Aricep M 55 Mg Tablet 10

Aricep M Tablet 10

Eisai Pharmaceuticals India Ltd

Strip of 10 Units

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Composition

Donepezil (5 Mg) + Memantine (5 Mg)

Aricep-M Tablet is primarily used to manage moderate to severe dementia connected with Alzheimer's disease. This is a combination medicine that falls within the category of medications known as N-methyl-D-aspartate (NMDA) receptor antagonists and acetylcholinesterase inhibitors.

Aside from this main usage, this medicine can also help enhance memory, awareness, and the ability to perform daily functions in individuals suffering from Alzheimer's dementia. This is because it targets cholinergic and glutamatergic pathways, which play key roles in memory and learning.

Before starting this medicine, it's important to consult your doctor, who can guide you on the correct dosage and frequency. You should also inform your doctor about any pre-existing conditions or ongoing medications. If you experience any side effects while taking this medicine, inform your doctor immediately. To achieve the best results, it's crucial to continue taking the medicine for the full duration prescribed by your doctor.

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Aricep-M Tablet is used for the following:

Managing moderate to severe dementia linked to Alzheimer's disease
Boosting memory and awareness in Alzheimer's patients
Enhancing the ability to do daily activities in individuals with Alzheimer's dementia
Slowing down the progression of cognitive decline in Alzheimer's disease

Directions for Use of Aricep M Tablet 10

Here's how to take Aricep-M Tablet:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Always follow your doctor's instructions about the dose and schedule.
Remember not to abruptly stop taking this medicine without consulting your doctor.

Aricep-M Tablet is taken orally.

Aricep-M Tablet may lead to certain side effects:

Nausea
Vomiting
Diarrhoea
Anorexia: This is a loss of appetite that could potentially lead to weight loss.
Abdominal pain
Dizziness
Insomnia
Fatigue
Muscle cramps

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Aricep-M Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips for managing common side effects:

Nausea and Vomiting: Try taking Aricep-M Tablet with food.
Diarrhoea: Stay hydrated by drinking plenty of fluids.

Aricep-M Tablet has two active ingredients:

Donepezil (5 mg): This ingredient belongs to the class of medications known as acetylcholinesterase inhibitors. Its role is to boost the levels of acetylcholine, a neurotransmitter involved in memory and learning, by slowing its breakdown in the brain. It helps in enhancing cholinergic function which is key for memory and learning.
Memantine (5 mg): This is an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. It works by controlling the activity of glutamate, another neurotransmitter involved in learning and memory. By blocking the NMDA receptors, memantine shields the brain from the harmful effects associated with excess glutamate and improves the signal-to-noise ratio in the cortex and hippocampus.

Pregnancy

Caution is advised when taking Aricep-M Tablet during pregnancy. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it is recommended that you discuss this with your doctor before starting Aricep-M Tablet.

Alcohol

The effects of alcohol on the action of Aricep-M Tablet are not well understood. It's best to consult your doctor before consuming alcohol while on this medication.

Liver

Aricep-M Tablet should be used under medical supervision if you have liver problems. Your doctor will determine if this medicine is suitable based on your health status.

Kidney

If you have kidney problems, caution is advised when using Aricep-M Tablet. Always consult your doctor for guidance.

Using Machines & Driving

Aricep-M Tablet may cause dizziness and somnolence, affecting your ability to drive or operate machinery. Exercise caution and consult your doctor for advice.

Allergy

If you have a known allergy to donepezil or memantine, the active ingredients in Aricep-M Tablet, avoid using this medication. Consult your doctor about other treatment options.

Children

It's advisable to consult your doctor before giving Aricep-M Tablet to children under 18.

Older Patients

Older patients may be more susceptible to the side effects of Aricep-M Tablet. Therefore, they should take this medicine under medical supervision. If you are above 70 years old, please discuss any liver or kidney-related concerns with your doctor before starting this medication.

Drug-Drug Interactions

Aricep-M Tablet interacts with the following medicines:

Anticholinergic Medications: Aricep-M Tablet can increase side effects such as dry mouth, blurred vision, and urinary retention when taken with anticholinergic medicines like atropine, benztropine, or trihexyphenidyl.
Cholinergic Agonists: Taking Aricep-M Tablet and cholinergic agonists like bethanechol or pilocarpine could lead to excessive nervous system stimulation.
Heart Rate Lowering Medications: Caution is necessary if you're taking beta-blockers or digoxin, as Aricep-M Tablet can further slow down your heart rate.
NMDA Antagonists: Amantadine, ketamine, and dextromethorphan could interact with Aricep-M Tablet, leading to an increased risk of psychotic symptoms and seizures.

Drug-Food Interactions

Certain food items may impact how Aricep-M Tablet works in your body.

Drug-Disease Interactions

Aricep-M Tablet interacts with the following diseases:

Cardiovascular Conditions: If you have heart-related issues, use Aricep-M Tablet cautiously as it can cause slow heartbeat and fainting spells.
Respiratory Conditions: For people with asthma or chronic obstructive pulmonary disease (COPD), this medicine may worsen symptoms.
Peptic Ulcers: If you're at risk for peptic ulcers, Aricep-M Tablet could exacerbate your condition.
Seizure Disorders: Aricep-M Tablet may cause seizures, particularly in patients with a history of such disorders.

Daily Dose

The daily dose of Aricep-M Tablet should be taken as advised by your doctor. This might change depending on individual factors such as how severe the condition is and how you respond to the medicine. Always stick to the prescribed dosage and avoid taking more without speaking to your doctor first.

Over Dose

An overdose of Aricep-M Tablet could cause symptoms like increased sweating, salivation, muscle weakness, and restlessness. If you suspect that you have taken too much of this medicine, it's crucial to inform your doctor straight away.

Missed Dose

If you forget to take your Aricep-M Tablet, take it as soon as you remember. But if it's almost time for your next dose, leave out the one you missed and continue with your regular schedule. Don't take extra tablets to make up for a missed dose without consulting your doctor.

Store Aricep-M Tablet in a dry place, away from light and moisture.
The ideal temperature for storage is between 15-30°C.
Do not expose the medicine to extreme heat or cold.
Keep Aricep-M Tablet out of reach of children.
Always use the medicine before its expiry date.

Engage in regular mental exercises like puzzles, reading, or memory games. This could potentially help manage Alzheimer's dementia by keeping your mind active.
Maintaining a balanced diet rich in fruits, vegetables, lean protein, and whole grains may support overall brain health and may aid in managing symptoms of Alzheimer's dementia.

Fact Box

Drug Category	Acetylcholinesterase Inhibitor, NMDA Receptor Antagonist
Therapeutic Category	Alzheimer's Disease Management
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Moderate to Severe Alzheimer's Dementia

What is Aricep-M Tablet used for?

Aricep-M Tablet is a medicine used to manage moderate to severe dementia linked to Alzheimer's disease, improving memory, awareness and daily functionality.

How does Aricep-M Tablet work?

The tablet contains donepezil, which increases a brain chemical (acetylcholine) involved in memory and learning, while memantine regulates another (glutamate), improving brain function.

When should I take Aricep-M Tablet?

Aricep-M Tablet is usually taken once daily, preferably in the evening. However, always follow your doctor's specific instructions regarding when to take your medicine.

Can I take Aricep-M Tablet with food?

Yes, you can take Aricep-M Tablet with or without food. It is important to swallow the tablet whole with water.

What should I be cautious of while using Aricep-M Tablet?

Patients with cardiovascular conditions, asthma, risk for peptic ulcers, seizure disorders or bladder outflow obstruction should use Aricep-M Tablet cautiously after consulting a doctor.

What are some side effects of Aricep-M Tablet?

Common side effects include nausea, vomiting, diarrhoea, abdominal pain and dizziness. Less common but serious side effects may include seizures and bradycardia. Consult your doctor if these persist.

Can Aricep-M Tablet interact with other medicines?

Yes, it can interact with medicines that have anticholinergic properties or slow heart rate. Always discuss all medications you're taking with your doctor before starting Aricep-M Tablet.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

6th Floor, A Wing, Marwah Centre, Krishanlal Marwah Marg, Andheri East, Mumbai, Maharashtra 400072

Country of origin: INDIA

References

MedlinePlus. (n.d.). Donepezil: MedlinePlus Drug Information. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a697032.html
MedlinePlus. (n.d.). Memantine: MedlinePlus Drug Information. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a604006.html
U.S. Food and Drug Administration. (2006). NAMENDA (memantine hydrochloride) tablets. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/020690s026,021720s003lbl.pdf
U.S. Food and Drug Administration. (2005). ARICEPT (donepezil hydrochloride) tablets. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021627lbl.pdf
Donepezil. (n.d.). Retrieved 15 October 2024, from
https://go.drugbank.com/drugs/DB00843
Memantine. (n.d.). Retrieved 15 October 2024, from https://go.drugbank.com/drugs/DB01043

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