Axegliptin M 20500mg Tablet Er 10

Axegliptin M 500 Tablet 10

Ajanta Pharma Ltd

Strip of 10 Units

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MRP ~~₹149~~

₹74.35

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Composition

Metformin (500 Mg) + Teneligliptin (20 Mg)

Axegliptin M 500 Tablet 10is primarily used for managing type 2 diabetes mellitus in adults. This combination medicine belongs to a class of medications known as antihyperglycemics.

It aids in improving blood sugar control when metformin alone fails to do so, thus reducing the risk of severe complications associated with diabetes, such as kidney damage and vision loss. It can also prevent other problems like nerve disorders.

You should take this medicine as directed by your doctor. Before starting, it is important to tell your doctor about any existing health conditions or ongoing medications. If you experience any side effects while taking this medication, please inform your doctor straight away. For optimal results, you should continue taking the medicine for the duration prescribed by your doctor.

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Axegliptin M 500 Tablet 10is used for the following:

Controlling blood sugar levels in adults with type 2 diabetes
Enhancing the effect of diet and exercise in managing type 2 diabetes
Reducing the risk of severe complications associated with high blood sugar levels, such as kidney damage and vision loss
Improving blood sugar control when metformin alone cannot manage it adequately

Directions for Use of Axegliptin M 500 Tablet 10

Follow these instructions while taking Denedel M Tablet:

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
Do not take more than the recommended dose without consulting your doctor.
It's important not to stop taking this medicine without speaking to your doctor first.

Axegliptin M 500 Tablet 10is taken orally.

Side Effects of Axegliptin M 500 Tablet 10

Axegliptin M 500 Tablet 10might have the following common side effects:

Diarrhoea
Nausea
Vomiting
Abdominal pain or discomfort
Flatulence: This is when you get excess gas in your digestive system, and you might feel bloated or pass wind more than usual.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Denedel M Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Abdominal pain or discomfort: Take this medicine with your evening meal to lessen this effect.
Flatulence: Try taking Axegliptin M 500 Tablet 10with food to reduce gas production.

Axegliptin M 500 Tablet 10contains two active ingredients:

Metformin Hydrochloride (500 mg): As a biguanide antihyperglycemic agent, metformin reduces glucose in the liver, decreases glucose absorption in the intestines, and enhances insulin sensitivity. This combination helps to lower blood sugar levels throughout the day.
Teneligliptin Hydrobromide Hydrate (20 mg): Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It operates by slowing down the breakdown process of incretin hormones like GLP-1 and GIP. This action boosts their effects, leading to increased insulin production when blood sugar is high and decreased glucose production by the liver.

Together, these ingredients provide comprehensive control over blood sugar levels in adults with type 2 diabetes.

Pregnancy

Caution is advised while taking Axegliptin M 500 Tablet 10if you are pregnant. It's best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, please consult your doctor before starting Denedel M Tablet.

Alcohol

It's important to limit alcohol consumption while taking Denedel M Tablet, as it might enhance the risk of lactic acidosis with metformin.

Liver

If you have any liver health issues, discussing them with your doctor before starting Axegliptin M 500 Tablet 10is advisable.

Kidney

Axegliptin M 500 Tablet 10should be used cautiously if you have any kidney health issues. Your doctor will guide you based on your health status.

Using Machines & Driving

Axegliptin M 500 Tablet 10doesn't usually affect your ability to operate machinery or drive. However, avoid driving or operating heavy machines if you experience side effects like dizziness or weakness.

Allergy

If you have ever had an allergic reaction to metformin or teneligliptin, do not take Denedel M Tablet.

Children

Axegliptin M 500 Tablet 10is intended for adult use. It should not be given to children under 18 years of age.

Older Patients

Older patients should take Axegliptin M 500 Tablet 10under medical supervision as they may be more susceptible to its effects. Your doctor will guide you based on your health status.

Interactions of Axegliptin M 500 Tablet 10

Drug-Drug Interactions

Axegliptin M 500 Tablet 10interacts with the following medicines:

Cationic Medicines: Medicines like amiloride, digoxin, and morphine can slow down the elimination of metformin from your body. This could lead to a buildup of metformin, increasing the risk of side effects.
Diuretics: Certain medications like furosemide could decrease kidney function and increase the risk of lactic acidosis when you're taking metformin.
Glucose-Altering Medicines: Certain medications, such as isoniazid, can interfere with blood sugar levels, influencing the effectiveness of Denedel M Tablet.

Drug-Food Interactions

There are no known specific food interactions with Denedel M Tablet.

Drug-Disease Interactions

Axegliptin M 500 Tablet 10interacts with certain diseases:

Kidney Disease: If you have kidney disease, your body may not be able to clear metformin properly. This can increase medicine levels in your body and cause side effects.
Liver Disease: Metformin is broken down by the liver. If you have liver disease, it may affect how well your body breaks down and removes this medicine.
Heart Disease: If you have a condition where your heart can't pump blood as well as it should (heart failure), taking Axegliptin M 500 Tablet 10might increase your risk of lactic acidosis.

Daily Dose

The daily dose of Axegliptin M 500 Tablet 10should be taken as prescribed by your doctor. The dosage can vary based on individual factors, such as the severity of your condition and how you respond to the medication. It's critical to adhere to the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

Overdosing on Axegliptin M 500 Tablet 10might lead to common side effects like nausea, abdominal pain, or diarrhoea. If you suspect an overdose, reach out to your doctor for guidance.

Missed Dose

If you've missed a dose of Denedel M Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store Axegliptin M 500 Tablet 10at room temperature.
Keep the medicine in a cool, dry place, away from direct sunlight.
Ensure the storage area is moisture-free to maintain the tablet's effectiveness.
Always keep this medicine out of reach of children.

Since Axegliptin M 500 Tablet 10is used to manage type 2 diabetes, incorporating a balanced diet low in sugar and high in fibre can help control blood glucose levels.
Regular physical exercise, such as brisk walking or cycling, will also help maintain healthy blood sugar levels and improve overall health.

Fact Box

Drug Category	Biguanide Antihyperglycemic, DPP-4 Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 diabetes mellitus

Can I stop taking Axegliptin M 500 Tablet 10if I feel better?

No, you shouldn't stop taking Axegliptin M 500 Tablet 10without consulting your doctor. This medicine helps manage your blood sugar levels continuously.

What happens if I miss a dose of Denedel M Tablet?

If you miss a dose, take it as soon as you remember. However, skip the missed dose if it's nearly time for the next one. Don't double up your dosage to compensate for the missed one.

How long does it take for Axegliptin M 500 Tablet 10to start working?

The effect on blood sugar control can generally be noticed within two weeks, but full benefits may take 2 to 3 months to become evident. In general, it depends on your health status and the severity of your condition.

Can I take a Axegliptin M 500 Tablet 10during pregnancy or breastfeeding?

Axegliptin M 500 Tablet 10is not recommended during pregnancy or breastfeeding. Always consult your doctor for advice on this matter.

What should I avoid while taking the Denedel M Tablet?

It's advisable to avoid excessive alcohol consumption as it can increase the risk of lactic acidosis, especially when combined with metformin.

Can Axegliptin M 500 Tablet 10cause side effects?

Yes, common side effects include diarrhoea, nausea, and vomiting among others. If any of these persist or worsen, consult your doctor immediately.

Are there specific foods I should avoid while taking Denedel M Tablet?

No specific food restrictions are noted for this medication, but maintaining a balanced diet is always beneficial in managing type 2 diabetes.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

54, Sir Mathuradas Vasanji Rd, Hanuman Nagar, Andheri East, Mumbai, Maharashtra 400053

Country of origin: INDIA

References

Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.-c). DrugBank. https://go.drugbank.com/drugs/DB00331
Teneligliptin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB11950
U.S. National Library of Medicine. (2021). METFORMIN HYDROCHLORIDE tablet, film coated [Candela Healthcare]. DailyMed. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2a. Accessed 1 April 2024.
Yamada, Y., & Kato, T. (2021). Teneligliptin: A DPP-4 inhibitor for the treatment of type 2 diabetes. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 14, 2041–2058. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805719/. Accessed 1 April 2024.
U.S. Food and Drug Administration. (2006). Metformin hydrochloride tablet, film coated [label]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf. Accessed 1 April 2024.

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