Apigat 25 Mg Tablet 30

Apigat 2.5 Tablet 30

Natco Pharma Ltd

Bottle of 30 Units

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Composition

Apixaban (2.5 Mg)

Strength:

5 MG 2.5 MG

Apigat 2.5 Tablet is primarily used to lower the risk of stroke and systemic embolism in individuals with non-valvular atrial fibrillation (NVAF). This medicine is an anticoagulant, which is a group of medicines that deter blood clot formation.

Beyond its main use, this medicine also aids in preventing deep vein thrombosis (DVT) and pulmonary embolism (PE) in patients who have undergone hip or knee replacement surgeries. It's also deployed for treating and preventing recurrent DVT and PE.

Before starting this medicine, it's important to consult your doctor for the correct dosage and frequency. Inform your doctor about any pre-existing conditions or ongoing medications you are on, as this can affect how the medicine works for you. If any side effects occur while taking this medicine, consult your doctor immediately. Make sure to continue taking the medicine for the full duration prescribed by your doctor for optimal results.

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Apigat 2.5 Tablet is used for the following conditions:

Reducing the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation
Prevention of deep vein thrombosis in patients post hip or knee replacement surgery
Protection against pulmonary embolism for patients who have gone through hip or knee replacement surgery
Treatment and prevention of recurring deep vein thrombosis
Management and prevention of recurrent pulmonary embolism.

Directions for Use of Apigat 2.5 Tablet 30

Administer Apigat 2.5 Tablet as follows:

Swallow the whole tablet with a glass of water.
Do not break, chew, or crush the tablet.
Follow your doctor's instructions on when to take the medicine.
Never self-adjust the dosage without consulting your doctor first.

Apigat 2.5 Tablet is taken orally.

Apigat 2.5 Tablet may have the following side effects:

Bleeding
Anaemia
Nausea
Bruising

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Apigat 2.5 Tablet. However, if you experience any serious side effects or worsening of any symptoms, please consult your doctor. Here are some tips to manage common side effects:

Bleeding: If minor bleeding like nosebleeds occur, try pinching your nostrils together and leaning forward slightly to reduce the bleeding.
Nausea: Try taking Apigat 2.5 Tablet with food or milk to lessen this effect.

Apigat 2.5 Tablet contains apixaban (2.5 mg), which affects your body as follows:

Selective Factor Xa Inhibition: Apixaban works by selectively inhibiting Factor Xa in your blood. Factor Xa plays a crucial role in the blood clotting process.
Thrombin Generation Reduction: By inhibiting Factor Xa, apixaban effectively diminishes thrombin generation.
Thrombus Development Decrease: Lowering thrombin production leads to a drop in thrombus development, which are clumps of blood cells that cause blood clots.

Through these actions, Apigat 2.5 Tablet helps prevent the formation of harmful blood clots in your arteries and veins, reducing the risk of associated conditions such as stroke and embolism.

Pregnancy

Apigat 2.5 Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, ensure to consult your doctor before starting this medicine.

Breastfeeding

Apigat 2.5 Tablet is contraindicated for breastfeeding women. It is crucial to consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while consuming alcohol during the course of Apigat 2.5 Tablet. Alcohol may intensify the risk of bleeding. It's recommended to consult your doctor.

Liver

Caution is advised while taking Apigat 2.5 Tablet in case of liver impairment. The medicine is not recommended for severe liver diseases. If you have liver problems, consult your doctor before starting this medication.

Kidney

If you have a history of kidney problems, caution is advised before using Apigat 2.5 Tablet. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

There isn't any specific information about the effect of Apigat 2.5 Tablet on driving or operating machinery. However, if you feel dizzy or have other side effects that could affect your concentration, avoid these activities and consult your doctor.

Allergy

If you have known allergies to apixaban or any other ingredients present in Apigat 2.5 Tablet, do not take this medicine without consulting with your doctor first.

Children

Apigat 2.5 Tablet isn't recommended for children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Apigat 2.5 Tablet under medical supervision, as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age, as they might have liver and kidney issues, and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Apigat 2.5 Tablet interacts with the following medicines:

Anticoagulants: Medicines like warfarin may interact with Apigat 2.5 Tablet, potentially increasing the risk of bleeding.
Antiplatelet agents: When taken with Apigat 2.5 Tablet, antiplatelet agents like aspirin and clopidogrel can amplify the anticoagulant effect, raising the chance of bleeding.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): NSAIDs such as ibuprofen and naproxen, when paired with Apigat 2.5 Tablet, can boost the likelihood of bleeding.
Selective Serotonin Reuptake Inhibitors (SSRIs): SSRI medications like fluoxetine or sertraline may increase the risk of bleeding when used alongside Apigat 2.5 Tablet.

Drug-Food Interactions

There are no specific known interactions between Apigat 2.5 Tablet and any particular foods or beverages.

Drug-Disease Interactions

Apigat 2.5 Tablet interacts with the following diseases:

Active Pathological Bleeding: An active bleeding condition can be worsened by taking Apigat 2.5 Tablet because it thins the blood.
Severe Hepatic Impairment: People with severe liver disease should be cautious as Apigat 2.5 Tablet could exacerbate their condition.

Daily Dose

As with any medication, the daily dose of Apigat 2.5 Tablet should be as prescribed by your doctor. This can vary based on individual factors such as the severity of your condition and response to treatment. Always adhere to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more Apigat 2.5 Tablets than prescribed, you might experience symptoms like nausea or excessive bruising. It's important not to panic; however, consult your doctor about the situation.

Missed Dose

In case you forget to take your Apigat 2.5 Tablet at the scheduled time, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and follow your regular schedule. Never double up on doses without consulting your doctor.

Store Apigat 2.5 Tablet at a stable temperature below 30°C.
Keep the medicine in its original packaging to protect it from light and moisture.
Always keep this medication out of reach of children.
Check the expiry date before use and never take it if it's past this date.

If you're taking Apigat 2.5 Tablet for non-valvular atrial fibrillation or deep vein thrombosis, try to maintain a balanced diet low in saturated fats to support overall heart health.
As this medication reduces clot formation, avoid activities with a high risk of injury or bleeding, like contact sports, to prevent unnecessary blood loss.

Fact Box

Drug Category	Direct Oral Factor Xa Inhibitor
Therapeutic Category	Anticoagulant
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Non-valvular atrial fibrillation, Deep vein thrombosis, Pulmonary embolism

What is Apigat 2.5 Tablet used for?

Apigat 2.5 Tablet is used to reduce the risk of blood clots, stroke, and embolism in certain conditions, including non-valvular atrial fibrillation and after hip or knee surgery.

How does Apigat 2.5 Tablet work?

Apigat 2.5 Tablet contains apixaban which inhibits a blood clotting factor called Factor Xa, thereby reducing the formation of blood clots in your body.

Can Apigat 2.5 Tablet be taken with food?

Yes, you can take Apigat 2.5 Tablet with or without food. Follow your doctor's instructions on how to take this medicine.

What should I do if I miss a dose of Apigat 2.5 Tablet?

If you miss a dose, take it as soon as you remember. However, if it's near to your next dose time, skip the missed one and follow your regular schedule.

Should I stop taking Apigat 2.5 Tablet without consulting my doctor?

No, abruptly stopping Apigat 2.5 Tablet can increase the risk of blood clots or stroke. Always consult your doctor before making any changes.

What should I do if I experience signs of bleeding while taking Apigat 2.5 Tablet?

If you observe signs of excessive bleeding like prolonged nosebleeds or red stools, consult your doctor immediately.

Can I take Apigat 2.5 Tablet if I have kidney problems?

Your doctor may adjust the dosage of Apigat 2.5 Tablet if you have kidney problems but always consult them before starting any medication.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Natco House Road No.2, Banjara Hills Hyderabad-500 034, India

Country of origin: INDIA

References

U.S. National Library of Medicine. (2021, March 15). Apixaban: MedlinePlus drug information. MedlinePlus. https://medlineplus.gov/druginfo/meds/a613032.html. Accessed on 1 April 2024.
Aspirinand clopidogrel-associated bleeding complications: Data mining of the public version of the FDA adverse event reporting system, AERS. (n.d.). PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410363/
Surfing the blood coagulation Cascade: Insight into the vital factor Xa. (n.d.). PubMed. https://pubmed.ncbi.nlm.nih.gov/29376487/

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