Bioval 200 Tablet 10

Biochem Pharmaceutical Inds

Strip of 10 Units

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MRP ~~₹40.09~~

₹32.07

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Composition

Sodium Valproate / Valproic Acid (200 Mg)

Bioval 200 Tablet 10 is primarily used for managing epilepsy, a condition characterised by recurrent seizures. This medicine falls under the category of anti-epileptic medications.

In addition to managing epilepsy, this medicine also helps in the management of bipolar disorder by restoring balance in nerve activity within the brain, thus preventing extreme mood swings. It is also utilised in preventing migraines.

It's crucial to take this medicine as directed by your doctor, who will decide the right dosage based on your specific condition and response to treatment. You should promptly inform your doctor about any pre-existing health conditions or ongoing medications before you start taking this medicine. Report any side effects to your doctor immediately, and continue taking the medicine for the duration prescribed by your doctor to achieve optimal results.

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Bioval 200 Tablet 10 is used for:

Managing epilepsy, controlling seizures or fits
Maintaining the balance of nerve activity in bipolar disorder
Preventing extreme mood swings in bipolar disorder
Reducing episodes of mania and depression in bipolar disorder
Preventing migraines

Directions for Use of Bioval 200 Tablet 10

Swallow the tablet whole with water.
Do not crush or chew the tablet.
Always take the medicine at evenly spaced intervals throughout the day.
Never exceed the prescribed dose without consulting your doctor.
Do not stop taking this medicine suddenly; discontinuation should be under a doctor's supervision.

Bioval 200 Tablet 10 is taken orally.

Bioval 200 Tablet 10 may have the following common side effects:

Nausea
Vomiting
Diarrhoea
Abdominal pain
Dizziness
Drowsiness
Unsteadiness while walking

Managing the Side Effects:

Most side effects are temporary and generally harmless, and resolve upon discontinuing the use of Bioval 200 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea or vomiting: Try taking Bioval 200 Tablet 10 with food to reduce these effects.
Unsteadiness while walking: If this medicine makes you unsteady during the day, consider taking it at night instead.

Bioval 200 Tablet 10 contains sodium valproate (200 mg), which works in your body by stabilizing brain electrical activity to control seizures.

Anticonvulsant action: Sodium valproate works by controlling excessive and abnormal nerve activity in your brain that leads to seizures.
Mood stabilisation: In cases of bipolar disorder, sodium valproate helps restore the normal balance of nerve activity within the brain, thus avoiding extreme mood fluctuations.

Pregnancy

Bioval 200 Tablet 10 may cause harm to the foetus and result in birth defects if taken during pregnancy. If you are pregnant or planning to conceive, consult your doctor before starting this medicine.

Breastfeeding

Use caution if you are breastfeeding while taking Bioval 200 Tablet 10. Consult your doctor to understand the potential risks and benefits before taking this medicine.

Alcohol

It is best to avoid alcohol while taking Bioval 200 Tablet 10 as it might interfere with the medicine's effectiveness. Consult your doctor for more information.

Liver

If you have liver-related issues, be careful while taking Bioval 200 Tablet 10. This medicine is not recommended if you have severe liver disease or significant liver dysfunction.

Kidney

Caution is advised if you have a history of kidney problems. It is advisable to consult your doctor before taking this medicine.

Using Machines & Driving

Since Bioval 200 Tablet 10 can cause dizziness, drowsiness, and unsteadiness while walking, it's best to avoid operating heavy machinery or driving while on this medication.

Allergy

Bioval 200 Tablet 10 is contraindicated if there's known hypersensitivity to sodium valproate, valproic acid, or any other ingredients in the tablet. Ensure your doctor is aware of any allergies you may have.

Children

Young children below 2 years should take Bioval 200 Tablet 10 under medical supervision due to a higher risk of liver damage. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Bioval 200 Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are over 70 years old. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Bioval 200 Tablet 10 interacts with the following medicines:

Anti-epileptic medicines: Medicines such as phenytoin, carbamazepine, and lamotrigine may interact with Bioval 200 Tablet 10, potentially altering the effects of either medicine.
Anticoagulants: Medicines like warfarin may interact with Bioval 200 Tablet 10, which could increase the risk of excessive bleeding.
Nonsteroidal anti-inflammatory drugs (NSAIDs): Certain NSAIDs like aspirin, when taken along with Bioval 200 Tablet 10, can increase the levels of sodium valproate in your blood.
Depressant medicines: Medicines like diazepam and alprazolam may have their sedative effects amplified when taken with Bioval 200 Tablet 10.
Antibiotics: Certain antibiotics, such as erythromycin, can interact with Bioval 200 Tablet 10, potentially leading to altered medicine effects or increased risk of side effects.
Antidepressants: Taking antidepressants like fluoxetine or sertraline along with Bioval 200 Tablet 10 may impact the effectiveness of these medicines.

Drug-Food Interactions

None

Drug-Disease Interactions

Bioval 200 Tablet 10 interacts with the following diseases:

Liver disease: If you have liver disease or significant liver dysfunction, Bioval 200 Tablet 10 could exacerbate your condition.
Urea cycle disorders: Individuals with known urea cycle disorders should exercise caution, as Bioval 200 Tablet 10 can interfere with the body's ability to remove ammonia from the bloodstream.
Porphyria: This medicine might worsen this rare genetic metabolic disorder by interfering with heme synthesis, leading to increased production of porphyrins.
Mitochondrial disorders: Bioval 200 Tablet 10 could exacerbate conditions caused by mutations in the mitochondrial DNA polymerase γ (POLG) gene.

Daily Dose

The recommended dose of Bioval 200 Tablet 10 is as advised by your doctor. The dosage might vary based on your individual health conditions and how your body responds to the medicine. For detailed instructions, please refer to the package insert.

Over Dose

If you consume more than the recommended dose of Bioval 200 Tablet 10, you may experience symptoms like profound drowsiness or feelings of deep sleep. In such scenarios, it is crucial to inform your doctor.

Missed Dose

In case you forget to take your dose of Bioval 200 Tablet 10, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not increase the dosage without consulting your doctor.

Store Bioval 200 Tablet 10 at normal room temperature, ideally below 30°C.
Keep it away from direct light and moisture.
Ensure the medicine is kept out of reach and sight of children.
Always check the expiry date on the package before use.

If you're taking Bioval 200 Tablet 10 for epilepsy or bipolar disorder, try to maintain a regular sleep schedule. Sleep disruptions may trigger seizures or mood changes.
For migraine prevention, attempt to identify and avoid potential triggers such as certain foods, bright lights, or loud sounds. A daily headache diary can help identify these triggers.

Fact Box

Drug Category	Anticonvulsant
Therapeutic Category	Anti-epileptic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Epilepsy, Bipolar disorder, Migraine prevention

What is Bioval 200 Tablet 10 used for?

Bioval 200 Tablet 10 is used to manage epilepsy and bipolar disorder and to prevent migraines.

How does Bioval 200 Tablet 10 work in epilepsy?

It controls excessive and abnormal nerve activity in the brain that causes seizures, reducing confusion and jerking movements.

Can Bioval 200 Tablet 10 help with bipolar disorder?

Yes, it restores the normal balance of nerve activity in the brain, reducing manic and depressive episodes in bipolar disorder.

Can I take Bioval 200 Tablet 10 for migraine prevention?

Yes, it's thought to regulate abnormal nerve activity in the brain that may trigger migraines, potentially reducing their frequency. Consult your doctor to know about its effect on migraine prevention.

Are there any precautions before taking Bioval 200 Tablet 10?

If you have liver disease, urea cycle disorders, porphyria, or mitochondrial disorders, you should avoid this medicine. Always consult your doctor first.

What are the side effects of Bioval 200 Tablet 10?

Common side effects include nausea, dizziness, unsteadiness while walking and tremors. Rarely, it can cause serious adverse effects. Consult your doctor in case symptoms persist or worsen.

What happens if I overdose on Bioval 200 Tablet 10?

Overdose symptoms, such as deep sleep, require immediate medical attention. Always adhere to the prescribed dosage for safe use.

Last Updated On 02 Jan. 2025 | 5:41AM (IST)

Certified Content

Written by

Dr Vatsalya D Ghanekar

Medical Content Writer | 5 years

MD Ayurveda

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 7 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Aidun Building,John Crasto Lane,Near- Metro Theatre, Mumbai, Maharashtra 400002

Country of origin: INDIA

References

Sodium Valproate 500mg Gastro-Resistant Tablets - Summary of Product Characteristics (SmPC) https://www.medicines.org.uk/emc/product/1500/smpc#gref
Rahman, M., Awosika, A. O., & Nguyen, H. (2024, March 19). Valproic acid. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK559112/
Muthaffar, O. Y., Almahmudi, S. M., Alrabghi, M. O., Bin Mahfouz, M. M., & Alfawaz, N. S. (2021). Valproic acid for children below 2 years of age with epilepsy. Neurosciences (Riyadh, Saudi Arabia), 26(4), 357–365. https://doi.org/10.17712/nsj.2021.4.20210075
Sodium valproate: medicine to treat epilepsy and bipolar disorder. https://www.nhs.uk/medicines/sodium-valproate/
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 16760703, Valproate Sodium. Retrieved August 12, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Valproate-Sodium.

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