Bisonext Am 5 Tablet 15

Lupin Ltd

Strip of 15 Units

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MRP ~~₹171.8~~

₹141.06

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Composition

Amlodipine (5 Mg) + Bisoprolol (5 Mg)

Bisonext AM 5 Tablet is primarily used to manage hypertension, also known as high blood pressure. This medication is a combination medicine that falls under the category of antihypertensives.

Apart from its main use, this tablet also plays a crucial role in reducing the risk of severe cardiovascular events, such as strokes and heart attacks. By effectively controlling high blood pressure, it can potentially prevent these adverse health outcomes.

Before taking this medicine, you should consult your doctor for the appropriate dosage and frequency. It's important to inform your doctor about any pre-existing conditions or ongoing medications you may have. If you notice any side effects while on this medication, report them to your doctor immediately. For optimal results, continue taking the medicine for the duration your doctor prescribes.

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Lowering high blood pressure or hypertension
Reducing the risk of fatal and non-fatal cardiovascular events, primarily strokes and heart attacks

Directions for Use of Bisonext Am 5 Tablet 15

Swallow the tablet whole with a glass of water.
Don't crush or chew the tablet.
Make sure to take it at the same time each day, with or without food.
Continue taking it for as long as your doctor advises, and don't stop suddenly without consulting your doctor

Bisonext AM 5 Tablet is taken orally.

Headache
Dizziness
Fatigue: This refers to a state of feeling very tired or weak.
Oedema: This is swelling in ankles, feet, hands due to fluid accumulation.
Slow heartbeat
Nausea
Diarrhoea
Flushing: This means becoming red and warm suddenly.
Stomach pain
Insomnia: It is a sleep disorder where you may have trouble falling asleep or staying asleep.

Managing the Side Effects:

Diarrhoea: Try taking Bisonext AM 5 Tablet with food to lessen this effect.
Stomach pain: If you have stomach pain after taking this medicine, consider taking it after meals.

Bisonext AM 5 Tablet consists of the following two components:

Amlodipine (5 mg): As a calcium channel blocker, Amlodipine works by relaxing your blood vessels, making it easier for your heart to pump blood. This action reduces the resistance in your peripheral vascular system and lowers your blood pressure.
Bisoprolol (5 mg): This is a beta-1 selective adrenoceptor blocking agent. Its job is to block certain natural chemicals like epinephrine from affecting your heart and blood vessels. This results in a reduced heart rate and blood pressure, lessening the strain on your heart.

Pregnancy

Bisonext AM 5 Tablet may cause harm to the unborn baby. It's recommended to consult your doctor before taking this medicine during pregnancy.

Breastfeeding

This medicine is not recommended for breastfeeding women as it is present in human milk. If you are currently breastfeeding, consult your doctor to understand potential risks and benefits.

Alcohol

Combining Bisonext AM 5 Tablet and alcohol may intensify some side effects like dizziness. For this reason, it is best to avoid alcohol while on this medication.

Liver

If you have mild to moderate liver impairment, take caution when using Bisonext AM 5 Tablet. It's not recommended for severe liver diseases. Discuss any liver health issues with your doctor before using this medicine as it might affect liver function.

Kidney

Caution is advised if you have a history of kidney problems. It's a good idea to consult your doctor before taking Bisonext AM 5 Tablet.

Using Machines & Driving

Bisonext AM 5 Tablet may cause side effects such as dizziness or fatigue that could affect your ability to drive or operate machinery. It's best to avoid such activities until you know how the medicine affects you.

Allergy

Avoid using Bisonext AM 5 Tablet if you have known allergies to Amlodipine or Bisoprolol or any other ingredients in the medicine. If you notice any allergic reactions after taking it, seek immediate medical attention.

Children

Caution is advised when giving it to individuals under the age of 18 years.

Older Patients

Elderly patients should take Bisonext AM 5 Tablet under medical supervision due to their increased susceptibility to side effects and potential liver or kidney issues. Your doctor will guide you based on your health status if you are above 70 years of age.

Drug-Drug Interactions

Antihypertensives: Other blood pressure-lowering medicines, like atenolol and ramipril, may cause an additive effect when taken with Bisonext AM 5 Tablet, leading to excessively low blood pressure.
Digitalis Glycosides: Medicines like digoxin can increase the risk of an abnormally slow heart rate (bradycardia) when taken with this tablet.
CYP3A4 Inhibitors: Medicines such as itraconazole and ritonavir might reduce how quickly Bisonext AM 5 Tablet is removed from your body, potentially increasing its effects or side effects.
Immunosuppressants and Statins: Cyclosporine, tacrolimus, and simvastatin can lead to increased levels and potential toxicity when taken with this tablet.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): NSAIDs like ibuprofen could decrease the blood pressure-lowering effect of Bisonext AM 5 Tablet.

Drug-Food Interactions

There are no specific food items known to interact with Bisonext AM 5 Tablet. However, it's generally best to take medicine at the same time each day for maximum effectiveness.

Drug-Disease Interactions

Cardiogenic Shock and Severe Bradycardia: This tablet should not be used in patients with these heart conditions as it could exacerbate symptoms.
Severe Hypotension: Patients with extremely low blood pressure should avoid using this tablet as it could further lower their blood pressure.
Decompensated Heart Failure: This tablet is contraindicated in patients with uncontrolled, severe heart failure.
Severe Hepatic Impairment: Individuals with severe liver disease should not use this tablet as it could worsen their condition.

Daily Dose

The daily dose of Bisonext AM 5 Tablet should be taken as instructed by your doctor. The dosage could vary based on individual factors such as how severe your condition is and how you respond to the medication. You must follow the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

Overdosing on Bisonext AM 5 Tablet can lead to excessive blood vessel dilation and a too-low heart rate. If you suspect an overdose, it's important to seek medical advice.

Missed Dose

If you forget to take Bisonext AM 5 Tablet as scheduled, take it as soon as you remember. However, if the time is close to your next dose, skip the missed one and continue with your regular schedule. Do not increase your dosage without consulting your doctor.

Store your Bisonext AM 5 Tablet in a cool, dry place at a temperature below 30°C.
Keep the medicine away from direct light and moisture.
Always ensure the medication is kept out of reach of children.
Make sure you use the medicine before its expiry date.

Incorporate low-salt foods in your diet: Reducing your sodium intake can help manage high blood pressure, which Bisonext AM 5 Tablet works to control.
Regular physical activity: Engage in moderate exercise such as walking or cycling for at least 30 minutes a day to help lower blood pressure. Always consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Calcium Channel Blocker, Beta-1 Blocker
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Cardiovascular Risk Reduction

What is Bisonext AM 5 Tablet used for?

Bisonext AM 5 Tablet is used to manage hypertension or high blood pressure. It helps lower the risk of heart attacks and strokes.

How does Bisonext AM 5 Tablet work?

It contains two ingredients, amlodipine and bisoprolol, which work together to relax and widen blood vessels and reduce heart rate, lowering blood pressure.

Can I stop taking Bisonext AM 5 Tablet suddenly?

No, you should not stop taking this medicine suddenly as it may worsen your condition. Always consult your doctor before making any changes.

Can I take Bisonext AM 5 Tablet during pregnancy?

This medicine may harm the foetus. If you're pregnant or planning to be, consult your doctor about the potential risks and benefits.

What are some side effects of Bisonext AM 5 Tablet?

Common side effects include headache, dizziness, fatigue, oedema (swelling), slow heartbeat, nausea, diarrhoea, flushing, stomach pain and insomnia.

Can I take Bisonext AM 5 Tablet with other medicines?

Some medicines may interact with Bisonext AM 5 Tablet. Before starting any new medicine, inform your doctor about all medications you currently take.

How should I store Bisonext AM 5 Tablet?

Store it in a cool, dry place below 30°C. Keep it protected from light and moisture and out of reach of children.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 9 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

References

Pfizer. (1987). NORVASC [Prescribing Information]. In NORVASC (pp. 1–7). https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019787s047lbl.pdf
DailyMed - AMLODIPINE- amlodipine besylate tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b52e2905-f906-4c46-bb24-2c7754c5d75b
Unknown. (n.d.). ZEBETA (BISOPROLOL FUMARATE) TABLETS - bisoprolol fumarate tablet (p. page 1 of 8). https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/019982s014lbl.pdf
Bisoprolol: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00612
Gillessen, A., Randerath, O., Luis, Mockel, Noetel, A., & Seiler, D. (2019). A single pill combining bisoprolol and amlodipine: An open label, multi-dose, single-sequence study to investigate potential pharmacokinetic drug-drug interaction between the two compounds in healthy adult volunteers. https://www.semanticscholar.org/paper/A-single-pill-combining-bisoprolol-and-amlodipine%3A-Gillessen-Randerath/d3db09361f3418ab5d31c75289e5f351e37e3b06

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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