Amlosafe Mt 50 Tablet 10

Aristo Pharmaceuticals Pvt.ltd

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Composition

Amlodipine (5 Mg) + Metoprolol Succinate (50 Mg)

Amlosafe MT 50 Tablet is primarily utilised to manage high blood pressure, also known as hypertension. This medication is a combination of two key active ingredients and belongs to the class of antihypertensive medicines.

In addition to managing hypertension, this medicine also provides relief in cases of chronic stable angina and vasospastic angina. Angina is a type of chest pain caused by reduced blood flow to the heart. The dual-component nature of this medicine addresses both these conditions effectively.

Before you start taking this medicine, it's important to consult your doctor for appropriate dosage and frequency. Make sure you inform them about any pre-existing conditions or ongoing medications to avoid potential interactions. If you experience any side effects while on this medication, notify your doctor immediately. To achieve the best results, continue taking the medicine for the full duration prescribed by your doctor.

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Amlosafe MT 50 Tablet is used in:

High blood pressure (hypertension): This medicine helps to lower and control high blood pressure, reducing the strain on the heart and preventing potential complications.
Heart-related chest pain (angina pectoris): It can relieve chest pain associated with angina by improving blood flow to the heart muscle, reducing its workload and oxygen demand.

Directions for Use of Amlosafe Mt 50 Tablet 10

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet, as it can impact the effectiveness of the medicine.
The tablet can be taken with or without food, but try to take it at the same time each day to get the most benefit.
Always follow your doctor's instructions about how and when to take this medicine.

Amlosafe MT 50 Tablet is taken orally.

Side Effects of Amlosafe Mt 50 Tablet 10

Fatigue
Nausea
Stomach pain
Indigestion
Headache
Dizziness
Double vision
Confusion

Managing the Side Effects:

Most of the side effects of Amlosafe MT 50 Tablet are temporary and are resolved once you discontinue the medicine. Here are some guidelines for managing the following side effects:

Nausea: Try taking Amlosafe MT 50 Tablet with food or milk.
Stomach pain: Consider taking this medicine after meals to lessen this effect.

Amlosafe MT 50 Tablet contains the following components:

Amlodipine (5 mg): Amlodipine belongs to a class of medicines called calcium channel blockers. It works by inhibiting the influx of calcium ions into the smooth muscles lining your blood vessels and heart. This causes the blood vessels to relax and widen, thereby reducing blood pressure. Additionally, it increases oxygen delivery to the heart muscle, which is particularly beneficial in managing angina.
Metoprolol Succinate (50 mg): Metoprolol succinate falls under beta-blockers, specifically targeting beta-1 adrenergic receptors found predominantly in your heart. Its action decreases cardiac output and suppresses the release of renin from the kidneys, thus lowering blood pressure further. Moreover, it reduces the workload on your heart, leading to a decreased demand for oxygen, which aids in preventing angina attacks.

Pregnancy

If you're pregnant, caution is advised while using Amlosafe MT 50 Tablet. Weigh the benefits against the risks and consult your doctor before using this medicine.

Breastfeeding

Amlosafe MT 50 Tablet is present in breast milk. If you are breastfeeding, it's best to avoid this medicine and seek your doctor's advice.

Alcohol

Drinking alcohol while taking Amlosafe MT 50 Tablet may increase side effects such as dizziness and fainting. Try to limit your alcohol intake while on this medication.

Liver

Careful monitoring is advised with Amlosafe MT 50 Tablet if you have mild to moderate liver problems. This medicine is not recommended if you have severe liver disease. Always discuss your health status with your doctor.

Kidney

The use of Amlosafe MT 50 Tablet in patients with severe kidney impairment should be done with caution. Consult your doctor before starting this medication if you have any kidney issues.

Using Machines & Driving

Amlosafe MT 50 Tablet may cause dizziness or tiredness. Be cautious when driving or operating machinery until you know how this medicine affects you.

Allergy

If you are allergic to amlodipine, metoprolol or any other ingredients of Amlosafe MT 50 Tablet, avoid using this medicine. Discuss any allergies you have with your doctor first.

Children

The safety and effectiveness of Amlosafe MT 50 Tablet haven't been established in children. Always check with your doctor before giving any medicine to a child.

Older Patients

Older patients should begin using Amlosafe MT 50 Tablet at a low dose under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of Amlosafe Mt 50 Tablet 10

Drug-Drug Interactions

Antibiotics such as clarithromycin, erythromycin, or rifampicin: Antibiotics can increase the effect of this tablet.
Calcium channel blockers such as diltiazem: These medications can decrease the effectiveness of the this tablet.
Antifungal medicines such as itraconazole or ketoconazole: These medications can increase the efficacy of this tablet.
Anti-epilepsy medicines such as carbamazepine and phenytoin: These medications can reduce the efficacy of this tablet.
Immunosuppressants such as ciclosporin or tacrolimus: These medications may affect the absorption of this tablet.
Antiarrhythmics such as quinidine and propafenone. The concomitant use may increase the effect of this tablet.
Selective serotonin reuptake inhibitor (SSRI) antidepressant such as fluoxetine and paroxetine. The concomitant use may increase the effect of this tablet.

Drug-Food Interactions

Amlosafe MT 50 Tablet has no known specific interactions with any foods.

Drug-Disease Interactions

Liver disease: Patients with severe liver problems need to be cautious as this medicine may not work as intended.
Heart conditions: Patients with conditions like bradycardia (slow heart rate), heart block, or heart failure should avoid this medicine as it could worsen their condition.
Diabetes: This medicine could interfere with your blood glucose control, making it important to monitor your sugar levels closely.
Peripheral arterial disease and Raynaud's phenomenon: This medicine might worsen these conditions. Regular monitoring is necessary.
Asthma or COPD: Patients with these respiratory conditions need to use this medicine with caution as it may cause bronchospasm (tightening of the muscles that line the airways).

Daily Dose

The daily dose of Amlosafe MT 50 Tablet should be taken as recommended by your doctor. The dosage may vary depending on factors such as how severe your condition is and how you respond to the medicine. Always stick to the prescribed dosage and avoid making any changes without consulting your doctor.

Over Dose

In case of an overdose, you might experience symptoms like extreme sleepiness or dizziness. If you suspect that you have taken more than the prescribed amount, it's important to inform your doctor.

Missed Dose

If you forget to take a dose of Amlosafe MT 50 Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your usual schedule. Never take a double dose to make up for a missed one without consulting your doctor.

Store Amlosafe MT 50 Tablet at room temperature.
Keep the medicine protected from light and moisture to maintain its effectiveness.
Always keep this medication out of the reach of children.
Use the medicine before its expiry date for optimum results.

Reduce your salt intake, as it can raise your blood pressure, counteracting the effect of Amlosafe MT 50 Tablet.
Engage in regular physical activities like brisk walking or cycling. This helps lower your blood pressure and keeps your heart healthy, assisting the work of Amlosafe MT 50 Tablet.

Fact Box

Drug Category	Calcium Channel Blocker, Beta-1 Blocker
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Angina

What is Amlosafe MT 50 Tablet used for?

Amlosafe MT 50 Tablet is typically used to manage high blood pressure and chest pain due to heart conditions.

Can I take Amlosafe MT 50 Tablet at any time of day?

Yes, but it's recommended to take it at the same time each day for the best outcome.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Don't double up.

Can I crush or chew the tablet?

No, you must swallow the extended-release tablet whole; crushing or chewing can interfere with its intended effect.

How long does it take for Amlosafe MT 50 Tablet to start working?

While full effects on blood pressure might take a few weeks, relief from chest pain should be noticeable within a few doses.

Can I stop taking Amlosafe MT 50 Tablet if I feel better?

No, do not stop taking this medicine without consulting your doctor first, as sudden discontinuation can exacerbate certain conditions.

Is Amlosafe MT 50 Tablet safe during pregnancy or while breastfeeding?

Both components of this medicine are present in breast milk and may have risks during pregnancy. Please consult your doctor before use.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

23 A, Shah Industrial Estate, Off Veera Desai Rd, Andheri West, Mumbai, Maharashtra 400053

Country of origin: INDIA

References

U.S. National Library of Medicine. (n.d.). DailyMed - AMLODIPINE BESYLATE tablet. Retrieved April 1, 2024, from https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=56d031db-67ed-217d-e054-00144ff88e88&type=display
U.S. National Library of Medicine. (n.d.). DailyMed - METOPROLOL SUCCINATE tablet, extended release. Retrieved April 1, 2024, from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=5988bc0d-68dc-47bc-819d-2709572042ce
U.S. Food and Drug Administration. (2007). Label: Amlodipine Besylate- Amlodipine besylate tablet. Retrieved April 1, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/022026lbl.pdf
U.S. Food and Drug Administration. (2018). Label: Metoprolol Succinate- Metoprolol succinate tablet, extended release. Retrieved April 1, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210428s000lblReplacement.pdf

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