Amika M 250 MG Injection 2 ML

Reltic Labs

Pack of 2 ML

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MRP ~~₹45~~

₹36

₹22.5/ML

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Composition

Amikacin (250 Mg)

Amika M 250 MG Injection 2 ML is primarily used to manage severe bacterial infections. It is an antibiotic medication belonging to the class of aminoglycosides.

It also helps manage pneumonia, urinary tract infections, bone and joint infections, septicemia (infections of the blood), brain and meninges infections, intra-abdominal infections, and skin and soft tissue infections, including infected burns. The medicine is also used prophylactically in high-risk hospitalised patients to prevent infections.

Before starting on this medication, consult your doctor, who will determine the appropriate dosage and frequency for you based on your medical condition. If you have any pre-existing diseases or are taking other medications, inform your doctor about them as well. Any side effects experienced during the course of this medication should be reported to your doctor immediately. You must continue taking this medicine for the duration prescribed by your doctor for optimal results.

Amika M 250 MG Injection 2 ML is used for the following conditions:

Managing severe respiratory tract infections, including pneumonia
Controlling urinary tract infections
Managing bone and joint infections
Controlling infections of the blood, also known as septicemia
Treating infections of the brain and meninges
Managing intra-abdominal infections
Treating skin and soft tissue infections
Preventing infections in patients who are hospitalised and at high risk

Directions for Use of Amika M 250 MG Injection 2 ML

A healthcare professional should administer this medication under the direct supervision of a doctor.

Amika M 250 MG Injection 2 ML is administered intramuscularly or by slow intravenous infusion.

Side Effects of Amika M 250 MG Injection 2 ML

Amika M 250 MG Injection 2 ML may cause the following side effects:

Local injection site reactions: This could include redness, swelling or pain at the injection site.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Amika M 250 MG Injection 2 ML. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. You might find relief from local injection site reactions by placing a cool compress on the affected area.

How Amika M 250 MG Injection 2 ML Works?

Amika M 250 MG Injection 2 ML contains amikacin (250 mg). The activity of this medicine can be described as follows:

Inhibition of Bacterial Protein Synthesis: Amikacin irreversibly binds to the 30S ribosomal subunit in susceptible bacteria. This interferes with the initiation complex and misreads mRNA, producing faulty peptide.
Bactericidal Action: By producing non-functional peptides, amikacin disrupts normal bacterial cell functions, ultimately leading to cell death. This makes it effective against a wide range of gram-negative and some gram-positive bacteria.

Pregnancy

Be cautious while taking Amika M 250 MG Injection 2 ML if you are pregnant. It's wise to consult your doctor before using this medicine. The benefits and risks need to be discussed.

Breastfeeding

Amikacin, the active ingredient in Amika M 250 MG Injection 2 ML, may pass into breast milk. If you're breastfeeding, it's advisable to consult your doctor before using this medicine.

Alcohol

There is no known interaction with alcohol for Amika M 250 MG Injection 2 ML. However, excessive drinking can impair your body's ability to recover from an infection. If you regularly drink alcohol, please consult your doctor.

Liver

Amika M 250 MG Injection 2 ML should be used with caution in patients with liver problems. Consult your liver health status with your doctor before starting this medicine.

Kidney

Amika M 250 MG Injection 2 ML needs careful management in patients with kidney problems since the medicine is cleared by the kidneys. It’s important to consult your doctor about your kidney health before using this medicine.

Using Machines & Driving

There are no specific precautions regarding driving or operating heavy machinery while on Amika M 250 MG Injection 2 ML. However, if you experience side effects like dizziness or impaired hearing, be cautious while driving or operating machines. Consulting your doctor beforehand is a wise step.

Allergy

If you have a known allergy to amikacin or any other aminoglycoside antibiotic, do not use Amika M 250 MG Injection 2 ML. Always inform your doctor about all known allergies before starting any new medication.

Children

Amika M 250 MG Injection 2 ML is meant for adults and should not be used in children unless specifically recommended by a doctor. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients may require close monitoring while on Amika M 250 MG Injection 2 ML due to potential kidney or liver issues or other ongoing medication. Your doctor will guide you based on your health status.

Interactions of Amika M 250 MG Injection 2 ML

Drug-Drug Interactions

Amika M 250 MG Injection 2 ML interacts with the following medicines:

Neurotoxic or Nephrotoxic Agents: Medicines like cisplatin, vancomycin, polymyxin B, or other aminoglycosides may increase the risk of kidney damage and hearing disorders when taken with Amika M 250 MG Injection 2 ML.
Potent diuretics: If you're on strong water pills like furosemide, be careful, as it may enhance the negative effects on your hearing caused by this medicine.
Beta-lactam antibiotics: The bacteria-killing effect of antibiotics such as penicillin or cephalosporins can be reduced when used alongside Amika M 250 MG Injection 2 ML.

Drug-Food Interactions

There are no known specific food or beverage interactions with Amika M 250 MG Injection 2 ML.

Drug-Disease Interactions

Amika M 250 MG Injection 2 ML interacts with the following diseases:

Renal impairment: If you have kidney problems, this medicine could worsen your condition.
Vestibular or Hearing disorders: For those already struggling with balance disorders or hearing issues, taking this medication might heighten these problems.
Neuromuscular disorders: If you're living with conditions like myasthenia gravis or Parkinson's disease, Amika M 250 MG Injection 2 ML could potentially exacerbate your symptoms.

Daily Dose

The recommended dose of Amika M 250 MG Injection 2 ML should be administered as prescribed by your doctor, based on factors like your health condition and response to the medicine.

Over Dose

Overdosage of this injection is unlikely as a healthcare professional administers it. However, consult your doctor if you experience side effects like dizziness and ringing in the ears.

Missed Dose

If you miss a dose of Amika M 250 MG Injection 2 ML, administer it as soon as you remember. However, never adjust your dosage without consulting your doctor.

Store Amika M 250 MG Injection 2 ML at a controlled temperature.
Protect it from light exposure and keep it in the original package until use.
Always keep this medicine out of the reach and sight of children.
Ensure you use the product before its expiration date.

If you are managing a urinary tract infection, drink plenty of water to help your body flush out bacteria.
For respiratory tract infections, avoid exposure to smoke and pollutants, as they can exacerbate symptoms.

Fact Box

Drug Category	Antibiotic
Therapeutic Category	Antibacterial
Available Dosage Types	Injection
Habit Forming	No
Ailment	Pneumonia, Urinary Tract Infections, Septicemia

What is Amika M 250 MG Injection 2 ML used for?

Amika M 250 MG Injection 2 ML is used to manage severe bacterial infections such as pneumonia, urinary tract infections, and infections of the blood.

How does Amika M 250 MG Injection 2 ML work?

It contains amikacin, which stops the bacteria from making proteins they need to survive, resulting in their death and the infection being managed.

What should I do if I have kidney problems and need to take Amika M 250 MG Injection 2 ML?

You must consult your doctor before taking this medicine. Due to your kidney condition, it may be necessary to adjust the dosage or extend the timing between doses.

Is Amika M 250 MG Injection 2 ML safe for pregnant women?

Amika M 250 MG Injection 2 ML should only be used during pregnancy if a doctor determines that the benefits outweigh the potential risks. Always consult your doctor first.

Can I take other medicines while using Amika M 250 MG Injection 2 ML?

Some medicines may interact with Amika M 250 MG Injection 2 ML, causing adverse effects. Always inform your doctor about all other medicines you are currently taking.

What side effects can occur with Amika M 250 MG Injection 2 ML?

Common side effects include kidney damage, hearing loss, balance disorders, muscle weakness, allergic reactions and local injection site reactions. Consult your doctor before use.

How should I store my Amika M 250 MG Injection 2 ML?

Store it at room temperature, away from light, and out of the reach of children. Discard any discoloured or cloudy solutions. Please consult with your doctor for the best advice.

Last Updated On 01 Feb. 2024 | 7:27AM (IST)

Certified Content

Written by

Dr. Pauravi Abad

Medical Writer & Reviewer | 5 years

MBBS

Reviewed by

Dr. Snigdha Sharma

Clinical Health & Medical Reviewer | 7 years

MBBS

Check out Editorial Policy

Manufacturer details

SCO 40, 1st Floor, Sector 11, Panchkula, Haryana

References

U.S. National Library of Medicine. (2021). DailyMed - AMIKACIN SULFATE injection, solution. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=0b56f6df-a05d-4520-8bf0-d7cefe20f6ad
Mrowczynski, O. D., Langan, S. T., & Rizk, E. B. (2018). Intra-cerebrospinal fluid antibiotics to treat central nervous system infections: A review and update. Clinical Neurology and Neurosurgery, 170, 140–158. https://doi.org/10.1016/j.clineuro.2018.05.007
Logre, E., Enser, M., Tanaka, S., Dubert, M., Claudinon, A., Grall, N., Mentec, H., Montravers, P., & Pajot, O. (2020). Amikacin pharmacokinetic/pharmacodynamic in intensive care unit: a prospective database. Annals of Intensive Care, 10(1). https://doi.org/10.1186/s13613-020-00685-5
Ehrmann, S., Barbier, F., Demiselle, J., Quenot, J., Herbrecht, J., Roux, D., Lacherade, J., Landais, M., Seguin, E. (2023). Inhaled Amikacin to prevent Ventilator-Associated pneumonia. New England Journal of Medicine, 389(22), 2052–2062. https://doi.org/10.1056/nejmoa2310307

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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