Carmazole 10 Mg Tablet 60

Carmazole 10mg Tablet 60

Synmedic Laboratories

Bottle of 60 Units

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Composition

Carbimazole (10 Mg)

Strength:

5 MG 10 MG

Carmazole 10mg Tablet is primarily used to manage hyperthyroidism, a condition resulting from an overactive thyroid gland. It is part of the thionamide class of medications, known for their anti-thyroid properties.

An important secondary use of this medicine is to help manage hyperthyroid symptoms such as rapid weight loss, a fast heartbeat, mood swings, trembling, and intolerance to heat. Often, Carmazole 10mg Tablet is prescribed in combination with a beta-blocker medication to alleviate these symptoms while the anti-thyroid effects are taking place.

Before starting this medicine, it's crucial to consult your doctor, who will guide you on the correct dosage and frequency. Let your doctor know about any pre-existing conditions or ongoing medications. If you notice any side effects, inform your doctor without delay. It's recommended that you continue taking the medicine for the entire duration prescribed by your doctor for optimal results.

Carmazole 10mg Tablet is primarily used for:

Managing an overactive thyroid gland (hyperthyroidism).
Alleviating hyperthyroid symptoms such as weight loss.
Controlling rapid heartbeat is associated with hyperthyroidism.
Reducing irritability caused by excessive thyroid hormones.
Easing tremors linked to overproduction of thyroid hormones.
Helping to cope with heat intolerance due to hyperthyroidism.

Directions for Use of Carmazole 10mg Tablet 60

Here's how you should take Carmazole 10mg Tablet :

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Always take Carmazole 10mg Tablet at evenly spaced intervals throughout the day.

Carmazole 10mg Tablet is taken orally.

Side Effects of Carmazole 10mg Tablet 60

Carmazole 10mg Tablet may have the following common side effects:

Nausea
Vomiting
Headache
Fever
Joint pain
Changes in taste: You might notice a difference in how your food tastes.
Stomach upset: This can include discomfort, bloating or feeling full too quickly.
Itchy rash: This refers to an uncomfortable, irritating skin condition that makes you want to scratch.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Carmazole 10mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Consider taking Carmazole 10mg Tablet with or after meals to lessen this effect.
Stomach upset: If stomach discomfort is causing trouble, try taking this medicine with food.

Carmazole 10mg Tablet contains carbimazole (10 mg), which has the following actions on your body:

Conversion to Methimazole: After you take Carmazole 10mg Tablet, your body rapidly transforms the carbimazole into its active form, methimazole.
Inhibition of Thyroid Peroxidase: Methimazole works by blocking an enzyme in your body called thyroid peroxidase. This enzyme is crucial for the creation of thyroid hormones.
Reduction in Thyroid Hormones: By blocking thyroid peroxidase, methimazole effectively reduces the levels of the thyroid hormones triiodothyronine (T3) and thyroxine (T4) in your body.
Alleviation of Hyperthyroid Symptoms: With the reduction of thyroid hormones, symptoms of hyperthyroidism such as weight loss, rapid heartbeat, and heat intolerance are managed.

Pregnancy

Caution is advised while taking Carmazole 10mg Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Carmazole 10mg Tablet if you are breastfeeding. Make sure to discuss this with your doctor before starting this medicine.

Alcohol

Consuming alcohol may alter the effect of Carmazole 10mg Tablet, hence, it is advisable to limit alcohol consumption during this medication.

Liver

If you have liver problems, caution is advised while taking Carmazole 10mg Tablet. This medicine may affect liver function. Discuss them with your doctor before starting this medication.

Kidney

If you have kidney issues, caution is advised before using Carmazole 10mg Tablet. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

There are no known effects of Carmazole 10mg Tablet on the ability to drive or operate machinery. However, talk to your doctor if you feel unwell after taking this medicine.

Allergy

If you have any known allergies to carbimazole or any other ingredients in Carmazole 10mg Tablet, do not take this medicine without consulting your doctor.

Children

Carmazole 10mg Tablet is not recommended for children under 18 years of age without a doctor's advice.

Older Patients

Older patients should take Carmazole 10mg Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised for patients over 70 years of age. Your doctor will guide you based on your health status.

Interactions of Carmazole 10mg Tablet 60

Drug-Drug Interactions

Carmazole 10mg Tablet interacts with the following medicines:

Beta Blockers: Medicines like propranolol and atenolol may have their effects enhanced when taken with Carmazole 10mg Tablet, which can slow down your heartbeat more than expected.
Blood Thinners: Anticoagulants like warfarin and heparin might increase their blood thinning effect, potentially leading to excessive bleeding.
Antibiotics: Erythromycin and other similar antibiotics can interact with Carmazole 10mg Tablet, possibly leading to increased levels of thyroid hormones.

Drug-Food Interactions

Certain foods can affect how Carmazole 10mg Tablet works. Here are some examples:

High-Fibre Foods: Foods rich in fibre like whole grains and certain vegetables may decrease the absorption of Carmazole 10mg Tablet, reducing its effectiveness.

Drug-Disease Interactions

Carmazole 10mg Tablet interacts with the following diseases:

Liver Disease: If you have liver disease, Carmazole 10mg Tablet can worsen your condition, as it is metabolised by the liver.
Blood Disorders: People with blood disorders should be cautious as Carmazole 10mg Tablet can cause a severe drop in white blood cells, known as agranulocytosis.
Thyroid Problems: If you have an enlarged thyroid gland, there is a risk that your symptoms could get worse while taking Carmazole 10mg Tablet.

Daily Dose

To manage your condition effectively, take Carmazole 10mg Tablet as prescribed by your doctor. The dosage may vary based on the severity of your condition and how you respond to the medicine. Always follow your doctor's guidance and never adjust your dosage on your own.

Over Dose

If you accidentally take more Carmazole 10mg Tablet than recommended, you may experience symptoms like nausea, vomiting, and headaches. It's important not to panic but let your doctor know about it. Don't take any steps without consulting your doctor.

Missed Dose

If you forget to take Carmazole 10mg Tablet at the scheduled time, take it as soon as you remember. But if it's nearly time for the next dose, skip the missed one and continue with your regular schedule. Never double up the dose to make up for a missed one.

Keep Carmazole 10mg Tablet in a cool, dry place where the temperature stays below 25°C.
Avoid exposure to direct sunlight and moisture.
Ensure the medicine is out of sight and reach of children.
Use the medicine before its expiry date marked on the packaging.

Since hyperthyroidism can cause rapid weight loss, ensure you consume a balanced diet rich in proteins, complex carbohydrates, and healthy fats to maintain your weight.
Engage in calming activities such as yoga or meditation to manage symptoms like irritability and anxiety associated with an overactive thyroid gland.

Fact Box

Drug Category	Thionamide Anti-Thyroid
Therapeutic Category	Anti-Hyperthyroidism
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hyperthyroidism

How long does it take for Carmazole 10mg Tablet to work?

Typically, hyperthyroidism symptoms start improving within 3-4 weeks after starting this medicine. However, full control of thyroid hormone levels can take several months.

Can I take Carmazole 10mg Tablet for a long time?

Usually, this medicine is taken for 12-18 months. However, your doctor may recommend longer usage in some cases.

Do I need to follow a special diet while taking Carmazole 10mg Tablet?

Your doctor might suggest limiting foods rich in iodine like seafood and iodised salt to aid in managing your thyroid condition.

Can I become pregnant while taking Carmazole 10mg Tablet?

Carmazole 10mg Tablet can harm an unborn baby. Use reliable contraception during treatment and inform your doctor immediately if you become pregnant.

What should I do if I experience side effects from Carmazole 10mg Tablet?

If you experience bothersome side effects or signs of a serious reaction, contact your doctor immediately. Don't stop the medicine without consulting your doctor.

Is regular monitoring necessary when taking Carmazole 10mg Tablet?

Yes, regular blood tests are essential when taking this medicine to check white blood cell counts, liver function, and thyroid hormone levels.

How should I store my Carmazole 10mg Tablet?

Store these tablets at room temperature in a cool, dry place away from direct sunlight and moisture. Keep it out of children's and pets' reach.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Sai Sadan, 202, 187-188, Sant Nagar, East of Kailash, New Delhi, Delhi 110065

Country of origin: INDIA

References

National Health Service. (n.d.). Carbimazole. Retrieved 1 April 2024, from https://www.nhs.uk/medicines/carbimazole/
Gupta, S. K., Mithal, A., & Godbole, M. M. (1992). Single daily dose of carbimazole in the treatment of hyperthyroidism. The National medical journal of India, 5(5), 214–216. https://pubmed.ncbi.nlm.nih.gov/1302580/
Page, S. R., Sheard, C. E., Herbert, M., Hopton, M., & Jeffcoate, W. J. (1996). A comparison of 20 or 40 mg per day of carbimazole in the initial treatment of hyperthyroidism. Clinical endocrinology, 45(5), 511–516. https://doi.org/10.1046/j.1365-2265.1996.00800.x
Khan, Z., Afifi, W., Muhammad, S. A., & Warrier, V. (2022). Carbimazole-Induced Agranulocytosis in a Previously Stable Patient: A Case Report and Literature Review. Cureus, 14(4), e24115. https://doi.org/10.7759/cureus.24115
Carbimazole: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00389

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