Ambristar 5 Mg Tablet 10

Ambristar 5 Tablet 10

Steris Healthcare

Strip of 10 Units

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MRP ~~₹1550~~

₹774.04

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Composition

Ambrisentan (5 Mg)

Strength:

5 MG 10 MG

Ambristar 5 Tablet is primarily used to manage pulmonary arterial hypertension (PAH), a condition that causes high blood pressure in the arteries of the lungs. This medicine belongs to a group known as endothelin receptor antagonists.

Apart from its main use, this medicine also significantly enhances the quality of life for those with PAH. It aids in making daily activities easier, improves exercise ability, and helps delay the progression of the disease.

Before you start taking this medicine, it's important to consult your doctor for the appropriate dosage and frequency. Make sure to inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Ambristar 5 Tablet is used for the following:

Managing Pulmonary Arterial Hypertension (PAH): This condition involves high blood pressure in the arteries that carry blood from your heart to your lungs.
Enhancing quality of life: By managing PAH, this medicine makes it easier to perform daily activities.
Improving exercise ability: The tablet helps increase physical performance by reducing symptoms of PAH.
Slowing down the progression of PAH: Regular use can delay the worsening of the disease.

Directions for Use of Ambristar 5 Tablet 10

Here's how you should take Ambristar 5 Tablet:

Swallow the tablet whole with a glass of water. Do not crush or chew it.
Follow your doctor's instructions for dosage and frequency. Do not alter the prescribed dose on your own.
Remember, it's important not to discontinue this medicine without consulting your doctor first.

Ambristar 5 Tablet is taken orally.

Ambristar 5 Tablet may have the following common side effects:

Headache
Dizziness
Nasal congestion
Sinusitis: This refers to inflammation or swelling of the tissue lining the sinuses, often resulting in a blocked nose, facial pain, and a reduced sense of smell.
Flushing
Nausea
Fatigue
Swelling of the hands, feet, or ankle

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Ambristar 5 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Fatigue: Consider taking this medicine at night if it causes you to feel tired during the day.
Nausea: Try taking Ambristar 5 Tablet with food or milk to lessen this effect.

Ambristar 5 Tablet contains Ambrisentan (5 mg). This ingredient works in the body as follows:

Blockage of Endothelin Action: Ambrisentan works by preventing the action of endothelin, a substance that narrows the blood vessels and increases blood pressure in the lungs.
Reduction of Pulmonary Arterial Pressure: By blocking the action of endothelin, Ambrisentan effectively relaxes and widens the blood vessels, reducing the pressure in the pulmonary arteries.

Pregnancy

Ambristar 5 Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, it's crucial to discuss this with your doctor before starting this medicine.

Breastfeeding

Ambristar 5 Tablet is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

There isn't enough information available regarding the interaction of Ambristar 5 Tablet with alcohol. However, caution is advised. It's best to consult your doctor before consuming alcohol while taking this medicine.

Liver

Caution is advised while taking Ambristar 5 Tablet if you have liver problems. This medicine may affect liver function and should not be used in case of severe liver diseases. Discuss this with your doctor before starting the medication.

Kidney

If you have a history of kidney problems, caution is advised before using Ambristar 5 Tablet. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Ambristar 5 Tablet may cause dizziness or fatigue, which could impact your ability to drive or operate machinery. Caution is advised in such situations.

Allergy

Those who are allergic to ambrisentan or any of the components of Ambristar 5 Tablet should avoid using this medication. Make sure to inform your doctor about any allergies you have.

Children

Caution is advised while giving Ambristar 5 Tablet to individuals under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Ambristar 5 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Ambristar 5 Tablet interacts with the following medicines:

Immunosuppressants: Medicines like ciclosporin may interact with Ambristar 5 Tablet, leading to increased levels of Ambrisentan in the body and potential for more side effects.
Anti-tuberculosis Medicines: Concurrent use of medicines like rifampicin can potentially affect the effectiveness of Ambristar 5 Tablet.

Drug-Food Interactions

Drug-Disease Interactions

Ambristar 5 Tablet interacts with the following diseases:

Liver Disease: Individuals with severe liver problems should avoid using this medicine as it might exacerbate their condition.

Daily Dose

The daily dose of Ambristar 5 Tablet should be as directed by your doctor. It's essential to adhere to the prescribed dosage and not alter it without consulting your doctor.

Over Dose

Exceeding the prescribed dosage may lead to common side effects like headache, dizziness, and fatigue. If you've taken too much, inform your doctor about the situation.

Missed Dose

If you forget to take Ambristar 5 Tablet, do so as soon as you remember. If your next dose is due soon, skip the missed tablet and continue with your routine.

Ambristar 5 Tablet should be stored in a cool and dry place, ideally at room temperature, not exceeding 30°C.
Avoid exposing the medicine to excessive light, heat, or moisture.
Ensure the medicine is kept out of reach of children.
Check the expiry date on the pack, and do not use any tablets that are past this date.

Since pulmonary arterial hypertension (PAH) is managed by Ambristar 5 Tablet, it's beneficial to maintain a low-sodium diet. Excessive salt can raise blood pressure and worsen your condition.
Regular, moderate physical activity, tailored to your ability and comfort level, can help manage PAH symptoms. However, consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Endothelin Receptor Antagonist
Therapeutic Category	Anti-hypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Pulmonary Arterial Hypertension

Why is Ambristar 5 Tablet prescribed to me?

Ambristar 5 Tablet is prescribed to manage pulmonary arterial hypertension, a condition where the blood pressure in your lungs' arteries is high.

How does Ambristar 5 Tablet work in my body?

This medicine contains ambrisentan, which blocks the action of endothelin, a substance that narrows blood vessels, hence reducing pressure in your lung arteries.

Can I take this medicine while being pregnant?

No, you should not take Ambristar 5 Tablet while pregnant, as it can harm the fetus. Always use reliable contraception during its usage.

What do I do if I experience side effects?

If you notice side effects like headache, fatigue, or swelling in hands and feet, inform your doctor immediately.

Can I take other medicines along with Ambristar 5 Tablet?

Always inform your doctor about any other medicines you are taking, as Ambristar 5 Tablet can interact with some medications, potentially causing adverse effects.

How should I store Ambristar 5 Tablet?

Keep the medicine in a cool, dry place away from sunlight and keep it out of reach of children.

For how long do I need to take this medicine?

The duration of using Ambristar 5 Tablet depends on your individual health condition and response to therapy. Always follow your doctor's instructions.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Tanaji Chowk, Ambedkar Nagar, Kurla West, Kurla, Mumbai, Maharashtra 400070

Country of origin: INDIA

References

Gilead Sciences, Inc. (2018). Highlights of prescribing information [Prescribing information]. In Letairis. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/022081s040lbl.pdf
PHA’s Scientific Leadership Council. (2013). Ambrisentan (Letairis®). https://phassociation.org/wp-content/uploads/2018/04/Patients-Treatment-Ambrisentan-4-12-18.pdf
PubChem. (n.d.). Ambrisentan. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Letairis
Ambrisentan: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06403
Oudiz, R. J., Galiè, N., Olschewski, H., Torres, F., Frost, A., Ghofrani, H. A., Badesch, D. B., McGoon, M. D., McLaughlin, V. V., Roecker, E. B., Harrison, B. C., Despain, D., Dufton, C., & Rubin, L. J. (2009). Long-Term ambrisentan therapy for the treatment of pulmonary arterial hypertension. Journal of the American College of Cardiology, 54(21), 1971–1981. https://doi.org/10.1016/j.jacc.2009.07.033

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