.
Always keep this medicine out of reach of children.
Remember to use it before the expiry date mentioned on the packaging.

If you're taking Adquin-oz 200/500 MG Tablet 10 for urinary tract infections, increase your intake of water and other fluids. This helps flush bacteria out of your system quicker.
If you are using it for gastrointestinal infections, maintain good food hygiene. Make sure to wash your hands before eating and thoroughly clean fruits and vegetables. This can help prevent further bacterial or parasitic infections.

Fact Box

Drug Category	DNA synthesis inhibitor
Therapeutic Category	Antibacterial and Antiprotozoal
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Urinary tract infections, Gynaecological infections, Respiratory tract infections

What is Adquin-oz 200/500 MG Tablet 10 used for?

Adquin-oz 200/500 MG Tablet 10 contains two medicines: Norfloxacin and Tinidazole. It is used to treat diarrhea and dysentery caused by infections. These medicines work by killing the harmful germs that cause the infection.

How does Adquin-oz 200/500 MG Tablet 10 work?

It contains ofloxacin and ornidazole that stop the growth of harmful bacteria and parasites causing infection.

Can I take Adquin-oz 200/500 MG Tablet 10 during pregnancy or while breastfeeding?

It is not advisable to take this medication during pregnancy or breastfeeding due to potential risks. Always consult your doctor before taking this medicine if you are pregnant or breastfeeding.

When will I start feeling better after taking Adquin-oz 200/500 MG Tablet 10?

Symptoms may improve within 2-3 days, but always complete the full course prescribed by your doctor.

What should I do if I miss a dose of Adquin-oz 200/500 MG Tablet 10?

Take the missed dose as soon as you remember, but never double the dose to make up for a missed one.

Is it safe to consume alcohol while taking Adquin-oz 200/500 MG Tablet 10?

No, alcohol should be avoided as it can cause severe side effects like nausea and vomiting.

Can Adquin-oz 200/500 MG Tablet 10 lead to addiction?

No, this medicine does not cause addiction or dependence, but misuse can lead to antibiotic resistance.

Last Updated On 19 Dec. 2024 | 1:15PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

A1/2, Shriramkunj Complex Takli Road Nashik Mh In 422011

Country of origin: INDIA

References

MedlinePlus. (2024). Ofloxacin: MedlinePlus Drug Information. Retrieved from https://medlineplus.gov/druginfo/meds/a691005.html
U.S. Food and Drug Administration. (2007). FLOXIN® (ofloxacin tablets) Tablets, 200 mg, 300 mg, 400 mg. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/019735s057lbl.pdf
U.S. Food and Drug Administration. (n.d.). Ofloxacin. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/psg/PSG_021618.pdf
Ornidazole: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB13026
PubChem. (n.d.). Ornidazole. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Ornidazole

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