Amifru Plus 105 Mg Tablet 10

Amifru Plus Tablet 10

Torrent Pharmaceuticals Ltd.

Strip of 10 Units

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MRP ~~₹96.00~~

₹76.80

₹9.60/Units

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Composition

Amiloride (5 Mg) + Torsemide (10 Mg)

Amifru Plus Tablet is primarily used for managing hypertension (high blood pressure) and edema (fluid retention). It's a combination medicine belonging to the class of diuretics.

This medicine is also used to control edema related to various conditions, such as congestive heart failure, liver disease, and kidney disorders. This makes the medicine versatile in managing fluid retention situations.

You need to take this medicine as directed by your doctor. Before starting on this medication, inform your doctor about any pre-existing medical conditions or ongoing medications. If you experience any side effects while on this medication, notify your doctor immediately. Be sure to continue taking the medicine for the duration prescribed by your doctor for optimal results.

Amifru Plus Tablet is used for managing the following conditions:

High blood pressure or hypertension
Fluid retention or oedema linked with congestive heart failure
Fluid accumulation associated with liver cirrhosis
Edema resulting from chronic kidney disease

Directions for Use of Amifru Plus Tablet 10

Follow these steps while taking Amifru Plus Tablet:

Take the medicine whole with a glass of water.
Avoid crushing or chewing the tablet.
The medicine can be taken with or without food.
Do not stop taking the medicine without consulting your doctor first.

Amifru Plus Tablet is taken orally.

Amifru Plus Tablet may have the following common side effects:

Dizziness
Fatigue
Nausea and vomiting
Diarrhoea or constipation
Muscle cramps: This is an involuntary and sudden contraction of your muscles.
Dry mouth
Electrolyte imbalances: These include hyponatremia, which is low blood sodium levels, and hypokalemia, which means low blood potassium levels.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Amifru Plus Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea and vomiting: You can try taking Amifru Plus Tablet with food to lessen this effect.
Diarrhoea or constipation: If you experience these side effects, consider taking this medicine after meals.

Amifru Plus Tablet is a combination medication, with each of its components contributing to its overall effects. The tablet consists of:

Amiloride (5 mg): This component is a potassium-sparing diuretic that functions by blocking sodium channels in your kidneys' distal tubules. This blocking reduces sodium reabsorption and increases potassium retention, leading to more urine output and decreased fluid retention.
Torsemide (10 mg): Torsemide is a loop diuretic that acts on a certain part of your kidneys known as the ascending limb of the loop of Henle. Here, it inhibits a transporter responsible for reabsorbing sodium, potassium, and chloride, leading to increased urine production.

Pregnancy

Caution is advised while taking Amifru Plus Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Pregnant and breastfeeding women should use Amifru Plus Tablet only if the potential benefits outweigh the risks. It's a good idea to discuss this with your doctor.

Alcohol

There is no specific information about the interaction of Amifru Plus Tablet with alcohol. However, it's always wise to avoid alcohol while on medication. Please consult your doctor for more details.

Liver

Caution is advised while taking Amifru Plus Tablet in case of liver disease. Discuss your medical history with your doctor before starting this medicine.

Kidney

Amifru Plus Tablet should be used with caution if you have kidney problems. Your doctor will adjust the dosage based on creatinine clearance.

Using Machines & Driving

While using Amifru Plus Tablet, if you experience dizziness or fatigue, avoid driving or operating heavy machinery until you feel better.

Allergy

If you are allergic to amiloride or torsemide, or any other components of this medicine, do not take Amifru Plus Tablet. A severe allergic reaction may occur.

Children

Amifru Plus Tablet is meant for adult use. Do not give this medicine to children without consulting a doctor.

Older Patients

Elderly patients should take Amifru Plus Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age as they might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Amifru Plus Tablet interacts with the following medicines:

Diuretics: The combination of Amifru Plus Tablet with other diuretics like furosemide or hydrochlorothiazide may amplify the diuretic and anti-hypertensive effects.
ACE inhibitors and angiotensin receptor blockers: Medicines such as enalapril, lisinopril, or losartan may interact with Amifru Plus Tablet, raising the risk of high potassium levels in your blood (hyperkalaemia).
NSAIDs: When taken together with Amifru Plus Tablet, NSAIDs like ibuprofen and naproxen can diminish the diuretic and blood pressure-lowering effects of the tablet.

Drug-Food Interactions

No specific food interactions have been reported for Amifru Plus Tablet.

Drug-Disease Interactions

Amifru Plus Tablet interacts with the following diseases:

Kidney Disease: Patients with kidney disease should exercise caution as Amifru Plus Tablet could exacerbate their condition.
Liver Disease: Those suffering from liver disease need to be careful while using this medicine as it could potentially worsen their condition.
Diabetes: As Amifru Plus Tablet could impact blood sugar control, diabetic patients need to monitor glucose levels closely when on this medicine.
Gout: Individuals diagnosed with gout might witness an increase in uric acid levels due to this medication.

Daily Dose

The daily dosage of Amifru Plus Tablet should be taken as directed by your doctor. This may vary based on factors such as your condition's severity and your response to the medication. It's crucial not to exceed the prescribed dosage without consulting your doctor. For further details regarding the dosage, refer to the package insert.

Over Dose

Accidentally taking more than the prescribed dosage of Amifru Plus Tablet may lead to common symptoms such as dizziness, headache, or muscle cramps. If you experience these or any other unusual symptoms, it's advisable to inform your doctor.

Missed Dose

If you forget to take a dose of Amifru Plus Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Increasing your dosage without consulting your doctor isn't recommended.

Store Amifru Plus Tablet at the ideal storage temperature below 30°C.
Retain the tablets in their original packaging until usage.
Keep this medication out of reach of children.
Always check the expiry date and do not use the tablet past this date.

If you're managing hypertension with Amifru Plus Tablet, consider reducing your salt intake. A diet low in sodium can help control high blood pressure.
For those dealing with oedema, try to reduce excessive fluid intake. This can help lessen fluid retention, aiding in managing symptoms associated with conditions like congestive heart failure or liver disease. Always consult your doctor for personalised advice.

Fact Box

Drug Category	Potassium-Sparing Diuretic, Loop Diuretic
Therapeutic Category	Antihypertensive, Diuretic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Congestive Heart Failure Edema, Liver Cirrhosis Edema, Chronic Kidney Disease Oedema

What is Amifru Plus Tablet used for?

Amifru Plus Tablet is used to manage hypertension (high blood pressure) and edema (swelling due to fluid accumulation) associated with heart failure, liver disease, and kidney disorders.

How does Amifru Plus Tablet work?

The medicine combines two diuretics, amiloride and torsemide, which work in the kidneys to reduce sodium reabsorption and increase urine output, thus reducing fluid retention and lowering blood pressure.

Can I take Amifru Plus Tablet during pregnancy?

The safety of taking Amifru Plus Tablet during pregnancy is not established. It should be used only if the potential benefits justify the risks, after consulting your doctor.

Are there any side effects of Amifru Plus Tablet?

Common side effects include dizziness, headache, fatigue, nausea, vomiting, diarrhoea or constipation, muscle cramps, dry mouth and electrolyte imbalances. Seek medical attention for severe or persistent side effects.

Can I stop taking Amifru Plus Tablet if my blood pressure is under control?

Do not stop taking Amifru Plus Tablet without consulting your doctor as it may lead to rebound hypertension and worsen edema. A gradual dose reduction under medical supervision is recommended when stopping treatment.

Can Amifru Plus Tablet cause electrolyte imbalances?

Yes, Amifru Plus Tablet may cause electrolyte imbalances like hyponatremia (low blood sodium) and hypokalemia (low blood potassium). Regular monitoring of electrolyte levels during treatment is recommended.

How long does it take for Amifru Plus Tablet to start working?

Diuretic effects of Amifru Plus Tablet are usually observed within 1-2 hours of administration; however, full therapeutic effect on blood pressure and edema may take several days to weeks.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Torrent House, Off. Ashram Road, Ahmedabad - 380009, Gujarat, India

Country of origin: INDIA

References

DailyMed - AMILORIDE HYDROCHLORIDE tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e0cc2d44-436a-47e8-a890-589882fff4c4
Amiloride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00594
Torasemide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00214
Torsemide: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a601212.html

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